52 results about "Mesenteries" patented technology

A stent graft includes a pair of generally opposed windows alignable with the superior mesentery artery, the celiac trunk and separated by graft material. A stent is provided spanning the window and in contact with the adjacent graft material and the stent presses the adjacent graft material into engagement with the adjacent wall of the flow lumen. A branch graft connection into the renal arteries may also be provided.

The equipment for monitoring micro circulation body flow time-space response characteristic on mesentery includes an optical path and an imaging system. In the optial path, the laser bean from helium neon laser is coupled to fiber bundle to form homogeneous diffused beam; and the imaging system consists of stereo microscope with CCD camera, image collecting card with image collecting and controlling software. The CCD signal is output to the image collecting card connected to PC, the collection parameters are set via the image collecting and controlling software and local blood flow information are obtained with the image signal and via the signal analysis software. The equipment provides one new way to the research of influence of medicine and other stimulation to the micro circulation blood flow on mesentery.

Devices and systems have a sensor probe configured to measure tissue oxygen saturation in the intestine or mesentery. The devices and systems can determine the oxygenation state of the entire thickness of the intestine or mesentery. Thus, embodiments of the invention can be applied in diagnosing intestinal ischemia in a patient, as well as in monitoring tissue oxygen saturation of the intestine or mesentery during or after a surgical procedure.

The invention relates to the pharmacy field of traditional Chinese medicines, in particular to application of total flavonoid in astragalus to preparing medicaments for preventing and controlling diabetes and nephropathy. The invention investigates the influence of the total flavonoid in astragalus on the cell proliferation and the cell extracellular matrix hyperplasia of a glomerulus mesentery of a rat as well as the therapeutic effect of the total flavonoid in astragalus on a mouse with the diabetes and the nephropathy; and the experimental result proves that the total flavonoid in astragalus has remarkable treating and preventing functions on the diabetes and the nephropathy, thus the invention provides application of total flavonoid in astragalus to preparing medicaments for preventing and controlling diabetes and nephropathy and a medicinal composition which contains the total flavonoid in astragalus and is used for preventing and controlling the diabetes and the nephropathy, and thereby providing a new medicine choice for treating and preventing the diabetes and the nephropathy.

The invention relates to separation, purification and primary culture methods of intestinal macrophages in Ctenopharyngodon idella. The separation method comprises: taking out the rear middle segment of an intestine by aseptic operation, removing intestinal outer fat and mesentery, longitudinally cutting the intestine to clear excrement, and using aseptic bent-tip tweezers to scrape off the intestinal mucus and epithelial cell layer for 15 min; cutting the segment with the mucus and epithelial cell layer removed to obtain fragments, and digesting the fragments in collagenase IV digestive juice to obtain lamina propria single-cell suspension; using a separation kit of fish organ monocytes to separate the intestinal macrophages. The purification method comprises: using a differential wall attachment method to purify the intestinal macrophages. The primary culture method comprises: using RPMI (Roswell Park Memorial Institute medium) 1640 complete culture solution containing autoserum of Ctenopharyngodon idella to culture the intestinal macrophages, changing the solution once with lipopolysaccharide-containing RPMI 1640 complete culture solution after cells attach to the wall, and changing the solution once every other two days so that cells may survive for at least 20 days. The separation, purification and primary culture methods established herein have good operability and repeatability.

A preparing method of a small-intestine decellularized scaffold with a complete three-dimensional structure and a vascular network is disclosed. The method is characterized by comprising following steps: a first step of selecting a healthy adult mammal, anesthetizing, injecting with an anticoagulant, opening the abdominal cavity, subjecting the small intestine section to cannula fixation for artery and vein vessels, and ligating at the proximal end to break the vessels; a second step of clipping two ends of the small intestine section, breaking the two ends of the small intestine section, respectively performing cannula fixation, separating a mesentery, taking down a complete intestinal tube and a complete mesenteric vessel which are needed, putting into a low-temperature environment, and repeatedly washing with normal saline; a third step of perfusing the artery, the vein and the intestinal tube with a phosphate buffer, a trypsin solution containing ethylenediaminetetraacetic acid, the phosphate buffer, a sodium dodecylsulfate solution, the phosphate buffer, a polyethylene glycol octylphenol ether solution and the phosphate buffer in order; and a fourth step of disinfecting after perfusion. The small-intestine decellularized scaffold prepared by the method can maintain a complete scaffold structure.

