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Chinese herbal preparation for protecting diabetic heart injury and sports training method

A technology for heart injury and traditional Chinese medicine preparations, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, antidote, etc. It can solve problems such as the specific mechanism is not yet clear, and achieve the enhancement of SOD and GSH levels, low body drug resistance, Wide application prospects

Inactive Publication Date: 2019-03-19
PINGDINGSHAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Diabetic Cardiomyopathy (DC) is caused by diabetes mellitus, which is based on metabolic disorder and microvascular lesions and causes extensive necrosis of the myocardium. Serious clinical symptoms such as arrhythmia, heart failure and cardiogenic shock may occur, and it is fatal to patients. One of the main reasons, and currently there is no effective clinical method to prevent the occurrence of DC. The occurrence of DC is the result of multi-step and multi-factor participation. is one of the important common mechanisms

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The present invention proposes a traditional Chinese medicine preparation for protecting diabetic heart damage, comprising the following raw materials in parts by weight: 10 parts of astragalus, 15 parts of Chinese yam, 4 parts of ginseng, 3 parts of scrophulariaceae, 5 parts of Anemarrhena anemarrhena, 5 parts of corn silk, medlar 10 parts, Agrimony 15 parts, Purslane 5 parts, Digu bark 4 parts, Peanut rhizome 3 parts, Lychee core 4 parts, Silkworm cocoon shell 5 parts, Pomegranate peel 5 parts;

[0024] Its exercise training method includes the following steps:

[0025] S1: Select 65 male healthy adult SD rats, 6 weeks old, weighing 200±10g, pre-feed the rats with basal diet for 1 week, randomly select 10 rats by lottery as the normal group, and feed them with common diet, and the remaining 55 rats , given high-fat feed (common feed 66.5%, white sugar 20%, lard 10%, cholesterol 2.5%, sodium cholate 1%) for 4 weeks, fasting for 12 hours;

[0026] S2: One-time intraper...

Embodiment 2

[0031] The invention proposes a traditional Chinese medicine preparation for protecting diabetic heart damage, comprising the following raw materials in parts by weight: 11 parts of astragalus, 16 parts of yam, 5 parts of ginseng, 4 parts of crocodile, 6 parts of Anemarrhena, 6 parts of corn silk, wolfberry 11 parts, Agrimony 16 parts, Purslane 6 parts, Digu bark 5 parts, Peanut rhizome 4 parts, Lychee core 5 parts, Silkworm cocoon shell 6 parts, Pomegranate peel 6 parts;

[0032] Its exercise training method includes the following steps:

[0033] S1: Select 65 male healthy adult SD rats, 6 weeks old, weighing 200±10g, pre-feed the rats with basal diet for 1 week, randomly select 10 rats by lottery as the normal group, and feed them with common diet, and the remaining 55 rats , given high-fat feed (common feed 66.5%, white sugar 20%, lard 10%, cholesterol 2.5%, sodium cholate 1%) for 4 weeks, fasting for 12 hours;

[0034] S2: One-time intraperitoneal injection of STZ strepto...

Embodiment 3

[0039] The invention provides a traditional Chinese medicine preparation for protecting diabetic heart damage, comprising the following raw materials in parts by weight: 12 parts of astragalus, 17 parts of Chinese yam, 6 parts of ginseng, 5 parts of scrophulariaceae, 7 parts of anemarrhena, 7 parts of corn silk, medlar 12 parts, Agrimony 17 parts, Purslane 7 parts, Digu bark 6 parts, Peanut rhizome 5 parts, Lychee core 6 parts, Silkworm cocoon shell 7 parts, Pomegranate peel 7 parts;

[0040] Its exercise training method includes the following steps:

[0041] S1: Select 65 male healthy adult SD rats, 6 weeks old, weighing 200±10g, pre-feed the rats with basal diet for 1 week, randomly select 10 rats by lottery as the normal group, and feed them with common diet, and the remaining 55 rats , given high-fat feed (common feed 66.5%, white sugar 20%, lard 10%, cholesterol 2.5%, sodium cholate 1%) for 4 weeks, fasting for 12 hours;

[0042] S2: One-time intraperitoneal injection of...

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Abstract

The invention discloses a Chinese herbal preparation for protecting diabetic heart injury and a sports training method, wherein the Chinese herbal preparation for protecting diabetic heart injury contains the following materials in parts by weight: 10-14 parts of astragalus membranaceus, 15-19 parts of Chinese yam, 4-8 parts of ginseng, 3-7 parts of radix scrophulariae, 5-9 parts of rhizoma anemarrhenae, 5-9 parts of corn stigma, 10-14 parts of fruits of Chinese wolfberry, 15-19 parts of herba Agrimoniae, 5-9 parts of herba portulacae, 4-8 parts of cortex lycii radicis, 3-7 parts of peanut rhizome, 4-8 parts of lychee seeds, 5-9 parts of silkworm cocoon shell, and 5-9 parts of pericarpium granati. Extractive of the invention has a certain treatment effect for heart injury caused by diabetics, and whether the aim of collaborative treatment can be achieved by the combined application of aerobic exercise and Chinese herbal compound is discussed by experiments.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation and an exercise training method for protecting diabetic heart damage. Background technique [0002] Diabetes (DM) is a group of metabolic disorders characterized by elevated blood glucose levels caused by defects in the secretion or action of insulin in the body. Worldwide, there are about 230 million diabetic patients, and it is expected to reach 350 million by 2025. The incidence of diabetes in my country is also on the rise year by year. Diabetic Cardiomyopathy (DC) is the extensive necrosis of the myocardium caused by diabetes based on metabolic disorders and microvascular lesions, which can lead to severe clinical symptoms such as arrhythmia, heart failure, and cardiogenic shock, which can lead to the death of patients. One of the main reasons, and currently there is no effective method to prevent and preven...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P3/10A61P9/10A61P9/06A61P9/04A61P9/02A61P39/06A01K67/02A61K35/64
CPCA01K67/02A61K35/64A61K36/185A61K36/258A61K36/48A61K36/481A61K36/73A61K36/77A61K36/808A61K36/815A61K36/8945A61K36/8964A61K36/899A61P3/10A61P9/02A61P9/04A61P9/06A61P9/10A61P39/06A61K2300/00
Inventor 王瑜白现广于瑞雪吴茜胡思博
Owner PINGDINGSHAN UNIVERSITY
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