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A pet-mri maximum a posteriori joint reconstruction method
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A PET-MRI and maximum a posteriori technology, applied in image enhancement, image analysis, instrumentation, etc., can solve problems such as increasing image artifacts and affecting image quality
Active Publication Date: 2022-02-01
SOUTHERN MEDICAL UNIVERSITY
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However, the features of PET and MRI images obtained by level set prior reconstruction appear to be interlaced, which increases image artifacts and seriously affects image quality.
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Embodiment 1
[0056] Pet-MRI maximum subtronom in combination reconstruction method, such as figure 1 , 2 , 4 and 5, including the following steps:
[0057] Step 1, collect the PET data and MRI data of the object;
[0058] Step Second, the mathematical statistical model of PET-MRI joint reconstruction is constructed by step a collected PET data and MRI data;
[0059] Step 3, in the mathematical statistical model of step II, use the correction design of the PET image to be reconstructed and the correlation design of the MRI image to be reconstructed;
[0060] Step 4, combined with the cross-crossed cross-priority model, using the maximum post-test method to jointly rebuild the mathematical statistical model of step two, obtain an optimized equation with constrained target functions;
[0061] Step 5. The optimization equation obtained by the constrained target function obtained by the step four is used to synchronize the PET reconstruction image and the MRI reconstruction image.
[0062] Step, on...
Embodiment 2
[0101] A PET-MRI maximum subtronom in combination reconstruction method, and other features are the same as in Example 1, and the acquisition target of this implementation is the brain, PET and MRI reconstruction images. image 3 and 6 Indicated.
[0102] In order to verify the effect of the method of the present invention, Image 6 The brain PET and MRI reconstruction images that are jointly reconstructed by PET and SPIRAL 20 underwnamp the PET and Spiral 20 are displayed by different methods, and the priori based on joint total variation (JTV) and linear levels (LPLS) proposed by MJEHRHARDT et al. Compared with the maximum subtrial reconstruction method, the PET and MRI images reconstructed by the method of the present invention are more clear, can synchronize the PET and MRI images, suppress PET image noise, reduce MRI artifact, and improve the quantization level of reconstruction images. .
[0103] Table 2 gives an optimized parameter α, β, γ, μ u Μ v , Η u , Η v After evaluatin...
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Abstract
A PET‑MRI maximum posterior joint reconstruction method, comprising the steps of: one, collecting PET data and MRI data of an object; two, constructing a mathematical statistical model of PET‑MRI joint reconstruction; three, in the mathematical statistical model, using the Reconstruct the correlation of PET and MRI images and design a cross prior model; 4. Combine the cross prior model of PET and MRI designed in step 3, and use the maximum a posteriori method to combine the mathematical statistics model of PET and MRI images constructed in step 2 Reconstruction to obtain an optimization equation with a constrained objective function; fifth, perform iterative calculation on the optimized equation with a constrained objective function obtained in step 4, and simultaneously obtain PET and MRI reconstructed images. The invention can simultaneously reconstruct PET and MRI images, suppress PET image noise, reduce MRI artifacts, improve the quantization level of reconstructed images, and better assist clinical diagnosis.
Description
Technical field [0001] The present invention relates to the field of PET and MRI imageprocessing of medical imaging, and more particularly to a Maximum sub-sub-reconstruction method of PET-MRI. Background technique [0002] MRI provides soft tissuehigh resolution structure information, and PET provides human metabolic function information. Traditionally, the reconstruction of PET and MRI is independent, or the PET reconstruction is guided by MRI structural similarities. [0003] With the emergence and development of the PET-MRI system, the concept of PET-MRI joint reconstruction is proposed. In recent years, PET-MRI integrated systems have continued to develop and are gradually applied to the clinic. The PET-MRI integrated system can accurately dissective PET with MRI, reducing the radiationdose relative to PET / CT, and reduces the damage to the human body. The PET-MRI integrated system can simultaneously collect PET and MRI data to obtain high-level PET and MRI data. The qua...
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