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Discriminating model for Crohn's disease and intestinal Behcet disease, and model constructing method

A Crohn's disease and identification model technology, which is applied in the field of disease differentiation and identification models, achieves the effects of strong operability and high prediction accuracy

Pending Publication Date: 2019-07-09
PEKING UNION MEDICAL COLLEGE HOSPITAL CHINESE ACAD OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In order to overcome the problems of not being able to select effective and appropriate indicators for the identification of Crohn's disease and Behçet and how to assign values ​​to each indicator effectively, the present invention provides a identification model and model construction method for Crohn's disease and Behcet

Method used

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  • Discriminating model for Crohn's disease and intestinal Behcet disease, and model constructing method
  • Discriminating model for Crohn's disease and intestinal Behcet disease, and model constructing method
  • Discriminating model for Crohn's disease and intestinal Behcet disease, and model constructing method

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Effect test

Embodiment 1

[0051] Example 1 A method for constructing a differential model for Crohn's disease and intestinal Behçet

[0052] Firstly, from January 1, 2004 to December 30, 2018 in Peking Union Medical College Hospital, the First Affiliated Hospital of Sun Yat-sen University, the Sixth Affiliated Hospital of Sun Yat-sen University, Shanghai Renji Hospital, Shanghai Tenth Hospital, Xijing Hospital and Run Run Shaw Patients with Crohn's disease and Behçet entero-behcet who have been continuously diagnosed and treated by multiple centers in the hospital with complete clinical, endoscopic and imaging data, including 113 cases of Crohn's disease and 70 cases of entero-Behcet.

[0053] 1. Diagnostic criteria:

[0054] The diagnosis of Crohn's disease is based on the ECCO guidelines and China's "2012 Consensus on the Diagnosis and Treatment of Inflammatory Bowel Diseases": on the basis of excluding other diseases, the diagnosis can be made according to the following points: (1) Diarrhea, abdomin...

Embodiment 2

[0095] Embodiment 2 A kind of identification instrument of Crohn's disease and intestinal Behcet

[0096] A device for identifying Crohn's disease and intestinal Behcet, which includes a rectangular structure 1, the upper part of the rectangular structure 1 is a table partition structure, and the upper part of the table partition includes an "indicator" grid 2 and a "yes score" grid 3;" "no score" box 4; the bottommost box is the specific indicator name box, and the score box behind the same row; respectively, the score boxes corresponding to whether each indicator is yes or no; the bottom line is the total row 5, and the total score is counted; the specific indicator box They are: "genital ulcer" grid 61, "skin lesions" grid 62, "circular ulcer" grid 63, "longitudinal ulcer" grid 64, "total number of ulcers > 5" grid 65, "inflammatory polyps" Box 66, "Severe enhancement of the mucosal surface" Box 67, "Increased fat density around the mesentery" Box 68.

[0097] Set up a cla...

Embodiment 3

[0111] Embodiment 3 A kind of identification model and model construction method of Crohn's disease and intestinal Behcet

[0112] A device for identifying Crohn's disease and intestinal Behcet, which includes a rectangular structure 1, the upper part of the rectangular structure 1 is a table partition structure, and the upper part of the table partition includes an "indicator" grid 2 and a "yes score" grid 3;" "no score" box 4; the bottommost box is the specific indicator name box, and the score box behind the same row; respectively, the score boxes corresponding to whether each indicator is yes or no; the bottom line is the total row 5, and the total score is counted; the specific indicator box They are: "genital ulcer" grid 61, "skin lesions" grid 62, "circular ulcer" grid 63, "longitudinal ulcer" grid 64, "total number of ulcers > 5" grid 65, "inflammatory polyps" Box 66, "Severe enhancement of the mucosal surface" Box 67, "Increased fat density around the mesentery" Box 6...

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Abstract

A discriminating model for a Crohn's disease and an intestinal Behcet disease comprises scores of corresponding indexes in at least two aspects of clinical representation, an endoscope characteristicand an imaging characteristic and the summation of scores of the corresponding indexes. The indexes of the clinical representation comprise genitals ulcer and skin lesion; wherein the indexes of the endoscope characteristic comprise quasi-circular ulcer and longitudinal ulcer; the total number of ulcers is higher than 5; inflammatory polyp; wherein the indexes of the imaging characteristic comprise severe enhancement of a mucosal surface and fat density increase around a mesentery; wherein the Crohn's disease is diagnosed when the total number is higher than 1, and the intestinal Behcet disease is diagnosed when the total number is lower than or equal with 1. Through the model of the invention, discriminating of the Crohn's disease and the intestinal Behcet disease can be effectively realized. The discriminating model has advantages of simple operation, high speed and high accuracy. Furthermore the invention discloses a constructing method and a verifying method of the model, thereby ensuring high effectiveness of the model. Furthermore the invention designs a corresponding discriminating tool for more visually and quickly understanding a disease condition.

Description

technical field [0001] The invention belongs to the technical field of disease differentiation and identification models, especially for the convenience of identification of Crohn's disease and intestinal Behcet, and specifically relates to a identification model of Crohn's disease and intestinal Behcet and a method for constructing the model. Background technique [0002] Crohn's disease is an inflammatory bowel disease of unknown cause that can occur anywhere in the gastrointestinal tract. The disease and chronic ulcerative colitis are collectively referred to as inflammatory bowel disease. The clinical manifestations of this disease are abdominal pain, diarrhea, and intestinal obstruction, accompanied by extraintestinal manifestations such as fever and nutritional disorders. Intestinal Behcet's disease was first proposed by Turkish dermatologists in 1937. It is a systemic, chronic, vascular inflammatory disease. The main clinical manifestations are recurrent oral ulcers,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/70G16H50/50G16H50/30G16H40/63G16H10/00G06C3/00B43L1/00
CPCB43L1/00G06C3/00G16H10/00G16H40/63G16H50/30G16H50/50G16H50/70
Inventor 钱家鸣张慧敏杨红韩伟谭蓓郭涛赖雅敏刘炜周炜洵李骥陈旻湖高翔冉志华刘占举吴开春曹倩
Owner PEKING UNION MEDICAL COLLEGE HOSPITAL CHINESE ACAD OF MEDICAL SCI
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