Blood lipid level related single nucleotide polymorphism rs4883263 detecting system and related application
A polymorphism, horizontal technology, applied in the direction of microbial determination/inspection, biochemical equipment and methods, etc., can solve the problem of lack of Asian population research data and so on
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[0024] The invention is divided into two stages (preliminary screening stage and verification stage) to respectively detect and analyze the genetic variation related to TC, LDL-C, HDL-C and TG.
[0025] The research population included 47,532 subjects in the first phase and 13,408 subjects in the validation phase. All studies included a total of 61,669 East Asian populations. Each study was approved by the ethics committee of its research institution and the local investigating agency. All participants signed informed consent in writing.
[0026]In the first stage, a meta-analysis of the exome association study was conducted on 47,532 survey subjects in the East Asian population. 47,532 subjects, from China Eye Study (CHES), China Health and Nutrition Survey (CHNS), Fangchenggang Male Health Examination Survey (FAMHES), Guizhou Bijie Type 2 Diabetes Study (GBTDS), Hong Kong University Special Research Program (HKU-TRS) ), Hubei Coronary Heart Disease Study (HuCAD) and Chines...
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