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Fast directional biodegradation hemostatic clamp and preparation method thereof

A technology of biodegradable and hemostatic clips, which is applied in the fields of pharmaceutical formulations, manufacturing tools, welding equipment, etc. It can solve the problems of affecting image inspection, slow degradation rate of pure iron metal, and failure to solve the degradation of magnesium metal.

Active Publication Date: 2018-09-14
烟台浩忆生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, titanium clips have some disadvantages: First, they cause inflammatory reactions, because titanium clips will not be degraded after being implanted in the body, and will exist permanently. Complications; second, it affects postoperative imaging examinations, because titanium metal absorbs X-rays and affects ultrasound. When patients undergo postoperative CT, B-ultrasound and other examinations, titanium clips will interfere with the images of surrounding organs and affect the doctor's diagnosis; Third, it is conductive. If the electrocoagulator accidentally touches the titanium clip, it will burn the surrounding tissue and increase the risk of surgery. Fourth, it will increase the physical and economic burden of the patient. It causes psychological burden to the patient, but taking it out through a second operation will also increase the cost of the operation
There are still some problems in the technical solution of this patent: first, its technical solution does not solve the degradation problem of magnesium metal
The hemostatic clip is U-shaped and has antibacterial function, but the problem of slow degradation rate of pure iron metal has not been solved

Method used

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  • Fast directional biodegradation hemostatic clamp and preparation method thereof
  • Fast directional biodegradation hemostatic clamp and preparation method thereof
  • Fast directional biodegradation hemostatic clamp and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A rapid and directional biodegradable hemostatic clip is prepared by using degradable pure iron plate, and the specific steps are as follows:

[0036] The first step is to select pure iron plates with an iron content of more than 99.99% as raw materials.

[0037] In the second step, the plate is processed by laser cutting to obtain the required hemostatic clip. The structure is as attached image 3 As shown, the blood vessel 1, the upper arm of the hemostatic clip 2, the lower arm of the hemostatic clip 3, the tail structure 4, the upper arm locking hook 5, the lower arm locking hook 6, the horizontal stripes 7, and the fixing structure 8. The total length of the hemostatic clip is 10 mm, the width is 1 mm, and the thickness is 2 mm. The diameter of the inner arc of the tail is 0.8 mm, and the diameter of the outer arc is 2 mm. The opening angle of the hemostatic clip is 60°. The width of the horizontal stripes is 0.1mm, forming an angle of 60° with the upper and lower...

Embodiment 2

[0043] Adjust the modification parameters in Step 3 to: power: 10w, scanning interval: 60 μm, scanning speed: 800 mm / s, and modification treatment 5 times. Other step parameters are the same as in Example 1.

[0044] The energy spectrum analysis of the obtained laser-modified surface of the hemostatic clip shows that the laser-modified surface of the hemostatic clip contains 4.6% Fe 2 o 3 .

Embodiment 3

[0046] Adjust the modification parameters in Step 3 to: power: 15w, scanning interval: 80 μm, scanning speed: 1000 mm / s, and modification treatment 10 times. Other step parameters are the same as in Example 1.

[0047] The energy spectrum analysis of the laser-modified surface of the obtained hemostatic clip shows that the laser-modified surface of the hemostatic clip contains 6.8% Fe 2 o 3 .

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Abstract

The invention belongs to the field of an implanted medical appliance product, and particularly relates to a fast directional biodegradation hemostatic clamp and a preparation method thereof. The outersurface and the side surfaces of the hemostatic clamp are subjected to laser surface modification treatment; the outer surface and the side surfaces of the hemostatic clamp have laser modification layers after the laser surface modification; the degradation speed is higher than that at the inner side; the directional degradation from the outside to the inside can be realized.

Description

technical field [0001] The invention belongs to the field of implantable medical device products, and in particular relates to a rapid and directional biodegradable hemostatic clip and a preparation method thereof. Background technique [0002] Clinically, when performing laparoscopic surgery, doctors will ligate active bleeding blood vessels near the surgical site that cannot be sutured or needn't be sutured to avoid bleeding during and after surgery. There are two types of closure techniques at present: first, suturing the required ligation and closure with sutures, but the operation time is long and the operation is difficult; second, surgical hemostatic clips are used to clamp the bleeding blood vessels, which is relatively easy to operate and has a better hemostatic effect. it is good. Commonly used hemostatic clip materials are mainly non-degradable metal hemostatic clips and absorbable polymer hemostatic clips. [0003] Hemostatic clips made of non-degradable metal ...

Claims

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Application Information

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IPC IPC(8): A61L31/02A61L31/14B23K26/352
CPCA61L31/022A61L31/14A61L2400/18B23K26/352
Inventor 毕衍泽安红娟
Owner 烟台浩忆生物科技有限公司
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