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An experimental device for animal vascular intima injury

A technology of vascular intima and experimental equipment, which is applied in veterinary surgery, medical science, veterinary instruments, etc., can solve the problem of unavoidable smooth muscle layer damage, achieve precise and controllable damage, reliable experimental results, and small damage Effect

Active Publication Date: 2019-12-17
XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of the above situation, in order to overcome the defects of the prior art, the present invention provides an experimental device for animal vascular intima injury, which effectively solves the problem that the current experimental device cannot avoid damage to the smooth muscle layer

Method used

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  • An experimental device for animal vascular intima injury
  • An experimental device for animal vascular intima injury
  • An experimental device for animal vascular intima injury

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Experimental program
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Embodiment Construction

[0016] The specific implementation manners of the present invention will be described in further detail below in conjunction with the accompanying drawings.

[0017] Depend on Figure 1 to Figure 4 Given, the present invention comprises a suction unit, and the suction unit comprises a piston cylinder 1, a first piston 2 and a second piston 3 that can slide left and right are installed in the piston cylinder 1, and the first piston 2 is on the left, and the first piston 2 A horizontal guide rod 4 is installed on the right end surface of the guide rod 4, the right end of the guide rod 4 passes through the second piston 3 and can slide relative to the second piston 3, the right end of the guide rod 4 is provided with a flange, and the two pistons can be pulled mutually through the flange, When the first piston 2 and the second piston 3 are located at the rightmost positions in their respective strokes, the cavities on the left and right sides of the first piston 2 have the same v...

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Abstract

The invention relates to an animal blood vessel intima damage experiment device. By means of the device, the problem in the prior art that an existing experiment device cannot prevent the smooth muscle layer from being damaged is effectively solved. According to the technical scheme of the invention, the device comprises two sets of suction units, a first needle head, a second needle head and a connecting pipeline. The first needle head is in a spiral shape. The two sets of suction units can alternately inject the normal saline into a blood vessel and suck the normal saline out of the blood vessel through the first needle head, so that a spiral water flow is formed in the blood vessel. Particles can be injected into the blood vessel by the second needle head. The spiral water flow can drive the particles to flow in the blood vessel so as to scratch the inner membrane of the blood vessel. According to the invention, the damage degree is accurate and controllable, and the damage of a smooth muscle layer can be effectively avoided. The operation is simple, and the damage to an experimental object is small. The interference factor is small, and the experimental result is more reliable.

Description

technical field [0001] The invention relates to the field of medical experiment equipment, in particular to an animal vascular intima injury experiment device. Background technique [0002] Cardiovascular and cerebrovascular diseases are the number one killer threatening human health. Atherosclerosis is the main cause of cardiovascular and cerebrovascular diseases. Intimal injury is an important pathogenesis of atherosclerotic diseases. In related experimental studies, researchers need to artificially damage the vascular intima of experimental animals, and then conduct research on the mechanism of vascular-related diseases. [0003] At present, the balloon method is mainly used to damage the intima of the blood vessel, that is, the balloon with a cavity is placed in the blood vessel cavity of the experimental animal, and then water is injected into the cavity of the balloon through a catheter connected with the cavity to make the balloon expand. When the balloon is inflated...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61D1/00
CPCA61D1/00
Inventor 张大伟程珊王琳赵越
Owner XINXIANG MEDICAL UNIV
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