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Identification method of traditional Chinese medicine preparation for treating synovitis

A technology for traditional Chinese medicine preparations and synovitis, which is applied in the identification field of traditional Chinese medicine preparations, can solve the problems of poor correspondence of medicinal materials, many times of unfolding, and low content of finished products, and achieves good application value, product quality control, and clear chromatographic spots.

Active Publication Date: 2018-08-24
HENAN LUOZHENG PHARMA FACTORY
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after in-depth research on its many batches of products, it was found that its thin-layer identification method has deficiencies, which are shown in: ①In the identification of turmeric, because curcumin is insoluble in water, it is difficult to dissolve curcumin by water extraction, so The content in the finished product is small, it is difficult to detect, the reproducibility is poor, and it is easy to cause false negatives; ②In the identification of Bupleurum, the background interference of the sample is large, the separation ability of the developing agent for the main spots is poor, the correspondence with the medicinal materials is poor, and the number of developments is too many , time-consuming; ③In the identification of Dipsacus, the background interference of the sample is large, and the number of developments is large, which is time-consuming; ④In the identification of Angelica, the polarity of the developing agent is too large, and the R of the main spot of the chromatogram f The value is too large, and the main spots are not concentrated; ⑤ There is no identification of the contained Astragalus, Gentiana, and Achyranthes bidentata
[0006] The above deficiencies in the prior art have seriously affected the quality control and result judgment of the product

Method used

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  • Identification method of traditional Chinese medicine preparation for treating synovitis
  • Identification method of traditional Chinese medicine preparation for treating synovitis
  • Identification method of traditional Chinese medicine preparation for treating synovitis

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Embodiment Construction

[0045] Below in conjunction with embodiment, the present invention is described in detail.

[0046] First, the preparation of a Chinese medicine preparation for treating synovitis (hereinafter referred to as knee Yue granules) described in this application:

[0047] [Prescription] Astragalus 1875 g, Gentiana 937.5 g, Angelica 625 g, Dipsacus 625 g, Moutan bark 625 g, Bupleurum 625 g, turmeric 750 g, Sangji 750 g, Mianzi 937.5 g, Achyranthes bidentata 375 g, Licorice 187.5 g.

[0048] [Preparation method] Add 10 times the weight of water to decoct the above eleven flavors respectively for three times, each time for 1 hour, combine the decoction, filter, concentrate the filtrate to a relative density of 1.18-1.22 (80 ℃), let cool to 40 ℃, add ethanol to make the alcohol content reach 50% (volume concentration), stir well, let stand for 24 hours, take the supernatant, and set aside. Add an appropriate amount of 50% ethanol (volume concentration) to the dregs, stir well, let sta...

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Abstract

The invention provides an identification method of a traditional Chinese medicine preparation for treating synovitis. The traditional Chinese medicine preparation is of granules prepared from 11 traditional Chinese medicines including radix astragali, radix gentianae macrophyllae, radix angelicae sinensis, radix dipsaci, cortex moutan, radix bupleuri, rhizoma curcumae longae, herba taxilli, rhizoma dioscoreae septemlobae, radix cyathulae and liquorice root. According to the identification method provided by the invention, an existing identification method is improved, an identification methodof the radix bupleuri, the radix dipsaci and the radix angelicae sinensis is improved and an identification method of the radix astragali seu hedysari, the radix gentianae macrophyllae and the radix cyathulae is increased; the identification of the rhizoma curcumae longae is deleted; an operation method is simple and color spectrum spots are clear; the identification method is negative and has nointerference, has strong specificity and good repeatability, can control the quality of a product better and has good application value.

Description

technical field [0001] The invention relates to a method for identifying a traditional Chinese medicine preparation, in particular to a method for identifying a traditional Chinese medicine preparation for treating synovitis, and belongs to the technical field of quality control of traditional Chinese medicine preparations. Background technique [0002] Good drug quality is the basis and premise for exerting the curative effect of drugs, and qualitative identification is an important part of identifying the authenticity of drugs and ensuring the quality of drugs. Traditional Chinese medicine preparations generally have many medicinal flavors and complex ingredients. Since ancient times, there has been a saying that "pills, powders and ointments, gods can't distinguish them", which shows that it is difficult to identify Chinese medicine preparations. Moreover, most of the modern Chinese medicine preparations have been extracted and purified, and most of the medicinal material...

Claims

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Application Information

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IPC IPC(8): G01N30/90
CPCG01N30/90
Inventor 赵新杰杜志谦武爱玲夏华玲丁震江海肖孙实张宏都
Owner HENAN LUOZHENG PHARMA FACTORY
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