Inhaler device
A technology of inhaler and container, applied in the field of inhaler equipment
Inactive Publication Date: 2018-03-27
CIPLA EURO NV
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- Abstract
- Description
- Claims
- Application Information
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Problems solved by technology
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Method used
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[0117]
[0118] Manufacturing process:
[0119] 1) Disperse recombinant human insulin in water
[0120] 2) Add citric acid to dissolve insulin, then add mannitol / trehalose / raffinose / sodium alginate and glycine
[0121] 3) Add sodium citrate to the solution obtained in step (2), and adjust the pH with sodium hydroxide, and spray dry to provide a powdered medicament suitable for delivery by the inhaler of the present invention.
[0122] It will be understood that the present invention has been described above by way of example only and that modifications may be made in detail without departing from the scope of the claims.
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An inhaler (1) for delivering a powdered medicament (2) to a user from a container (4), comprising a flow channel (6), an opening means (8) and a housing (10). The flow channel comprises a conduit (16) extending from an inlet (18) to an outlet (20) and including a medicament introduction region (22). The housing includes a loading member (24) coupled thereto which includes a holder (26) for receiving and retaining the container. The loading member can be manually moved by a user between a loading position, in which a container can be manually loaded into the holder, and an inhalation positionin which the medicament in the container can be introduced into the flow channel. The movement of the loading member from the loading position to the inhalation position causes the opening means to break a seal on the container, thereby exposing the medicament for introduction into the flow channel.
Description
technical field [0001] The present invention relates to an inhaler device for delivering powdered medicament from a sealed container to a user. In particular the invention relates to a reloadable single unit or single dose inhaler device which receives a sealed container containing a powdered medicament to be delivered to a patient. Background technique [0002] Various types of dry powder inhaler devices are known, including single-dose, multiple unit-dose and multi-dose devices. Single-dose inhalers are typically operable such that a capsule (such as a gelatin capsule) containing the medicament can be placed in the reservoir region of the inhaler. The capsule must be opened or pierced to allow part of the inhaled air flow to enter the capsule for medicament entrainment or to expel powder from the capsule during inhalation. Typically, this is accomplished by opening or penetrating the capsule with a pin or cutting blade to allow the powder to exit the capsule. After inha...
Claims
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IPC IPC(8): A61M15/00A61M11/06
CPCA61M11/06A61M15/0028A61M2202/064A61M2206/16A61M15/0021A61M15/0036A61M15/004A61M15/0035
Inventor 弗兰克·彼得斯吉纳·马尔霍特拉
Owner CIPLA EURO NV



