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Pharmaceutical composition used for treating allergic rhinitis and preparation method and application of pharmaceutical composition

A technology for allergic rhinitis and composition, which is applied in the field of pharmaceutical composition for treating allergic rhinitis and its preparation and application, and can solve problems such as unclear effect, no clinical experiment and effect data, complex formula, etc. Achieve the effect of broad market application prospects

Pending Publication Date: 2019-06-21
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Its formula is complicated, it is a decoction oral preparation, and the specific clinical experiment and effect data are not given in the article, so the effect is not clear

Method used

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  • Pharmaceutical composition used for treating allergic rhinitis and preparation method and application of pharmaceutical composition
  • Pharmaceutical composition used for treating allergic rhinitis and preparation method and application of pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0026] 1 Prescription: Sunburned Astragalus 30g, Atractylodes macrocephala 15g, Fangfeng 10g, Danpi 15g, Chuanxiong 10g

[0027] 2 preparation method:

[0028] 1) Distillation

[0029] Add 10 times the amount of water for Atractylodes macrocephala, Fangfeng, Cortex Moutan, and Rhizoma Chuanxiong, distill and extract for 5 hours, collect the aromatic water, and then redistill to collect 300ml of aromatic water, add 2ml of polysorbate 80, mix well, and set aside. The liquid medicine is collected in another device for use.

[0030] 2) decoction

[0031] Add 10 times the amount of water to the dregs obtained in step 1) and Astragalus membranaceus, decoct three times for 1 hour each time, filter, combine the decoction and the medicinal liquid obtained in step 1), and concentrate to a concentrated solution with a relative density of 1.05 (60°C).

[0032] 3) centrifugation, elution

[0...

Embodiment 2

[0037] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0038] 1 Prescription: Sunburned Astragalus 20g, Atractylodes macrocephala 20g, Fangfeng 7g, Danpi 20g, Ligusticum chuanxiong 7g

[0039] 2 preparation method:

[0040] With embodiment 1.

Embodiment 3

[0041] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0042] 1 Prescription: Sunburned Astragalus 40g, Atractylodes macrocephala 10g, Fangfeng 13g, Danpi 10g, Chuanxiong 13g

[0043] 2 preparation method:

[0044] With embodiment 1.

[0045] The beneficial effects of the present invention will be described below by means of test examples.

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Abstract

The invention provides a pharmaceutical composition used for treating allergic rhinitis and a preparation method and application of the pharmaceutical composition. The pharmaceutical composition comprises, by weight, 20-40 parts of astragalus membranaceus, 10-20 parts of rhizoma atractylodis macrocephalae, 7-13 parts of radix saposhnikoviae, 10-20 parts of cortex moutan and 7-13 parts of ligusticum wallichii. The test results show that compared with existing western medicine for allergic rhintis, the pharmaceutical composition has the advantages that the composition is safe and effective in improving symptoms of qi deficiency and blood stasis and long-term curative effect and wide in market application prospect.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating allergic rhinitis, a preparation method and application thereof. Background technique [0002] Allergic rhinitis is allergic rhinitis, which refers to the release of mediators (mainly histamine) mediated by IgE after atopic individuals are exposed to allergens, and a variety of immune active cells and cytokines are involved. Noninfectious inflammatory disease of the mucosa. Allergic rhinitis is a global health problem that can lead to many diseases and even loss of labor force. Its risk factors may exist in all age groups. In addition, the air pollution in China is becoming more and more serious, which makes the incidence of allergic rhinitis on the rise. . [0003] The main symptoms of allergic rhinitis are sneezing, runny nose, nasal congestion, and nasal itching, some of which are accompanied by hyposmia. This greatly endangers the patient's health, and may affect the patient's no...

Claims

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Application Information

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IPC IPC(8): A61K36/65A61K36/71A61P11/02A61P37/08
Inventor 田理刘宝刘莉
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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