Traditional Chinese medicinal composition for treating Alzheimer's disease as well as preparation method and application thereof

A technology for Alzheimer's disease and a composition, applied in the field of traditional Chinese medicine, can solve problems such as health hazards of Alzheimer's disease patients, achieve huge economic and social benefits, broad application prospects, and obvious effects.

Inactive Publication Date: 2018-07-20
QIQIHAR MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, many drugs at home and abroad can treat Alzheimer's disease, such as acetylcholinesterase (AChE) inhibitors, antioxidants, anti-neuronal cell apoptosis drugs, estrogen, neurotrophic factors, antipsychotic drugs, Aβ drugs, etc., but many drugs have a certain degree of adverse reactions, which will bring harm to the health of patients with Alzheimer's disease. Therefore, it is very important to actively explore drugs for the treatment of Alzheimer's disease with small adverse reactions and very effective

Method used

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  • Traditional Chinese medicinal composition for treating Alzheimer's disease as well as preparation method and application thereof
  • Traditional Chinese medicinal composition for treating Alzheimer's disease as well as preparation method and application thereof
  • Traditional Chinese medicinal composition for treating Alzheimer's disease as well as preparation method and application thereof

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Effect test

Embodiment 1

[0058] The preparation of embodiment 1 Chinese medicine composition

[0059] The traditional Chinese medicine composition is composed of the following raw materials by weight: 12g of black sesame, 12.5g of Chushi, 20g of wolfberry leaves, 25g of Dendrobium candidum, 19.5g of blue cloth, 12g of panlong ginseng, 4.5g of Huazhou orange red, and scallion white 7.5g, bergamot 6g, styrax 0.65g, ghost arrow feather 10g, brassica 8.25g, yellow flower water lotus 22.5g, Trichosanthes 12g, deer 22.5g.

Embodiment 2

[0060] The preparation of embodiment 2 Chinese medicine composition

[0061] The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: 10g of black sesame, 15g of mulberry fruit, 16g of wolfberry leaf, 25g of Dendrobium candidum, 15g of blue cloth, 15g of panlong ginseng, 5g of Huazhou orange red, 6g of scallion, 5g of bergamot, 1g of styrax, 8g of ghost arrow feather, 8g of brassica, 20g of yellow lotus, 12g of Trichosanthes, and 20g of deer's grass.

Embodiment 3

[0062] The preparation of embodiment 3 Chinese medicine composition

[0063] The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: 15g of black sesame, 10g of mulberry, 25g of wolfberry leaves, 20g of Dendrobium candidum, 25g of blue cloth, 10g of Panlong ginseng, 3g of Huazhou orange, 10g of scallion, bergamot 8g, styrax 0.5g, ghost arrow feather 5g, brassica 5g, yellow lotus 25g, Trichosanthes 10g and deer bit grass 25g.

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating the Alzheimer's disease as well as a preparation method and application thereof. The traditional Chinese medicinal composition selects a traditional Chinese medicinal composition prepared from the national drugs of semen sesami nigri, fructus broussonetiae, folium ilicis cornutae, herba dendrobii officinale, herba gei, radix et herba sprianthis sinensis, exocarpium citri grandis, bulbus allii macrostemi, fructus citri sarcodactylis, styrax, ramulus euonymi, semen brassicae campestris, radix polygalae fallacies, fructus trichosanthis and herba pyrolae; the treatment to a mouse model suffered from the Alzheimer's disease is developed; shown by a result, the traditional Chinese medicinal composition provided by the invention has obvious comprehensive treatment effect on the Alzheimer's disease and moreover has no side effect. The traditional Chinese medicinal composition is proposed to provide a novel technical means for the treatment of the Alzheimer's disease; the huge economic benefit and social benefit can be generated, and the application prospect is quite wide.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation method and application, in particular to a traditional Chinese medicine composition for treating Alzheimer's disease, its preparation method and application. The invention belongs to the technical field of traditional Chinese medicine. Background technique [0002] Alzheimer's disease (Alzheimer's disease) is a clinically common senile disease, and its morbidity, prevalence and mortality are increasing year by year. In recent years, patients with Alzheimer's disease have brought great mental and economic burdens to the family, society and the country. It has become the second-highest death rate in many foreign countries after cardiovascular and cerebrovascular diseases, tumors and strokes. Therefore, it is particularly important to actively and effectively treat Alzheimer's disease. [0003] It has been confirmed that in Alzheimer's disease, a large amount of β-am...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P25/28
CPCA61K36/185A61K36/31A61K36/37A61K36/428A61K36/60A61K36/69A61K36/73A61K36/752A61K36/8962A61K36/898A61K36/8984A61K2236/31A61K2236/39A61K2300/00
Inventor 费洪新吴树亮张晓杰张英博
Owner QIQIHAR MEDICAL UNIVERSITY
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