A kind of gastric ulcer toothpaste and preparation method thereof

A technology for relieving stomach ulcers and toothpaste, which is applied in dentistry, pharmaceutical formulations, cosmetic preparations, etc. It can solve the problems of reducing the self-healing ability of oral tissues, the lack of targeted antibacterial active ingredients, and the low content of active ingredients in toothpaste. Achieve the effects of improving self-healing ability and oral repair ability, good antibacterial, anti-inflammatory and pain-relieving effects, and good therapeutic effect

Active Publication Date: 2021-08-06
惠州市九惠制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Among the traditional Chinese medicine toothpastes currently on the market, some toothpastes contain relatively single types of traditional Chinese medicines and single functions, and have not exerted the synergistic effect produced by the compatibility of traditional Chinese medicinal materials; some of them contain too many traditional Chinese medicine prescriptions, resulting in complex composition , so that the content of active ingredients that are already limited in toothpaste is lower
In addition, the antibacterial active ingredients used in these toothpastes are not highly targeted and have broad-spectrum antibacterial properties, which can also inhibit the non-pathogenic resident bacteria in the oral cavity and reduce the self-healing ability of oral tissues to damage

Method used

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  • A kind of gastric ulcer toothpaste and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A stomach ulcer toothpaste, comprising the following components in parts by weight: 0.5 parts of stomach ulcer, 0.24 parts of pilose antler extract, 0.24 part of Scutellaria baicalensis extract, 80 parts of toothpaste base; the stomach ulcer is extracted from licorice Drug;

[0036] Wherein, the toothpaste base comprises the following components in parts by weight:

[0037] 30 parts of friction agent silicon dioxide, 15 parts of excipient sorbitol, 30 parts of humectant is a mixture of propylene glycol and polyethylene glycol, 1.4 parts of thickener silicon dioxide, 0.8 parts of essence bamboo leaf essence, foaming agent 1.6 parts of sodium lauryl sulfate, 1.2 parts of sweetener aspartame, and 0.2 parts of breath freshener bamboo leaf extract.

[0038] The toothpaste of the present embodiment is made by following preparation method, and concrete steps are:

[0039] (1) Decoct velvet antler and scutellaria baicalensis with purified water twice, each time for 1.5 hours,...

Embodiment 2

[0043] A stomach ulcer toothpaste, comprising the following components in parts by weight: 0.4 parts of stomach ulcer, 0.20 parts of pilose antler extract, 0.20 part of Scutellaria baicalensis extract, 75 parts of toothpaste base; the stomach ulcer is extracted from licorice Drug;

[0044] Wherein, the toothpaste base comprises the following components in parts by weight:

[0045] 31 parts of calcium hydrogen phosphate dihydrate abrasive, 15 parts of excipient sorbitol, 31 parts of humectant glycerin, 1.4 parts of thickener silicon dioxide, 0.8 parts of dried ginger essence, 1.6 parts of foaming agent sodium lauryl sulfate , sweetener sodium saccharin 1.2 parts, breath freshener lemon extract 0.05 parts.

[0046] The toothpaste of the present embodiment is made by following preparation method, and concrete steps are:

[0047] (1) Decoct velvet antler and scutellaria baicalensis with purified water twice, each time for 1.5 hours, combine the decoction liquid, filter, concentr...

Embodiment 3

[0051] A stomach ulcer toothpaste, comprising the following components in parts by weight: 0.6 parts of stomach ulcer, 0.33 parts of pilose antler extract, 0.30 part of scutellaria baicalensis extract, 86 parts of toothpaste base; the stomach ulcer is extracted from licorice Drug;

[0052] Wherein, the toothpaste base comprises the following components in parts by weight:

[0053] 32 parts of abrasive silicon dioxide, 17 parts of excipient sorbitol, 31 parts of humectant sorbitol, 1.6 parts of thickener silicon dioxide, 1.1 parts of bamboo leaf essence, 1.8 parts of foaming agent sodium lauryl sulfate, Sweetener aspartame 1.5 parts, breath freshener lemon extract 0.3 parts.

[0054] The toothpaste of the present embodiment is made by following preparation method, and concrete steps are:

[0055] (1) Decoct velvet antler and scutellaria baicalensis with purified water twice, each time for 1.5 hours, combine the decoction liquid, filter, concentrate and dry into a paste, and o...

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Abstract

The invention provides a toothpaste for stomach ulcers, which comprises the following components in parts by weight: 0.3-0.6 parts for stomach ulcers, 0.18-0.33 parts of pilose antler extract, 0.18-0.33 parts of Scutellaria baicalensis extract, and 73-86 parts of toothpaste base Parts; described stomach ulcer is the medicine extracted from Radix Glycyrrhizae. The Anweiyang toothpaste has good antibacterial, anti-inflammatory and analgesic effects, and has a good ability to repair oral cavity due to its highly targeted inhibition of pathogenic bacteria; It has good therapeutic effect, its formula is scientific and reasonable, and the three kinds of traditional Chinese medicines synergistically enhance the curative effect, and the cost of raw materials is low, and the cost performance is high. The present invention also provides the preparation method of the stomach ulcer toothpaste, which can fully extract and protect the effective antibacterial and bactericidal components in stomach ulcer, pilose antler and scutellaria baicalensis, and ensure that the active ingredients in the toothpaste can play a role in preventing pathogenic bacteria. Inhibition and killing effect, so as to effectively prevent and treat oral inflammation.

Description

technical field [0001] The invention relates to the technical field of oral care and health care, in particular to a stomach-relieving toothpaste and a preparation method thereof. Background technique [0002] Oral inflammation mainly includes ulcerative, herpetic and fungal stomatitis, and oral lichen planus. There is a great possibility that various oral inflammations coexist. Among them, the incidence rate of recurrent oral ulcer is relatively high, which has the characteristics of periodicity, recurrence and self-limitation. Patients with severe oral ulcers may also be accompanied by complications such as swollen and painful gums and bleeding gums. As a common oral disease, oral ulcers are caused by viruses or bacteria, generally caused by Streptococcus, Staphylococcus aureus, and Escherichia coli, and are also related to the decline in autoimmunity. It is a disease characterized by periodic recurrence. Oral mucosal ulcer damage can occur in any part of the oral mucos...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/9794A61Q11/00A61Q17/00A61P1/02A61P31/02A61P31/04
CPCA61K8/97A61K2800/5922A61Q11/00A61Q17/005
Inventor 黄辉球黄志刚叶红斌文振璀
Owner 惠州市九惠制药股份有限公司
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