Device and method for detecting bilirubin for sclera imaging

Abstract

The invention provides a device and a method for detecting bilirubin for sclera imaging. A collecting lens, a diaphragm, a first optical lens and a transflective lens are placed from a lighting lightsource to a sclera in sequence; light is deflected by 90 degrees after passing through the transflective lens; and in the direction, a second optical lens, a trapezoidal prism, a third optical lens, aCCD and an external data processor are placed outwards from the transflective lens in sequence. According to the method, the thickness of the sclera is determined by measuring the brightness values of different points on the sclera, and the concentration numerical value of the bilirubin is determined by solving equations through the imaging brightness ratio under three wavelengths.

Description

technical field [0001] The invention relates to a bilirubin detection device and method for sclera imaging, which belongs to the field of optical detection, and more specifically detects the optical scattering properties of human eyes. Background technique [0002] At present, the detection of bilirubin is mainly divided into invasive detection and non-invasive detection. The invasive test is the serum test method. The collected blood is centrifuged in a centrifuge, the supernatant is separated, and then determined by chemical methods. Invasive testing has high accuracy, but it will cause wounds and pain, the testing time is long, and it is difficult for newborns to collect blood. [0003] Non-invasive detection is mainly percutaneous optical detection method. Among them, the dual-wavelength method considers the spectral characteristics of hemoglobin and bilirubin, selects 460nm and 550nm spectral analysis, removes the influence of hemoglobin on the detection of bilirubin,...

AI Technical Summary

Problems solved by technology

This method has a slight improvement in accuracy compared to the dual-wavelength method, but the improvement is not particularly ideal due to too much noise in the skin

At the same time, the complexity of the measurement method increases the cost and the complexity of data processing, which is not conducive to the promotion of the instrument.

In addition, due to the different skin parameters of adults, the current non-invasive percutaneous optical detection method is basically only used for neonatal bilirubin detection, and its scope of application is greatly limited by age.

Images