Microfluid flow online adjusting device and detection method
A technology of an adjustment device and a detection method, which is applied in the field of microfluidics, can solve the problem that the ideal output flow of a pressure driving device is difficult to accurately calculate, and achieves the effects of online rapid detection, high measurement accuracy and stable adjustment
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
specific Embodiment approach 1
[0025] Specific implementation mode one: the following combination figure 1 with figure 2 Describe this embodiment, the microfluid flow rate online adjustment device and detection method described in this embodiment, it consists of a gas supply source 1, a pressure reducing valve 2, a proportional pressure valve 3, a first liquid container 4, a valve 5, a first pressure A sensor 6, a second pressure sensor 7, a microfluidic channel 8, a microfluidic chip 9, a second liquid container 10, a weighing instrument 11 and a microprocessor 12 are formed. in:
[0026] The gas inlet of the pressure reducing valve 2 is communicated with the compressed air outlet of the gas supply source 1, and the gas outlet of the pressure reducing valve 2 is communicated with the gas inlet of the proportional pressure valve 3;
[0027] The gas outlet of the proportional pressure valve 3 communicates with the gas inlet of the first liquid container 4, and the liquid outlet of the first liquid contain...
specific Embodiment approach 2
[0037] Specific implementation mode two: the following combination figure 2 This embodiment will be described, and this embodiment will further describe the first specific embodiment. In order to ensure that the microfluid flow has a linear relationship with the pressure difference at both ends of the microfluid channel 8 (the microfluid flow Q = scale factor K × differential pressure ΔP ), to realize the on-line accurate detection of microfluidic flow, the microfluidic channel 8 adopts the structure of PTFE round tube, and the length of the round tube is required L with inner diameter d The ratio is greater than 20:1, and the Reynolds number Re <1.0 of the microfluid flow is satisfied inside the circular tube, and the microfluid is in a laminar flow state.
[0038] In this embodiment, the inner diameter of the PTFE round tube d The range of change is 0.1 ~ 1.0 mm, the length of PTFE round tube L The variation range of 10.0 ~ 40.0 mm, according to the microfluidic flo...
specific Embodiment approach 3
[0039] Specific implementation mode three: the following combination image 3The present embodiment will be described, and the specific embodiment 1 will be further described in this embodiment. In order to realize online stable regulation of the microfluidic flow rate, the first pressure sensor 6 and the second pressure sensor 7 respectively measure the inlet and outlet pressures of the microfluidic channel 8 to obtain the pressure difference at both ends of the microfluidic channel 8 and feed it back to the microprocessor 12, The control signal is output by the microprocessor 12 to change the gas control pressure of the proportional pressure valve 3 and adjust the microfluidic flow online.
[0040] In this embodiment, the online adjustment time of the microfluid flow is less than 0.5 s, and the online adjustment accuracy of the microfluid flow reaches 0.1%.
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More