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A device for manipulating magnetic nanomaterials to improve the efficiency of thrombolysis in veins

A magnetic nano-thrombolysis technology, which is applied in medical science, surgery, chemical library problems, etc., can solve problems such as the limitation of thrombolysis efficiency, and achieve the effects of reducing the risk of bleeding, promoting diffusion, and rapidly dissolving

Inactive Publication Date: 2021-01-19
HUAZHONG UNIV OF SCI & TECH
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Problems solved by technology

[0003] Aiming at the above defects or improvement needs of the prior art, the present invention provides a device for manipulating magnetic nanomaterials to increase the thrombolysis efficiency in veins, thereby solving the technical problem that the thrombolysis efficiency of intravenous thrombolysis with urokinase has limitations

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  • A device for manipulating magnetic nanomaterials to improve the efficiency of thrombolysis in veins

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Embodiment Construction

[0018] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention. In addition, the technical features involved in the various embodiments of the present invention described below can be combined with each other as long as they do not constitute a conflict with each other.

[0019] The terms "first", "second", "third" and "fourth" in the specification and claims of the present invention are used to distinguish different objects, rather than to describe a specific order.

[0020] The invention provides a device for manipulating magnetic nanomaterials to increase the thrombolysis efficiency in veins. The magnetic nanomaterials are firstly mixed with urokinase to form ...

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Abstract

The invention discloses a device for improving the efficiency of thrombolysis in veins by controlling a magnetic nanometer material, and belongs to the technical field of magnetic nanometer materials.By mixing magnetic nanometer particles with a urokinase solution, the magnetic nanometer particles is made to form micro-aggregate lines under the action of a magnetostatic field, and then under thecontrol of a spatial rotation field, the micro-aggregate lines do rotation movement, and the rotation movement causes the surrounding flow field to form eddy current, so that urokinase is helped to bediffused into the surfaces of thrombi, and dissolution of the thrombi is accelerated. The device has the advantages that the structure is simple, and the operation is convenient, and the efficiency of thrombolysis in the veins is helped to be quickly improved.

Description

technical field [0001] The invention belongs to the technical field of magnetic nano-materials, and more specifically relates to a device for manipulating magnetic nano-materials to improve thrombolytic efficiency in veins. Background technique [0002] Intravenous thrombolysis with urokinase is still the main choice for the clinical treatment of thrombotic diseases. However, in order to achieve the dredging of blood vessels and promote the normal delivery of oxygen and nutrients to tissues or organs, large doses of thrombolytic drug injections are often required clinically. Entering blood vessels to increase the amount of thrombus contact is affected by the non-specificity of drugs. Drugs simultaneously activate plasminogen in the blood and lead to a decrease in other coagulation factors, thereby increasing the rate of bleeding complications. Especially in blood vessels severely blocked by thrombus, urokinase thrombolysis can only reach the thrombus surface through slow dif...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C40B99/00A61B17/22H01F5/00
CPCA61B17/22A61B2017/22084H01F5/00
Inventor 刘晓军李千卢珍章明
Owner HUAZHONG UNIV OF SCI & TECH
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