Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Quality detection method and application of traditional Chinese medicine composition for tonifying kidney and relaxing spine

A quality inspection method and composition technology, which is applied in the direction of drug combination, medical formula, medical preparations with non-active ingredients, etc., can solve the problems of traditional Chinese medicine with various flavors, mutual interference, and complex ingredients

Active Publication Date: 2019-05-21
BEIJING ZHONGYAN TONGRENTANG CHINESE MEDICINE R & D
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Therefore, the technical problem to be solved by the present invention is to provide a quality detection method and its application of a traditional Chinese medicine composition for invigorating the kidney and relaxing the spine, which overcomes the inability to comprehensively and clearly identify the traditional Chinese medicine due to its various flavors, complex components and mutual interference. The quality of the traditional Chinese medicine composition is detected and monitored, and the stability, consistency and controllability of the quality of the traditional Chinese medicine composition are improved

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Quality detection method and application of traditional Chinese medicine composition for tonifying kidney and relaxing spine
  • Quality detection method and application of traditional Chinese medicine composition for tonifying kidney and relaxing spine
  • Quality detection method and application of traditional Chinese medicine composition for tonifying kidney and relaxing spine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] Embodiment 1 Granules

[0071] Prescription: Rhizoma Drynariae 10g, Gouji 6g, Eucommia 6g, Guizhi 6g, Antler 4g, Corydalis Corydalis 7g, Dipsacus 7g, Gentiana chinensis 7g, Qingfengteng 9g and Notopterygium 6g;

[0072] Preparation method: Weigh Drynaria fortunei, Gouji, Eucommia, Guizhi, Antler, Corydalis Corydalis, Dipsacus, Gentiana chinensis, Qingfengteng and Qianghuo according to the selected parts by weight, and set aside; take Guizhi and Qianghuo two flavors, add 10 times Measure the water, steam distill for 6 hours, extract the volatile oil, collect the volatile oil, filter the water extract, and set aside; according to the volatile oil, β-cyclodextrin and water as 1ml: 6g: 60ml, add β-cyclodextrin and water to the volatile oil , stirred, clathrated for 30 minutes, refrigerated for 24 hours, filtered with suction, dried at 40°C to obtain clathrates of volatile oil, and set aside; take dog ridge, Eucommia ulmoides, antlers, and Dipsacus four flavors, add water an...

Embodiment 2

[0079] Embodiment 2 Granules

[0080] Prescription: Rhizoma Drynariae 8g, Dogji 4g, Eucommia 4g, Guizhi 4g, Antler 2g, Corydalis Corydalis 5g, Dipsacus 5g, Gentiana chinensis 5g, Qingfengteng 7g and Notopterygium 4g;

[0081] Preparation method: Weigh Drynaria fortunei, Gouji, Eucommia ulmoides, Guizhi, antlers, Corydalis Corydalis, Dipsacus, Gentiana chinensis, Qingfengteng and Qianghuo according to the selected parts by weight, and set aside; take Guizhi and Qianghuo, add 12 times Measure the water, steam distill for 4 hours, extract the volatile oil, collect the volatile oil, filter the water extract, and set aside; according to the volatile oil, β-cyclodextrin and water as 1ml: 4g: 80ml, add β-cyclodextrin and water to the volatile oil , inclusion compound for 60 minutes, refrigerated for 12 hours, suction filtered, dried at 50°C to obtain volatile oil inclusion compound, and set aside; take dog spine, Eucommia, antler, and Dipsacus four flavors, add water to decoct once, ...

Embodiment 3

[0088] Embodiment 3 granules

[0089] Composition: Rhizoma Drynariae 12g, Dogji 8g, Eucommia 8g, Guizhi 8g, Antler 6g, Corydalis Corydalis 9g, Dipsacus 9g, Gentiana 9g, Qingfengteng 11g and Notopterygium 8g;

[0090] Preparation method: Weigh Drynaria fortunei, Gouji, Eucommia, Guizhi, Antler, Corydalis Corydalis, Dipsacus, Gentiana chinensis, Qingfengteng and Qianghuo according to the selected parts by weight, and set aside; take Guizhi and Qianghuo, add 8 times Measure water, steam distill for 8 hours, extract volatile oil, collect volatile oil, filter the water extract, and set aside; according to the ratio of volatile oil, β-cyclodextrin and water: 1ml: 10g: 40ml, add β-cyclodextrin and water to the volatile oil , inclusion compound for 20 minutes, refrigerated for 48 hours, suction filtered, and dried at 30°C to obtain a volatile oil inclusion compound, which is then used for later use; take dog ridge, Eucommia ulmoides, antlers, and Dipsacus four flavors, add water to de...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
separationaaaaaaaaaa
separationaaaaaaaaaa
separationaaaaaaaaaa
Login to View More

Abstract

The invention provides a detection method of a traditional Chinese medicine composition. The traditional Chinese medicine composition comprises, by weight, the following medicinal raw materials: 8-12parts of drynaria rhizome, 4-8 parts of rhizoma cibotii, 4-8 parts of eucommia bark, 4-8 parts of cassia twigs, 2-6 parts of antlers, 5-9 parts of corydalis tuber, 5-9 parts of teasel roots, 5-9 partsof large-leaved gentian, 7-11 parts of caulis sinomenii and 4-8 parts of notopterygium roots. An appropriate extraction method or purification method is determined by screening for a limited number of times to prepare a test solution, appropriate chromatographic conditions are selected by utilizing an HPLC method, effective components in the traditional Chinese medicine composition are effectively separated from other impurities, and the contents of the effective components naringin and sinomenine in the traditional Chinese medicine composition are accurately determined; by using a TLC methodand adopting a proper developing agent, the identification of the corydalis tuber, large-leaved gentian and notopterygium roots in the traditional Chinese medicine composition is achieved. The methodis accurate, high in sensitivity, wide in detection range and capable of achieving effective control of medicine quality.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a quality detection method and application of a traditional Chinese medicine composition for invigorating the kidney and relaxing spine. Background technique [0002] Ankylosing spondylitis (AS) is a chronic progressive immune inflammatory disease of unknown cause, which mainly invades axial joints such as sacroiliac joints, spinal condyles, paraspinal soft tissues and peripheral joints, and may be accompanied by external performance. The main clinical manifestations are lumbosacral, back, neck, buttock, hip pain and joint swelling and pain. In severe cases, spinal deformity and joint stiffness may occur, affecting the patient's physical and mental health, and affecting the eyes, heart, lungs, kidneys and other organs. High disability rate. [0003] The treatment principle of the domestic guideline believes that there is no radical cure for ankylosing sp...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/66A61K47/69A61P19/00A61P19/02A61P29/00A61P37/02G01N30/02G01N30/06G01N30/90A61K35/32
Inventor 解素花段瑞刚杜菁张蓓
Owner BEIJING ZHONGYAN TONGRENTANG CHINESE MEDICINE R & D
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com