Real-time monitoring cell return liquid uniform shaking device

A real-time monitoring and cell technology, which is applied in the field of medical devices, can solve the problems of not overcoming the gravity of cells, cell sedimentation, inability of cells to be completely reinfused into patients, and vascular medical accidents, so as to avoid human negligence, solve cell clumping and adhesion, The effect of improving safety

Inactive Publication Date: 2019-06-28
GUANGZHOU UNIVERSITY
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AI-Extracted Technical Summary

Problems solved by technology

[0003] Cell reinfusion is an important part of cell therapy technology. At present, cell reinfusion bags are mostly used for cell reinfusion. However, due to the biological characteristics of cells, the cells in the reinfusion suspension tend to form agglomerates or stick to the inner wall of the cell reinfusion bag. At least, the cells in the cell reinfusion bag cannot be completely returned to the patient, resulting in waste of cells, and at worst, medical accidents due to blockage of blood vessels by cell clus...
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Method used

Riser is positioned at the leftmost position of frame. A protruding installation part is arranged on the upper part of the vertical plate of the frame, and the installation part is an inverted isosceles trapezoid. When in use, the outer position where the shaking device is placed is provided with a receiving groove compatible with the ...
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Abstract

The invention relates to a real-time monitoring cell return liquid uniform shaking device, and belongs to the field of medical instruments. The device comprises a placement box for fixedly accommodating a cell return bag, a shaking system, a monitoring control system and a rack; the shaking system comprises a motor and a crank and rocker mechanism; the crank and rocker mechanism comprises a crank,a rocker, a fixed supporting rod and a connecting rod; a transmission shaft of the crank is rotationally arranged on the rack and is fixedly connected with a rotating shaft of the motor, and the tailend of a rotating part of the crank is rotationally connected with the lower end of the connecting rod; the lower end of the fixed supporting rod is fixed to the rack; one end of the rocker is rotationally connected with the upper end of the fixed supporting rod, and the other end of the rocker is rotationally connected with the upper end of the connecting rod; the placement box is fixed to the rocker; the monitoring control system monitors the state of the cell return bag, and controls the shaking system to be started or stopped. Cell return liquid can be efficiently and automatically shakenuniformly, the shaking action is stopped after uniform shaking, manpower is saved, manual work negligence is avoided, and the cell return safety is improved.

Application Domain

Shaking/oscillating/vibrating mixersMixer accessories

Technology Topic

Control systemIndustrial engineering +2

Image

  • Real-time monitoring cell return liquid uniform shaking device
  • Real-time monitoring cell return liquid uniform shaking device
  • Real-time monitoring cell return liquid uniform shaking device

Examples

  • Experimental program(1)

