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Thrombus induction experimental device

An experimental device and thrombus technology, applied in medical science, veterinary instruments, veterinary surgery, etc., can solve problems such as unavoidable damage to the smooth muscle layer, and achieve the effects of accurate and controllable damage degree, avoidance of damage, and reliable experimental results.

Inactive Publication Date: 2018-11-06
青岛市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of the above situation, in order to overcome the defects of the prior art, the present invention provides an experimental device for thrombus induction, which effectively solves the problem that the current experimental device cannot avoid damage to the smooth muscle layer

Method used

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Embodiment Construction

[0015] The specific implementation manners of the present invention will be described in further detail below in conjunction with the accompanying drawings.

[0016] Depend on Figure 1 to Figure 3 Provided, the present invention includes a housing 1, the cavity inside the housing 1 is cylindrical, the housing 1 is provided with a liquid injection hole 2 communicating with the cavity, and a fixed partition 3 and a movable partition are installed in the cavity. The partition 4, the fixed partition 3 and the movable partition 4 are all arranged radially along the cavity, the movable partition 4 can rotate back and forth around the axis of the cavity, the fixed partition 3 and the movable partition 4 separate the cavity It is two separately closed fan-shaped chambers 5, and the rotation of the movable partition 4 can change the volume of the two fan-shaped chambers 5; the side walls of the housing 1 on both sides of the fixed partition 3 are respectively provided with a cavity co...

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Abstract

The invention relates to a thrombus induction experimental device and effectively solves the problem of failure in avoiding of smooth muscle layer injuries in application of an existing experimental device. The technical scheme for solution includes that the thrombus induction experimental device comprises a shell with an internal cylindrical cavity, a fixed partition plate and a moving partitionplate are mounted in the cavity, the moving partition plate is capable of rotationally reciprocating forwards and backwards along the axis of the cavity, the cavity is partitioned into two closed sector-shaped cavities by the fixed partition plate and the moving partition plate, the moving partition plate rotates to change volumes of the two sector-shaped cavities, and each sector-shaped cavity iscommunicated with a first spiral needle. By alternate volume changes of the two sector-shaped cavities, normal saline in the sector-shaped cavities can be pushed to reciprocate, particles are injected into the blood vessel, and the normal saline flows to drive the particles to scrape the intima of the blood vessel. The thrombus induction experimental device has advantages of accuracy and controllability of injury degree, effectiveness in avoiding of the smooth muscle layer injuries, simplicity in operation, low injuries to experimental subjects, few interference factors and high reliability of experimental results.

Description

technical field [0001] The invention relates to the field of medical experiment equipment, in particular to a thrombus induction experiment device. Background technique [0002] Cardiovascular and cerebrovascular diseases are the number one killer threatening human health. Atherosclerosis is the main cause of cardiovascular and cerebrovascular diseases. Intimal injury is an important pathogenesis of atherosclerotic diseases. In related experimental studies, researchers need to artificially damage the vascular intima of experimental animals, and then conduct research on the mechanism of vascular-related diseases. [0003] At present, the balloon method is mainly used to damage the intima of the blood vessel, that is, the balloon with a cavity is placed in the blood vessel cavity of the experimental animal, and then water is injected into the cavity of the balloon through a catheter connected with the cavity to make the balloon expand. When the balloon is inflated to the maxi...

Claims

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Application Information

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IPC IPC(8): A61D1/00A61D7/00
CPCA61D1/00A61D7/00
Inventor 张大伟程珊王琳赵越
Owner 青岛市中医医院
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