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Automatic screening device for clone cells

An automatic screening and cell technology, applied in biochemical cleaning devices, enzymology/microbiology devices, biochemical instruments, etc., can solve the problems of low labor efficiency, time-consuming and energy-consuming

Pending Publication Date: 2019-05-31
GUANGZHOU LABSIM BIOTECH CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the traditional method is to detect through complex ELISA experiments, or through limited dilution and manual cell sorting, which often takes a lot of time and energy, and the labor efficiency is low, and the results may not be satisfactory.

Method used

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  • Automatic screening device for clone cells
  • Automatic screening device for clone cells
  • Automatic screening device for clone cells

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Experimental program
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Embodiment Construction

[0047] Below will combine embodiment and Figure 1 to Figure 31The conception, specific structure and technical effects of the present invention are clearly and completely described so as to fully understand the purpose, features and effects of the present invention. Apparently, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, other embodiments obtained by those skilled in the art without creative efforts belong to The protection scope of the present invention. In addition, all the connection / connection relationships mentioned in this article do not refer to the direct connection of components, but mean that a better connection structure can be formed by adding or reducing connection accessories according to specific implementation conditions.

[0048] refer to figure 1 and figure 2 , an automatic screening device for clonal cells, comprising a rack 801 with a worktable,...

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Abstract

The invention discloses an automatic screening device for cloned cells, and relates to the technical field of biopharmaceutical instruments. The device comprises a rack with a workbench surface, and the rack is provided with a source microplate stack cover opening and closing module, a final microplate stack cover opening and closing module, a micro imaging module, a gun head stack module and an extraction injection movement module. A bin take-out and put-in mechanism in the source microplate stack cover opening and closing module drags corresponding culture dishes out, a carrying platform ofthe micro imaging module receives the culture dishes and conducts imaging analysis through a fluorescence microscope to determine the coordinates of a bacterial colony with the highest yield, the high-yield clonal cells are extracted by an injection pump of an extraction injection movement module and then moved and injected into the corresponding culture dishes of the source microplate stack coveropening and closing module, the bin take-out and put-in mechanism of the source microplate stack cover opening and closing module pushes the culture dishes into a storage bin, and full-automatic screening of the cloned cells is completed.

Description

technical field [0001] The invention relates to the technical field of biopharmaceutical equipment, in particular to an automatic screening device for cloned cells. Background technique [0002] Cell lines are not only a research tool for drug screening and experimental design, but also a carrier for biopharmaceutical development and large-scale production. Finding and selecting suitable cell lines is the key to successful drug research and production. For biopharmaceutical developers Said that the most dreaming thing is to screen a high expression cell line. However, the traditional method is to detect through complex ELISA experiments, or through limited dilution and manual cell sorting, which often takes a lot of time and energy, and the labor efficiency is low, and the results may not be satisfactory. Therefore, developing a set of screening equipment for cell cloning can provide strong support for the screening of cell cloning, greatly improve the efficiency of cell sc...

Claims

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Application Information

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IPC IPC(8): C12M1/00C12M1/22
Inventor 王治才许春华李其昌季舒瑶付文博
Owner GUANGZHOU LABSIM BIOTECH CO LTD