The invention discloses application of 3,4-dihydroxyl-phenyl lactic acid in preparing a medicine treating microcirculatory disturbance. Salvia Miltrorrhiza (SM) is contained in a great number of the prior Chinese medicines used to treat blood vessel diseases, and 3,4-dihydroxyl-phenyl lactic acid(DLA) is one of main active ingredients in the Salvia Miltrorrhiza. The microcirculatory disturbance is mesentery microcirculatory disturbance and is caused by ischemia/reperfusion. The invention also discloses application of the 3,4-dihydroxyl-phenyl lactic acid in preparing a medicine for preventing adhesion of white blood cells caused by the microcirculatory disturbance, a medicine for restoring adhesional white blood cells caused by the microcirculatory disturbance, a medicine for inhibiting exudation of albumin from small veins caused by the microcirculatory disturbance, a medicine for inhibiting degranulation of mast cells caused by the microcirculatory disturbance, a medicine for inhibiting expressions of adersional molecules CD11b and CD18 on neutrophilic granulocytes caused by the microcirculatory disturbance and a medicine for inhibiting generation of peroxides caused by the microcirculatory disturbance.

The invention belongs to the field of biological suture lines and particularly relates to a novel catgut degreasing technological method. The novel catgut degreasing technological method includes the following steps of 1, cleaning, wherein a fresh sheep intestine and a cattle casing are selected, blood-containing water on the surface of the casing is washed away with clean water, and then mucosa, serosa and mesentery in the casing are removed; 2, freezing, wherein the cleaned casing is placed in a refrigeration house after surface water of the casing is removed, the temperature of the refrigeration house is below -60 DEG C, and the refrigeration time ranges from 20 h to 24 h; 3, freeze-drying, wherein freeze-drying is carried out for 48 hours at the temperature of -40 DEG C to -45 DEG C, the casing is wrapped by filter paper, and the casing is put in an extractor; 4, degreasing, wherein the freeze-dried casing is put in alkali liquor at the temperature of 18 DEG C to be treated for 8-12 h, and then a degreasing agent is added for treatment for 12 h. Degreasing efficiency is improved, the degreasing rate reaches 98%, no fat white dot exists on the appearance of a catgut body, and anti-tensile strength is enhanced by 20%.

The invention discloses a traditional Chinese medicine composition. The composition is prepared from, by weight, 200-205 parts of radix rehmanniae preparata, 130-140 parts of Chinese pyrola herbs, 130-140 parts of rhzizoma drynariae, 130-140 parts of suberect spatholobus stem, 130-140 parts of cistanche deserticola, 130-140 parts of epimedium herbs and 80-90 parts of fried radish seeds. The invention further discloses a preparation method and application of the traditional Chinese medicine composition. The composition has the functions of tonifying the kidney, activating blood, diminishing inflammation and relieving the pain. The traditional Chinese medicine composition is used for hypertrophic myelitis, cervical spondylosis, calcaneal spur, proliferative arthritis and Kashin-Beck diseases. The composition further has the functions of improving mesentery circulation and promoting functional repairing of the stomach and intestines and is applied to treatment of stomach and intestine injuries and the like.

The invention discloses an application of des-O-methyllasiodiplodin in preparation of a medicament for treating kidney diseases. Experimental studies show that the des-O-methyllasiodiplodin has a good effect of protecting the kidney, has an obvious inhibiting effect on pathological symptoms such as urinary protein sum rise, foot process fusion and disappearance, podocyte injury, glomerular nucleated cell sum rise, mesentery area and glomerular area enlargement, crescent formation and proliferating cell nuclear antigen (PCNA) and methyl cyclopentenolone 1 (MCP-1) expression, and has a good prevention and treatment effect on multiple kidney diseases. Obvious adverse response is avoided in the experimental process, and the des-O-methyllasiodiplodin is expected to be developed into a new-generation safe and effective medicament for treating the kidney diseases.

