Povidone-iodine solution and preparation method thereof

A technology of povidone-iodine and solution, which is applied in the directions of pharmaceutical formulations, active ingredients of iodine compounds, and medical preparations of non-active ingredients, etc., can solve the problem that the skin heat and moisture are easily taken away, the skin of cow teats loses elasticity, and the medicated bath is affected. It can prevent and treat dairy cow mastitis, save labor and medication costs, and have no toxic and side effects.

Active Publication Date: 2018-10-30
FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the dairy cow medicated baths currently on the market have a high water content, which makes the medicated bath drip after infiltrating the cow’s teats, does not adhere to the cow’s teats, or is easily rubbed off by the cow’s bed, which greatly affects the effect of the post-medication bath and causes waste of medication.
[0003] It can be seen from the article "Development and Application Effect Observation of Cow Nipple Liquid Protective Film" published by Zhou Qingmin, Heilongjiang Veterinary Science Research Institute, etc., that although its prescription can be made into a film-forming povidone-iodine solution, it us

Method used

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  • Povidone-iodine solution and preparation method thereof
  • Povidone-iodine solution and preparation method thereof
  • Povidone-iodine solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～3

[0034] A kind of povidone-iodine solution, by every 100g solution, its raw material composition sees the following table 1.

[0035] The formula table of table 1 embodiment 1~3

[0036] Raw materials (unit g)

Example 1

Example 2

Example 3

potassium iodate

0.036

0.18

0.36

potassium iodide

0.32

1.6

3.2

dodecyl dimethyl amine oxide

0.5

1

1.5

pvp

1

1

1

PVA

2

2

2

Polyurethane 35

5

5

5

sodium alginate

0.5

0.5

0.4

Propylene Glycol

2

2

2

citric acid

0.2

0.2

0.2

Sodium citrate

0.4

0.4

0.4

water

margin

margin

margin

[0037] Its preparation method is as follows:

[0038] 1. Put water into the preparation tank, start the stirring device, put citric acid and film-forming agents PVP, PVA, polyurethane 35, and sodium alginate in sequence, start steam heating, raise the temperature to 80°C t...

Embodiment 4

[0043] Example 4 is basically the same as Example 2, except that the surfactant used is different, specifically, 1 g of fatty alcohol polyoxyethylene ether is used instead of 1 g of dodecyldimethylamine oxide.

Embodiment 5

[0045] Example 5 is basically the same as Example 1, except that the plasticizer used is different, specifically, 2 g of phthalates are used instead of 2 g of propylene glycol.

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Abstract

The invention relates to a povidone-iodine solution and a preparation method thereof. Each 100g of the povidone-iodine solution is mainly prepared from, by weight, 0.02-0.5g of potassium iodate, 0.1-3.5g of potassium iodide, 0.5-5g of PVP, 1-5g of polyethylene glycol, 2-10g of polyurethane, 0.1-5g of sodium alginate, 0.2-0.5g of organic acid, 0.5-3.5g of surfactant, 1-5g of plasticizer and the balance of water and pH regulator. The povidone-iodine solution is safe, reliable, high in stability and good in film forming effect, a film formed by the solution is not high in toughness and less proneto shedding, efficacy is lasting, antibacterial effect is ensured, a lot of labor and medication cost can be saved, and the solution is suitable for extensive dairy cow farms.

Description

technical field [0001] The invention relates to the technical field of veterinary disinfectants, in particular to a povidone-iodine solution and a preparation method thereof. Background technique [0002] In the dairy farming industry, dairy cow mastitis has always been a problem for dairy farmers, and it is also one of the main causes of economic losses for dairy farmers. Every time before and after milking, the nipples of cows should be disinfected to prevent and control the occurrence of mastitis in cows, especially after dipping plays an important role in preventing mastitis in cows. Most of the dairy cow medicated baths currently available in the market have a high water content, which makes the medicated bath drip after infiltrating the cow's teats, does not adhere to the cow's teats, or is easily rubbed off by the cow's bed, which greatly affects the effect of the post-medication bath and causes waste of medication . [0003] It can be seen from the article "Develop...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K33/18A61K31/79A61K47/32A61K47/34A61K47/36A61K47/12A61K47/10A61P15/14A61P31/02A61P31/04
CPCA61K9/0041A61K9/08A61K31/79A61K33/18A61K47/10A61K47/12A61K47/32A61K47/34A61K47/36A61P15/14A61P31/02A61P31/04A61K2300/00
Inventor 徐奇清周淑贞张庆黄海青聂姣
Owner FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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