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A blood-increasing medicinal composition and preparation method thereof

The technology of a composition and a drug is applied in the field of blood-raising drug composition and its preparation, which can solve the problems of toxicity, high price, hair loss and the like, and achieve the effect of reducing the decline of blood picture, low price and good tumor.

Active Publication Date: 2020-10-09
BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. Hair loss, some chemotherapy drugs may cause hair loss, but hair loss is reversible, and new hair will grow back after stopping chemotherapy
3. Hematological toxicity, such as leukocyte and thrombocytopenia, etc.
For the leukopenia caused by chemotherapy, the commonly used clinical treatment methods are oral leucopenia drugs such as Likejun, leucamine, etc., and G-CSF is used for severe cases; rhEPO is given for anemia, and blood transfusion is used for severe cases; IL-11 or blood transfusion is used for thrombocytopenia. TPO treatment, most of these methods are expensive, or have adverse reactions of different severity

Method used

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  • A blood-increasing medicinal composition and preparation method thereof
  • A blood-increasing medicinal composition and preparation method thereof
  • A blood-increasing medicinal composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A medicinal composition for increasing blood, which is composed of the following raw materials: 30 parts by weight of raw astragalus, 15 parts by weight of fried Atractylodes macrocephala, 30 parts by weight of Caulis Spatholobus, 15 parts by weight of medlar, 10 parts by weight of dodder, 15 parts by weight of Polygonatum, and 3 parts by weight of cinnamon Parts by weight, 3 parts by weight of Asarum, 3 parts by weight of Borneolum;

[0026] The preparation method of the blood-increasing pharmaceutical composition is to take the crude drug, add 5-8 times of water to decoct 1-2 times, each time for 1-1.5 hours, centrifugally filter the medicinal solution, concentrate, dry, and pulverize to obtain an extract powder, add 0.2-1.0% by weight of borneol and mix evenly to obtain.

Embodiment 2

[0028] A medicinal composition for increasing blood, which is composed of the following raw materials: 40 parts by weight of raw astragalus, 25 parts by weight of fried Atractylodes macrocephala, 30 parts by weight of Caulis Spatholobus, 25 parts by weight of medlar, 10 parts of dodder, 20 parts of Polygonatum, and 6 parts of cinnamon , 6 parts of asarum, 2 parts of borneol;

[0029] The preparation method of the blood-increasing pharmaceutical composition is characterized in that: take the raw material drug, add 6 times of water to decoct twice, each time for 1 hour, centrifugally filter the medicinal solution, then heat and concentrate on a water bath, vacuum dry, and pulverize. Sieve to get extract powder, add 0.5% by weight borneol and mix evenly to obtain final product;

[0030] Clean the umbilicus with 75% medical alcohol before application, fill the umbilicus with medicinal powder, fix it with cotton balls and a film, avoid contact with water, apply 1 patch a day, and r...

Embodiment 3

[0032] A medicinal composition for promoting blood, which is composed of the following raw materials: 25 parts by weight of raw astragalus, 15 parts by weight of fried Atractylodes macrocephala, 25 parts by weight of Caulis Spatholobus, 12 parts by weight of medlar, 15 parts of dodder, 20 parts of Polygonatum, and 2 parts of cinnamon , Asarum 2 parts, borneol 1 part;

[0033] The preparation method of the blood-increasing pharmaceutical composition is characterized in that: take the raw material drug, add 6 times of water to decoct twice, each time for 1 hour, centrifugally filter the medicinal solution, then heat and concentrate on a water bath, vacuum dry, and pulverize. Sieve to obtain extract powder, add 0.5% by weight borneol and mix evenly to obtain final product.

[0034] Clean the umbilicus with 75% medical alcohol before application, fill the umbilicus with medicinal powder, fix it with cotton balls and a film, avoid contact with water, apply 1 patch a day, and remove...

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Abstract

The invention discloses a blood nourishing medicine composition which comprises the following raw materials: 20-60 parts by weight of raw astragalus mongholicus, 10-15 parts by weight of roasted bighead atractylodes rhizome, 20-60 parts by weight of caulis spatholobi, 10-50 parts by weight of fructus lycii, 5-20 parts by weight of cuscuta chinensis, 10-50 parts by weight of polygonatum sibiricum,1-8 parts by weight of cassia bark, 1-8 parts by weight of herba asari cum radice herba asari cum radice and 1-8 parts by weight of borneol. The invention further discloses a preparation method of theblood nourishing medicine composition. The blood nourishing medicine composition has a certain haematological protective effect on leukopenia caused by tumor chemotherapy, and particularly has obvious advantages in aspects of increasing a leucocyte count, improving traditional Chinese medicine symptoms and improving life quality in a later treatment stage.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a blood-increasing pharmaceutical composition and a preparation method thereof. Background technique [0002] At present, chemotherapy is the abbreviation of chemotherapeutic drug therapy, which achieves the purpose of treatment by using chemotherapeutic drugs to kill cancer cells. Chemotherapy is currently one of the most effective means of treating cancer, together with surgery and radiotherapy, it is also known as the three major means of cancer treatment. Surgery and radiotherapy are local treatments, which are only effective on the tumor at the treatment site, and are difficult to effectively treat potential metastatic lesions and lesions that have already undergone clinical metastasis. Chemotherapy is a means of systemic treatment. No matter what route of administration is adopted, chemotherapy drugs will spread throughout most of the organs and tissues of the whole body alo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61P7/00A61K31/045
CPCA61K9/0014A61K31/045A61K36/268A61K36/284A61K36/39A61K36/43A61K36/481A61K36/486A61K36/54A61K36/815A61K36/8969A61K2236/331A61K2236/39A61K2300/00
Inventor 王笑民富琦杨国旺张怡梁姗姗徐咏梅
Owner BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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