The invention discloses a medicament for treating phlegm and blood stasis coronary heart disease caused by atherosclerosis. The medicament is prepared from the following components by weight: 5-20 g of rhizoma pinellinae praeparata, 5-20 g of safflower, 5-20 g of dried old orange peel, 5-20 g of peach kernel, 5-20 g of red peony root, 6-24 g of indian buead, 5-20 g of dried rehmannia root, 6-24 gof Chinese angelica root, 2-6 g of rhizome of Sichuan lovage, 0.05-0.2 g of artificial moschus and 2.5-10 g of liquoric root. The medicament has the advantages of remarkably protecting myocardial ischemia, activating blood, resisting coagulation, remarkably prolonging the survival time of a mice under normal pressure and oxygen-poor condition, remarkably improving the microcirculation disturbance of mesenteries of the mice, relieving pain, enhancing the normal-pressure oxygen deficiency resistance of the mice and improving the microcirculation. The medicament has a good clinical heating effect on obstruction of meridian by blood stasis and phlegm caused by coronary heart disease and angina pectoris, and has high safety.

The invention discloses a traditional Chinese medicine formula for treating mesentery lymphadenitis of children. The formula consists of Chinese herbal medicines such as radix codonopsitis, rhizoma atractylodis alba, poria, dried orange peel, liquorice, forsythia suspense, fructus schizandrae, cortex lycii radicis and almond; if a child has a fever, bupleurum and kudzu root can be added in the formula; if the child has indigestion, charred triplet, corium stomachium galli and rhizoma picrorrhiza are added in the formula; and the materials are added with water and decocted into liquor or powder. The formula has the efficacies of tonifying qi, supporting the healthy energy, removing toxins and clearing away heat.

The invention relates to a method of comprehensive utilization and processing of puffer fish. Firstly, puffer fish is cleaned and treated to remove the blood, and then fish fins, the mouth, the skin, the eyes, the gill and the viscera are cut off, thereby implementing external treatment. Secondly, the head, the viscera, the body and the bone of the puffer fish are respectively treated, thereby implementing internal treatment. Further, the blood, the mucosa, the mucilage, the subcutaneous tissue, the fin, the eyes, the kidney, the heart, the gallbladder, the spleen, the stomach, the intestines, the mesentery, the bladder and the anus in the process are placed in a dish for inedible parts. Finally, the treated fins, skin, mouth, head, muscles, testicle and bones are placed in a dish for edible parts; and the ovary and the liver are placed in a dish for highly toxic parts. The method ensures the safety and sanitation of the puffer fish processed products to the greatest extent in methodology and process flow, ensures the safety and stability in the edibility of the puffer fish after long-term preservation, and realizes the comprehensive utilization of puffer fish resource.

The invention relates to a self-expanding trumpet flower protective umbrella device for aorta abdominalis, and belongs to the technical field of medical instruments. Comprising an outer sheath tube, an inner sheath tube and a protective umbrella, a hollow inner layer sheathing canal is arranged in the outer layer sheathing canal in a penetrating manner; a protective umbrella is arranged between the inner-layer sheathing canal and the outer-layer sheathing canal, the protective umbrella is in the shape of a cone with the bottom turned outwards, an umbrella tip of the conical protective umbrella is arranged on the side close to an operator, and the bottom of the protective umbrella is arranged on the side away from the operator; an outer net bag ring is arranged at the edge of the bottom of the protective umbrella; an artery wall anchoring part is arranged on the protective umbrella close to the outer side net bag ring, and an inner side net bag ring is arranged in the protective umbrella; the problem that the renal artery and the lower limb artery are embolized due to chippings falling caused by superior mesenteric artery thrombectomy operation can be solved, the arterial wall anchoring part at the head end of the trumpet-flower-shaped umbrella body can effectively grab the wall, and the problem that the protection umbrella is not firmly fixed due to flushing of blood flow in the artery is solved; the double-layer net bag ring can keep the plasticity of the net bag and prevent the protection umbrella from deforming.

