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Method for extracting sialic acid from bird's nests

A technology of bird's nest acid and bird's nest, applied in chemical instruments and methods, preparation of sugar derivatives, sugar derivatives, etc., can solve the problems of loss of activity, reduced activity, difficult to degrade, etc., and achieve simple equipment, simple process, and easy operation and control Effect

Inactive Publication Date: 2018-05-08
广西佛斯肽生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] According to reports, modern pharmacological research shows that bird's nest not only has extremely rich nutrients, but also contains a variety of biologically active substances, such as bird's nest acid, bird's nest cell division hormone, epidermal growth factor, etc. These biologically active substances have important biological effects on the human body. Regulatory effect, but according to the traditional eating method, these biologically active substances in bird’s nest are tightly combined with glycoprotein and mucin in bird’s nest, and it is difficult to degrade and be absorbed in the body, and their physiological effects cannot be fully exerted
In addition, when these biologically active substances are subjected to factors such as acid, alkali, temperature, and enzymes in the supercritical range, they will suffer certain damage and reduce their activity, or even lose their activity.

Method used

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  • Method for extracting sialic acid from bird's nests
  • Method for extracting sialic acid from bird's nests

Examples

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Embodiment 1

[0042] A method for extracting bird's nest acid from bird's nest, comprising the steps of:

[0043] (1) Dry the bird’s nest in an electric oven for 2 hours to make the bird’s nest dehydrated and brittle; the temperature of the electric oven is 50° C.;

[0044] (2) pulverize the dried bird's nest with a pulverizer to obtain bird's nest powder; the fineness of the bird's nest powder is 80 orders;

[0045] (3) Soak the bird's nest powder with deionized water for 3 hours, so that the fully absorbed water will expand to 5 times, and become translucent colloidal particles; the temperature of the deionized water is 50 ° C;

[0046](4) Use a colloid mill to grind the soaked bird’s nest powder together with the soaking water, grind it circularly for 8 minutes, and grind it into a 120-mesh bird’s nest slurry, add deionized water to make the solid-liquid ratio reach 1:30, and then use dilute NaOH solution to adjust the pH value of the slurry to 10.6, mix by colloid mill;

[0047] (5) P...

Embodiment 2

[0055] A method for extracting bird's nest acid from bird's nest, comprising the steps of:

[0056] (1) Dry the bird’s nest in an electric oven for 3 hours to make the bird’s nest dehydrated and brittle; the temperature of the electric oven is 50° C.;

[0057] (2) pulverize the dried bird's nest with a pulverizer to obtain bird's nest powder; the fineness of the bird's nest powder is 80 orders;

[0058] (3) Soak the bird's nest powder with deionized water for 4 hours, so that the water can be fully absorbed and expanded to 6 times, and become translucent colloidal particles; the temperature of the deionized water is 60 ° C;

[0059] (4) Use a colloid mill to grind the soaked bird’s nest powder together with the soaking water, grind it circularly for 10 minutes, and grind it into a 120-mesh bird’s nest slurry, add deionized water to make the solid-liquid ratio reach 1:30, and then use dilute NaOH solution to adjust the pH value of the slurry to 10.6, mix by colloid mill;

[0...

Embodiment 3

[0068] A method for extracting bird's nest acid from bird's nest, comprising the steps of:

[0069] (1) Dry the bird’s nest in an electric oven for 2.5 hours to make the bird’s nest dehydrated and brittle; the temperature of the electric oven is 50° C.;

[0070] (2) pulverize the dried bird's nest with a pulverizer to obtain bird's nest powder; the fineness of the bird's nest powder is 80 orders;

[0071] (3) Soak the bird's nest powder with deionized water for 3.5 hours, so as to fully absorb the water and expand to 5 times, and become translucent colloidal particles; the temperature of the deionized water is 55 ° C;

[0072] (4) Use a colloid mill to grind the soaked bird’s nest powder together with the soaking water, grind it circularly for 9 minutes, and grind it into a 120-mesh bird’s nest slurry, add deionized water to make the solid-liquid ratio reach 1:30, and then use dilute NaOH solution to adjust the pH value of the slurry to 10.6, mix by colloid mill;

[0073] (5...

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Abstract

The invention belongs to the technical field of deep processing of bird's nest products and particularly relates to a method for extracting sialic acid from bird's nests. The method disclosed by the invention comprises the steps of firstly, crushing the bird's nests until the particle size is 80 meshes, soaking the bird's nest particles in hot deionized water with the temperature of 50 DEG C to 60DEG C for 3 to 4 hours to subject the bird's nest particles to thorough imbibition, carrying out circular grinding with a colloidal mill to obtain bird's nest pulp with the particle size of 120 meshes, subjecting bird's nest cells to wall breaking by a microwave function so as to release the sialic acid from glycoprotein and mucus protein, removing macromolecular substances by using microfiltration and 2-level ultrafiltration of a membrane technology according to the characteristic that the molecular weight of the sialic acid is small, trapping substances of 150Da to 500Da by using a nano-filtration membrane, and subjecting trapped fluid of 150Da to 500Da to concentrating, freezing and microwave vacuum depressurization drying, thereby obtaining the sialic acid. According to the method disclosed by the invention, the content of the obtained sialic acid is 80% or more, and the recovery rate of the sialic acid reaches 90%.

Description

technical field [0001] The invention belongs to the technical field of bird's nest product deep processing, and in particular relates to a method for extracting bird's nest acid from bird's nest. Background technique [0002] According to traditional Chinese medicine, bird's nest is sweet in taste, flat in nature and non-toxic. Go into lung, stomach, kidney three warps. Function: Nourishing yin and moistening dryness, replenishing qi and invigorating the middle, reducing phlegm and relieving cough. Indications: chronic illness and weakness, tuberculosis cough, phlegm and dyspnea, hemoptysis, hematemesis, chronic dysentery, chronic malaria, choking and nausea, weak spermatorrhea, frequent urination, etc. Medication contraindications: Take it with caution in those with warm phlegm stagnation and external evils. Therefore, for a long time, bird's nest has been used as a high-end food with the same reputation as bear's paw and shark's fin, and it has been taken as a strong to...

Claims

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Application Information

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IPC IPC(8): C07H13/06C07H1/08
CPCC07H1/08C07H13/06
Inventor 储朝霞
Owner 广西佛斯肽生物科技有限公司
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