Children Kaihoujian spray as well as preparation and quality standard inspection method thereof

Abstract

The invention discloses a children Kaihoujian spray as well as a preparation and quality standard inspection method thereof. The children Kaihoujian spray is prepared from four Chinese herbs such as ardisia crispa, radix sophorae subprostratae, periostracum cicada and menthol; in an identification process, the thin-layer identification of radix ardisiae crenataeis is corrected, in an original standard, the identification is performed by referring to bergenin, a test sample preparation method is complex, the original method is modified, a radix ardisiae crenataeis reference herb is added, so that the test sample preparation method is simplified, and the method is high in specificity and good in repetition and is listed in the standard text; the language description for identifying a mentholthin layer is standardized, and a reagent benzene used for the developing agent is replaced as methylbenzene; and the thin-layer identification of the radix ardisiae crenataeis is added, sophocarpidine is adopted as a reference, and by virtue of examination, the method is stable and good in repetition, thereby being listed in the standard text. In addition, the research is made for the thin-layeridentification of periostracum cicada.

Description

technical field [0001] The invention relates to the technical field of medicine preparation and quality control thereof, in particular to a children's Kaihoujian spray and its preparation and quality standard inspection method. Background technique [0002] The quality standard of Kaihoujian spray (child type) is now recorded in the National Drug Standard WS-10132(ZD-0132)-2002-2012Z of the State Food and Drug Administration, and the drug approval number is Z20025142; Composed of four flavors of traditional Chinese medicine, the original standard uses petracenin as a control for identification, the preparation method of the test sample is complicated, and lacks the identification method of cinnabar and the reference medicinal material, and lacks the content determination method of the active ingredient petracenin in cinnabar root; the original quality The developer used for menthol in the standard is the reagent benzene, and at the same time, it lacks the TLC identification ...

AI Technical Summary

Problems solved by technology

[0002] The quality standard of Kaihoujian spray (child type) is now recorded in the National Drug Standard WS-10132(ZD-0132)-2002-2012Z of the State Food and Drug Administration, and the drug approval number is Z20025142; Composed of four flavors of traditional Chinese medicine, the original standard uses petracenin as a control for identification, the preparation method of the test sample is complicated, and lacks the identification method of cinnabar and the reference medicinal material, and lacks the content determination method of the active ingredient petracenin in cinnabar root; the original quality The developer used for menthol in the standard is the reagent benzene, and at the same time, it lacks the TLC identification of mountain bean root

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