The invention relates to a method for manufacturing an animal thrombosis model, in particular to an establishment method for a rat peripheral superior mesenteric vein thrombosis model. The model is established by establishing a strangulation type peripheral superior mesenteric vein thrombosis model, entering an abdomen from an incision, about 2 cm long, right in the center of the abdomen, taking out a small intestine at the position 20 cm away from an ileocecal junction, measuring the length of the inner side edge of the small intestine, the first-stage branch of a mesenteric vein and arciform veins on the two sides through a nylon suture, and blocking mesentery veins and arciform veins within the 6-centimeter area of the inner side edge of the small intestine. A pure peripheral superior mesenteric vein thrombosis model is established by entering the abdomen from the incision, about 2 cm long, right in the center of the abdomen, taking out the small intestine at the position 20 cm away from an ileocecal junction, measuring the length of the inner side edge of the small intestine, the first-stage branch of the mesenteric vein and the arciform veins on the two sides through a nylon suture, and blocking mesentery veins and arciform veins within the 3-centimeter area of the inner side edge of the small intestine. The rat peripheral superior mesenteric vein thrombosis model is suitable for superior mesenteric vein thrombosis intestinal pathology and pathophysiology research.

An appendectomy model comprises a cecum, a cecum inner wall, an appendix, a blood vessel, a mesentery 1, a mesentery 2 and an ileum. The appendectomy model simulates a real human anatomical tissue structure, wherein the positions of all tissue parts and the mutual connection are correct; the whole structure except the blood vessel is made of a silica gel material; the blood vessel is made of a rubber tube, and liquid can be connected into the blood vessel, and when the blood vessel is cut off, the liquid flows out; the mesentery is detachably connected with the cecum and the ileum; the appendix is fixedly connected with the mesentery; the appendix part can be replaced; and the appendectomy model can be used as a medical teaching aid, and can also be used as a training model of appendix resection and a training model of intestinal suture.

The invention discloses an animal mesenteric microcirculation observation system, which includes an experimental device and an observation device; the observation device includes a special microscope, and an observation position adjustment device is arranged on the base of the special microscope, and the observation position adjustment device is for the vertical column of the microscope along the horizontal plane. The structure is fine-tuned in two mutually perpendicular directions; the special microscope is a movable microscope, which realizes the separation of the special microscope and the experimental device. Using the above technical scheme, the animal mesenteric microcirculation observation system has ingenious and reasonable design, convenient operation, stable technology, and good microcirculation observation effect, which better solves the technical problem of simulating the intraperitoneal environment of the mesenteric microcirculation in vitro; The way to fix the observation object will not cause the observation object to be involved, making it more convenient to adjust the observation field of view and position, and the observation effect is better.

The invention discloses a drug for treatment of children mesentery acute lymphadenitis. The drug is prepared from the following components by weight: 8-12g of rhizoma cyperi, 8-12g of rhizoma chuanxiong, 8-12g of rhizoma atractylodis, 8-12g of aflatoxin, 8-12g of fructus gardenia, 8-12g of roasted rhizoma atractylodis macrocephalae and 8-12g of pleione bulbocodioides. According to the drug for treatment of the children mesentery acute lymphadenitis, an ancient formula is applied into a modern disease spectrum, and a novel Chinese medicine treatment drug for children mesentery lymphadenitis inthe acute stage is provided.

The invention discloses a method for collecting hepatic portal vein blood of cynomolgus monkeys, and relates to the technical field of blood collection. Comprising the following steps: preoperative preparation work; cutting up and down along the middle abdominal line of the animal by taking the navel as a base point; after the abdominal cavity is exposed, the jejunum section of the animal is slightly pulled out of the abdominal cavity; a vein on the mesentery of the jejunum section is separated, the telecentric end is ligated, the proximal end is clamped by a vein clamp, and then a silk thread penetrates through the vein; a small opening is cut in the distal end of the vein, a catheter is inserted, after the catheter is inserted into the vein by 0.8-1.2 cm, a silk thread placed in advance is knotted, and the vein clamp is removed; the catheter is continuously inserted by 7-8 cm, and whether the catheter reaches the hepatic portal vein or not is detected by going deep into the abdominal hepatic portal vein with the hand; the catheter is fixed; resetting the ileum, leading the catheter out of the abdominal cavity, and closing the abdominal cavity; a small opening is formed in the abdominal wall on the right side, and the catheter is connected with the Port and buried subcutaneously.