A kind of aggregation-induced luminescent fluorescent material and its preparation method and application

A technology of aggregation-induced luminescence and fluorescent materials, applied in the application field of labeling lipid droplets, can solve the problems of fluorescence quenching and low solid quantum yield, and achieve good biocompatibility
CN109912634BInactive Publication Date: 2021-02-26SHAANXI NORMAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHAANXI NORMAL UNIV
Publication Date
2021-02-26
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a kind of aggregation-induced luminescent fluorescent material and its preparation method and application. 1 ~C 4 Alkyl, C 1 ~C 3 Alkoxyl, hydroxyl or N,N-dimethyl, which use salicylaldehyde derivatives and p-substituted aniline as raw materials, obtain intermediate imine through simple dehydration condensation reaction, and then react with boron trifluoride ether form. The fluorescent material of the invention has aggregation-induced luminescent properties, can specifically mark lipid droplets in living cells, and is a class of excellent lipid droplet imaging dyes.
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Description

technical field

[0001] The invention belongs to the technical field of fluorescent materials for biomedicine, and in particular relates to a fluorescent material with aggregation-induced luminescence properties, a preparation method of the fluorescent material and an application in marking lipid droplets. Background technique

[0002] Fluorescent materials have attracted great attention of scientists in recent years due to their great application value in optoelectronic devices, environmental sensors, biological sciences and other fields. Fluorescence detection not only has high sensitivity, but also overcomes a series of problems that require expensive and difficult-to-operate radioactive tracing reagents in biochemical experiments. Fluorescence imaging reveals the localization and measurement of molecules within cells, and sometimes enables detection at the single-molecule level. At present, there are many reports on biological imaging of lipid droplets, and the research ...

Claims

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