Sample liquid drop granular forming device

Abstract

The invention discloses a sample liquid drop granular forming device. The sample liquid drop granular forming device is used for solving problems in the prior art that it is inconvenient for forming of in vitro molecular diagnosis sample sampling liquid drop, the stability and the uniformity of the formed liquid drops are poor, pollution by the external environment is easily caused, and detectionaccuracy is low. The sample liquid drop granular forming device comprises a machine frame, and a fluid driver; the lower end of the machine frame is connected with a bottom plate; a sample support, apipette head support, and a carrying packaging chip are arranged on the bottom plate; a slide carriage is arranged on the machine frame, and is designed to be capable of moving transversely; the lowerend of the slide carriage is provided with a lifting pedestal capable of lifting; the lifting pedestal is connected with a liquid drop forming machine head part capable of vibrating; a pipette head pedestal matching pipette heads is arranged on the liquid drop forming machine head part; the carrying packaging chip comprises a chip main body; the chip main body is provided with an oil collecting tank, an inclined slide, a liquid drop storing tank, an oil discharge runner, a liquid level control oil tank, and an oil storing tank; the oil collecting tank is connected with an elastic sealing cover; and the chip main body is provided with gas vent communicated with the oil storing tank.

Description

technical field [0001] The invention relates to the fields of in vitro molecular diagnosis and biological gene research, more specifically, it relates to a sample droplet particle forming device. Background technique [0002] At present, fluorescence quantitative PCR (Fluorescence Quantitative Polymerase Chain Reaction, qPCR) has developed into a key routine technology in the field of in vitro molecular diagnosis, which has greatly promoted the development of life science in the field of health care. However, fluorescent quantitative PCR quantification is only relative quantification, and its accuracy and reproducibility still cannot meet the requirements of current in vitro molecular diagnostic systems and biological genetics research. In addition, due to the inhibitory effect of PCR amplification products on enzyme-catalyzed reactions, gene variation detection methods based on current qPCR technology are often powerless for low-abundance gene variations in somatic cells. ...

AI Technical Summary

Problems solved by technology

[0004] The invention overcomes the inconvenient formation of in vitro molecular diagnostic sample sampling droplet particles, the formed droplet has poor stability and uniformity, and is easily polluted by the outside world, thereby affecting the accuracy of detection, and provides a sample droplet particle Forming device, it is convenient to form droplet particles, the formed droplet has good stability and uniformity, and is not easy to be polluted by the outside world, ensuring the accuracy of detection and avoiding the occurrence of false positives

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