A Chinese medicinal composition for treating acne and cosmetic
A composition and acne-removing technology, which are applied in the directions of cosmetics, cosmetic preparations, cosmetic preparations, etc., can solve the problems of damaged skin tissue structure, unsatisfactory treatment effect, poor treatment effect, etc. The effect of repairing skin barrier and regulating skin immunity
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Embodiment 1~10
[0031] Embodiments 1-10 are anti-acne essence, and its formula is shown in Table 1. The preparation method of the anti-acne essence described in Examples 1-10 comprises the following steps:
[0032] (1), add water, glycerol, butanediol, small molecule sodium hyaluronate, purslane extract, dipotassium glycyrrhizinate and 10-hydroxydecanoic acid into the container, heat up to 75-80°C, and Stir at 1500r / min until evenly mixed, keep warm for 30min to sterilize for later use, and record it as mixed solution A.
[0033] (2) When the mixture A is cooled to 45-55°C, add hydroxyphenylpropionamide benzoic acid, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, green tea extract, and Glycyrrhiza glabra root extract Extract, chamomile flower extract and rosemary extract, stir evenly at 1500r / min, and record it as mixed solution B.
[0034] (3) When the temperature of the mixed liquid B is lowered to below 40°C, add the kava pepper extract...
Embodiment 11
[0039] Product safety evaluation (human skin patch test)
[0040] Number of subjects: 60 people; age between 20 and 50; health status: subjects have healthy skin, no history of skin allergies, and meet the voluntary selection criteria for subjects. In groups, 10 groups, 6 people in each group.
[0041] Patch method: select a qualified patch tester, drop about 0.020g ~ 0.025g of the test substance into the patch tester in a closed patch test method, and stick the special tape for external use on the back of the subject. After 24 hours Remove the test substance, observe the skin reaction 0.5, 6, 12, 24, and 48 hours after removal, and record the results according to the skin reaction grading standard in the "Hygienic Standards for Cosmetics".
[0042] test results:
[0043]The results of the human skin patch test showed that the subjects in each group passed the patch test of the acne-removing essence milk in Examples 1 to 10, and observed skin reactions at 0.5, 6, 12, 24, and...
Embodiment 12
[0045] Antibacterial test
[0046] experiment method:
[0047] Refer to the National Standard of the People's Republic of China GB15797-2002 "Hygienic Standards for Disposable Hygienic Products" in Appendix C4 "Bacteriostatic Performance Test Method for Dissolution Antibacterial (Inhibitory) Products".
[0048] Tested strains:
[0049] Staphylococcus aureus ATCC6538; Pseudomonas aeruginosa ATCC 9027; Escherichia coli ATCC 8739; Candida albicans ATCC10231; Microsporum furfur; Propionibacterium acnes.
[0050] Media and culture conditions:
[0051] Ordinary nutrient agar medium (cultivated at 37°C for 48 hours, used for the cultivation of Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli); Sabouraud agar medium (cultivated at 30°C for 3 days, used for the cultivation of Candida albicans); improved Sabouraud's agar medium (30°C, 3 days for cultivation of Microsporum furfur): glucose nutrient solution (37°C, 48h for anaerobic cultivation, for cultivation of Pr...
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