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A sort of 12 c 6+ Method for preparing oregano essential oil microcapsules by ion beam irradiation

An ion beam, microcapsule technology, applied in the directions of microcapsules, capsule delivery, plant/algae/fungus/moss components, etc., can solve the limitation of oregano essential oil microcapsule application, it is difficult to meet the slow release and stability, easy to use. Diffusion and other problems, to achieve the effect of easy industrialization, prevention of oxidation and loss, and wide reaction temperature

Active Publication Date: 2020-09-08
河南华牧生物科技有限公司
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Problems solved by technology

Although the oregano essential oil microcapsules prepared by conventional techniques have good moisture retention, rheology and lubricity, it is found in clinical application that this dosage form is easy to diffuse in animal tissues and is easily degraded by oxidative substances or enzymes in the animal body, making it difficult to The sustained release and stability that meet the requirements of some special situations limit the clinical application of oregano essential oil microcapsules

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  • A sort of <sup>12</sup> c <sup>6+</sup> Method for preparing oregano essential oil microcapsules by ion beam irradiation
  • A sort of <sup>12</sup> c <sup>6+</sup> Method for preparing oregano essential oil microcapsules by ion beam irradiation
  • A sort of <sup>12</sup> c <sup>6+</sup> Method for preparing oregano essential oil microcapsules by ion beam irradiation

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Embodiment Construction

[0038] In order to highlight the purpose, technical solutions and advantages of the present invention, the present invention will be further described in conjunction with the following examples, but the present invention is not limited within the scope of the examples.

[0039] One, the preparation of oregano essential oil microcapsules

[0040] 1 material

[0041] Analytical pure oregano essential oil Huamei Natural Vegetable Oil Refining Plant; chitosan analytical pure bioengineering; Eucommia gum: prepared by the Pharmacy Department of Lanzhou Institute of Animal Husbandry and Veterinary Medicine, Chinese Academy of Agricultural Sciences. WJE-880 is analytically pure from Shanghai Wanjin Auxiliary Co., Ltd., and other chemical reagents are analytically pure from Tianjin Reagent Factory.

[0042] 2 Irradiation method

[0043] The irradiation experiment was carried out at the biological irradiation terminal of Lanzhou Heavy Ion Research Facility (HIRFL). The initial energy...

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Abstract

The invention discloses a method for preparing oregano essential oil microcapsules by irradiation with a <12>C<6+> ion beam. The method comprises adding oregano essential oil into a mixed solution ofchitosan and eucommia gum, simultaneously, adding an emulsifier into the mixture, carrying out inclusion, and carrying out irradiation with a <12>C<6+> ion beam to obtain the oregano essential oil microcapsules. The method is free of an initiator, does not introduce impurity groups, produces pure products and is used for any monomer polymerization or grafting modification of chitosan and eucommiagum and thus in the essential oil microencapsulation based on the irradiation with a <12>C<6+> ion beam, the method is better than many pure chemical polymerization methods. The method has a wide reaction temperature range, has no pressure requirements and is not limited by a system state. The reaction process can adjust and control processes through control of conventional chemical technical parameters and an irradiation dose rate, is easy to promote in the industry, saves energy, reduces emission and protects the environment. The microcapsule technology is used in essential oil production and prevention and treatment on chicken coccidiosis and greatly improves the quality of essential oil products.

Description

technical field [0001] The present invention relates to a 12 C 6+ Method for preparing oregano essential oil microcapsules by ion beam irradiation. Background technique [0002] Origanum vuLgare L. is a herbaceous plant belonging to the genus Origanum of the Labiatae family. It belongs to traditional Chinese herbal medicine. It is mainly distributed in Northwest China, North China and south of the Yangtze River in my country. Extraction of oregano essential oil can be realized by including steam distillation extraction method, supercritical fluid extraction method and the like. Oregano essential oil is a light yellow clear oily liquid, containing more than 30 kinds of volatile components, so it is very volatile and not easy to preserve. The main biologically active components are carvacrol and thymol. It not only has antibacterial effect, but also has antimalarial protozoa and coccidiosis activity, and is effective against poison, tenderness, metamorphosis, stack type and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/52A61K36/53A61K47/36A61P31/02
CPCA61K9/5036A61K36/53
Inventor 梁剑平刘宇陶蕾郝宝成周玉岩王学红郭文柱赵凤舞杨珍贾忠张新刚王震陈虹樊华
Owner 河南华牧生物科技有限公司
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