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Vulva washing lotion containing polylysine and preparation method thereof

A technology of polylysine and vulva, which is applied in the field of daily chemical care products to achieve the effect of maintaining lubrication and resistance, maintaining the cleanliness of the genitals, and facilitating mass production

Inactive Publication Date: 2018-06-22
NANYANG NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no vaginal drug preparation in the commercially available ε-polylysine preparation. Therefore, it is of great significance to prepare a vaginal lotion with no side effects, quick effect and convenient preparation.

Method used

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  • Vulva washing lotion containing polylysine and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Weighing: ε-polylysine 0.1g, propylene glycol 2g, sodium dodecylbenzenesulfonate 0.1g, borneol 0.5g, vitamin E 0.05g, pure water 100mL.

[0038] (1) Put sodium dodecylbenzenesulfonate and vitamin E in absolute ethanol, pour the alcohol solution into pure water and stir, remove the ethanol in the solution in a constant temperature water bath at 80°C for 6 minutes, and cool to room temperature to obtain a surfactant aqueous solution.

[0039] (2) Add ε-polylysine to the aqueous surfactant solution in (1), and stir in a constant temperature water bath at 40°C to dissolve the ε-polylysine completely.

[0040] (3) Add propylene glycol and borneol to (2), stir in a constant temperature water bath at 40°C, and stir at 200r / min for 1min.

[0041] (4) adding lactic acid to adjust the pH value of step (3) to 4.5.

[0042] (5) Sterilize the prepared solution (4).

Embodiment 2

[0044] Weighing: ε-polylysine 3g, glycerol 8g, sophorolipid 0.15g, borneol 1g, vitamin E 0.07g, pure water 100mL.

[0045] (1) Dissolve sophorolipids and vitamin E in absolute ethanol, pour the alcohol solution into pure water and stir, remove the ethanol in the solution in a constant temperature water bath at 85°C for 8 minutes, and cool to room temperature to prepare an aqueous surfactant solution.

[0046] (2) Add ε-polylysine to the aqueous surfactant solution in (1), and stir in a constant temperature water bath at 45°C to dissolve ε-polylysine completely.

[0047] (3) Add glycerol and borneol to (2), stir in a constant temperature water bath at 45°C, and stir at 300r / min for 2min.

[0048] (4) adding sodium lactate to adjust the pH value of step (3) to be 5.

[0049] (5) Sterilize the prepared solution (5).

Embodiment 3

[0051] Weighing: ε-polylysine 5g, sodium hyaluronate 15g, lecithin 0.2g, borneol 1.5g, vitamin E 0.09g, pure water 100mL.

[0052] (1) Dissolve lecithin and vitamin E in absolute ethanol, pour the alcohol solution into pure water and stir, remove the ethanol in the solution in a constant temperature water bath at 90°C for 10 minutes, and cool to room temperature to prepare an aqueous surfactant solution.

[0053](2) Add ε-polylysine to the surfactant aqueous solution in (1), and stir in a constant temperature water bath at 50°C to dissolve ε-polylysine completely.

[0054] (3) Add sodium hyaluronate and borneol to (2), stir in a constant temperature water bath at 50°C, and stir at 400r / min for 3min.

[0055] (4) adding lactic acid to adjust the pH value of step (3) to 5.5.

[0056] (5) Sterilize the prepared solution (3).

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Abstract

The invention discloses vulva washing lotion containing polylysine. The vulva washing lotion is prepared from the following raw materials in weight percent: 0.1-5wt% of Epsilon-polylysine, 2-15wt% ofmoisturizing lubricant, 0.1-0.2wt% of surfactant, 0.5-1.5wt% of borneol, 0.05-0.09wt% of vitamin E, and the balance of pure water; and the pH value of the vulva washing lotion is 4.5-5.5. The invention further provides a preparation method of vulva washing lotion containing polylysine. The washing lotion has the advantages of being fast in taking effect, good in antibacterial effect, gentle and harmless for the human body, free from toxic and side effect, and hard to relapse; and the washing lotion is free from antibiotic and has no drug resistance after being used.

Description

technical field [0001] The technical field of daily chemical care products of the present invention, in particular, relates to a vulva lotion containing polylysine and a preparation method thereof. Background technique [0002] The cleanliness of the genitals of men and women is very important. The cuticle of the genitals is relatively thin. In addition to the general sweat glands, there are many special sebaceous glands under the hair of the genitals. These glands also secrete sweat, which is easy to breed and infect bacteria and viruses, causing itching , inflammation and other diseases, through clinical testing, often caused by infection with Candida albicans, chlamydia, mycoplasma, diplococcus or other bacteria; due to some conceptual errors and untimely care, problems in the genitals such as female vulva vaginal itching, Odor, increased secretions, swelling and pain, and male infection can easily cause diseases such as balanitis, and vaginal infection is recurrent, whic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/88A61K8/67A61K8/34A61Q19/10A61Q17/00A61K31/355A61K31/045A61K31/785A61K9/08A61K47/10A61K47/36A61P15/02A61P31/02A61P31/10A61P33/02A61P17/02A61P17/04
CPCA61K8/34A61K8/678A61K8/88A61K9/0034A61K9/08A61K31/045A61K31/355A61K31/785A61K47/10A61K47/36A61Q17/005A61Q19/10A61K2300/00
Inventor 惠丰立刘开放席志文岳金茹
Owner NANYANG NORMAL UNIV
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