Example Embodiment

[0023] The present invention will be further described in detail below in conjunction with specific embodiments.
[0024] A real-time monitoring cell reinfusion shaking device includes a placing box for fixedly placing a cell reinfusion bag, a shaking system, a monitoring control system, and a rack.
[0025] The frame includes a vertical plate, side plates fixed at the front and rear ends of the vertical plate, and a control box behind the rear end side plate; the control box is fixedly connected to the rear end of the vertical plate; the side plate is provided with a shaft hole.
[0026] The riser is located at the leftmost position of the rack. The upper part of the vertical plate of the frame is provided with a protruding installation part, and the installation part is inverted isosceles trapezoid. When in use, the external position where the shaking device is placed is provided with a receiving groove adapted to the installation part; the receiving groove supports the installation part upwards to support the entire shaking device. A fixed strong magnet is fixed on the vertical plate, and the external position of the shaking device when in use is connected with the vertical plate of the frame through magnet adsorption to make the device more stable.
[0027] The rocking system includes a motor and a crank rocker mechanism.
[0028] The motor is a geared motor. The motor is fixed on the right side of the control box. The control components of the monitoring and control system are arranged in the control box, and the control box is provided with a switch.
[0029] The crank-rocker mechanism includes a crank, a rocker, a fixed support rod, and a connecting rod.
[0030] The crank includes a transmission shaft and a rotating part, and the rotating part is perpendicular to the transmission shaft and fixedly connected. The transmission shaft of the crank passes through and is installed in the shaft hole of the front side plate of the frame vertical plate through the bearing, and the motor shaft passes through and is installed in the shaft hole of the rear side plate of the frame vertical plate through the bearing rotation; The rotating shaft of the motor and the rotating shaft of the crank are connected together by an elastic coupling between the front and rear side plates.
[0031] The tail end of the rotating part of the crank is rotatably connected with the lower end of the connecting rod; the lower end of the fixed support rod is fixed on the upper end of the frame vertical plate, and the upper end faces the upper right; one end of the rocker is rotatably connected with the upper end of the fixed support rod, and the other end is connected with The upper end of the connecting rod is rotated and connected.
[0032] The placing box is fixed on the rocker and is level with the rocker; the placing box is a square frame box, and the cell return bag state can be seen when the cell return bag is placed in the box.
[0033] The placing box includes an upper box body and a lower box body stacked up and down; in the side of the placing box close to the rocker, the upper box body and the lower box body are rotatably connected together by a connecting pin; on at least one side of the remaining side Wherein, the upper box body is provided with an upper attracting magnet, and the lower box body is provided with a lower attracting magnet; the upper attracting magnet and the lower attracting magnet are attracted and attached to close the upper box body and the lower box body.
[0034] An elastic band is arranged in a plane on the lower side of the upper box body, and an elastic band is arranged in a plane on the upper side of the lower box; the elastic band is tensioned and distributed on the plane by fixing screws. When in use, the cell return bag is placed between the upper and lower elastic bands along the length of the rocker, and the elastic bag tightens and fixes the cell return bag; the opening of the cell return bag is located at the end close to the fixed support rod.
[0035] When shaking, the crank rotates within 360°, driving the rocker to swing within 90°; the pivot point of the rocker is the position where the rocker connects with the upper end of the fixed support rod; when the crank rotates to the lowest position, the rocker is relative to the horizontal The position is tilted down by 45 degrees; when the crank rotates to the highest position, the rocker tilts up by 45 degrees relative to the horizontal position.
[0036] The monitoring and control system monitors the status of the cell return bag and controls the start or stop of the shaking system.
[0037] The monitoring and control system includes a concentration sensor, which judges the concentration by collecting the transmitted light intensity. The concentration sensor includes a transmitting array bar and a receiving array bar; the transmitting array bar is evenly distributed with transmitting points, that is, the transmitting array, and the receiving array bar is evenly distributed with receiving points corresponding to the transmitting points, that is, the receiving array; the transmitting array bar The receiving array and the receiving array are arranged along the length direction of the rocker, and are respectively fixed on the upper elastic belt and the lower elastic belt, wherein the transmitting array and the receiving array are arranged symmetrically about the plane. In the transmitting array and the receiving array, there are a pair of transmitting points and receiving points located on the upper and lower sides of the opening of the cell reinfusion bag; a pair of transmitting points and receiving points located on the upper and lower sides of the opening of the cell reinfusion bag are used to monitor the cell reinfusion bag. The amount of liquid, when the cell back-infusion injection is completed, the alarm system is triggered to inform relevant personnel that the infusion has been completed.
[0038] The monitoring and control system includes a Hall sensor, which is set on the front side plate of the frame opposite to the crank that rotates to the highest position; when it needs to stop after shaking, the Hall sensor monitors when the crank rotates to the highest position. The control system controls the shaking system to stop.
[0039] Among them, the cell reinfusion bag is a standable bag.
[0040] When in use, it is fixedly placed in the external receiving groove by the vertical plate; during the cell reinfusion, the concentration sensor monitors the concentration of the cells in different positions of the infusion in real time. When the concentration difference exceeds the threshold, the motor starts to perform the shaking operation. After shaking, stop; among them, when the shaking operation is stopped, the position of the crank is monitored by the Hall sensor. When the crank rotates to its highest position, that is, the opening of the cell reinfusion bag faces downward and the inclination of the cell reinfusion bag is the largest When, stop the motor. The concentration sensor located on the open side of the cell reinfusion bag can also monitor whether the cell reinfusion has completed the reinfusion, and when the cell reinfusion is over, a voice prompt will be issued.
[0041] The above-mentioned embodiments are preferred embodiments of the present invention, but the embodiments of the present invention are not limited by the above-mentioned embodiments, and any other changes, modifications, substitutions, combinations, etc. made without departing from the spirit and principle of the present invention Simplified, all should be equivalent replacement methods, and they are all included in the protection scope of the present invention.

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