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8 results about "Laser Speckle Imaging" patented technology

A noninvasive, non-scanning optical imaging technique that provides full-field visualization of blood flow to the tissue being imaged, which provides information about tissue perfusion and the efficiency of disease treatment.

Gas leakage detection method and system based on laser speckle imaging

The invention discloses a gas leakage detection method and system based on laser speckle imaging, and the method comprises the steps: irradiating the outer wall surface of a to-be-monitored region with laser beam expansion to form laser speckles, and continuously collecting a plurality of monitoring speckle images of the to-be-monitored region; segmenting the monitored speckle image and the corresponding original speckle image without leakage into a plurality of sub-windows, and calculating the frequency spectrum amplitude and the frequency spectrum phase of each sub-window; calculating a correlation coefficient between the two sub-windows according to the spectrum amplitudes and the spectrum phases of the sub-windows corresponding to the original speckle image and the monitoring speckle image; marking the sub-windows in the monitoring speckle image corresponding to all the correlation coefficients smaller than a preset threshold value as gas leakage coarse positioning areas; and for each pixel point in the leakage coarse positioning area, calculating a pixel-level imaging operator of the pixel point, and taking the pixel point corresponding to the maximum pixel-level imaging operator as a gas leakage point.
Owner:SOUTHWEST JIAOTONG UNIV

Mechanical perfusion heart coronary artery recognition and flow velocity estimation method based on laser speckle imaging

PendingCN121883556AImage enhancementImage analysisPerfusionDynamic speckle
The invention relates to the technical field of medical image processing and artificial intelligence analysis, in particular to a mechanical perfusion heart coronary artery recognition and flow velocity estimation method based on laser speckle imaging, and is suitable for donor heart function evaluation and organ quality screening before heart transplantation. Comprising the following steps: continuously imaging the surface of an isolated heart in a mechanical perfusion state to acquire a dynamic speckle image sequence, inputting the dynamic speckle image sequence into a wavelet enhancement nnU-Net model to generate a coronary artery segmentation mask, and applying the coronary artery segmentation mask to the dynamic speckle image sequence to extract image data only containing a coronary artery region, and then generating a blood flow index map, analyzing the periodic change of the blood flow index in the coronary artery region to construct a blood flow velocity change curve, and estimating the hemodynamic parameters of the coronary artery. According to the application, automatic coronary artery identification and quantitative estimation of the blood flow velocity can be carried out on the mechanically perfused isolated heart, so that rapid and accurate non-invasive evaluation on the coronary artery system of the donor heart before heart transplantation is realized.
Owner:HENAN ACADEMY OF MEDICAL SCIENCES

A method for evaluating organ state based on laser speckle and an organ perfusion system

PendingCN122171493AImage analysisScattering properties measurementsMicrocirculatory perfusionOptical flow
This invention relates to the field of bio-optical imaging technology, specifically to an organ status assessment method and organ perfusion system based on laser speckle imaging. The method utilizes high-frame-rate laser speckle imaging technology combined with a physiological signal gating algorithm. It extracts the original speckle image only during the diastolic window when organ motion is minimal. The original speckle image is then preliminarily corrected using a vibration-speculiar distortion model. Subpixel-level registration is then performed on the preliminarily corrected speckle image using optical flow, generating a high signal-to-noise ratio microcirculation perfusion distribution map free of motion artifacts. Based on the microcirculation perfusion distribution map, perfusion heterogeneity indices for each target assessment region are calculated to determine whether local blood flow abnormalities exist in the transported organ, thus achieving status assessment and real-time monitoring of the transported organ. This assessment method is applicable not only to organ transport but also to organ quality evaluation and immediate post-transplant assessment scenarios.
Owner:HENAN ACADEMY OF MEDICAL SCIENCES

Light sheet imaging apparatus and method

A laser speckle imaging apparatus 100 and method are provided herein. In an embodiment, the apparatus 100 for generating flow information of a biological sample 116 comprises an illumination optical device 115 operable to generate one or more illumination light sheets for selectively illuminating the biological sample 116 to produce corresponding scattered light; a first image acquisition device 135 operable to acquire the corresponding scattered light of each illuminated layer at a same wavelength as the illumination light sheet; and an image processing device 141 operable to construct 3-dimensional flow information of the biological sample 116 from speckle patterns of the acquired scattered light. An apparatus and method for imaging a biological sample using a specific scanning mirror and grating element is also discussed.
Owner:NATIONAL UNIVERSITY OF SINGAPORE

Coagulation point identification method based on laser speckles

The invention relates to the technical field of medical detection, in particular to a blood coagulation spot identification method based on laser speckles, which comprises the following steps: S1, performing beam expansion on optical fiber laser to generate a circular light spot covering a dialysis pot as a speckle excitation source; s2, sequentially arranging an optical filter and a polaroid in a speckle reflection path to filter ambient light and reflection speckles, and collecting a blood flow speckle image matrix; s3, using the speckle image matrix as an input to calculate a sliding window gray scale contrast and generate a blood coagulation degree map matrix; s4, setting a threshold value according to the blood coagulation degree diagram, judging an initial blood coagulation point, and calculating a blood coagulation area; and S5, correcting the threshold value and enhancing the edge in combination with the gray gradient and the blood flow velocity model, and outputting an optimized blood coagulation distribution and area correction result. According to the method, through high signal-to-noise ratio laser speckle imaging, based on preliminary recognition of the blood coagulation degree diagram, edge contrast enhancement and blood flow model correction, accurate recognition of the blood coagulation points and high-precision estimation of the blood coagulation area are achieved.
Owner:THE NAVAL MEDICAL UNIV OF PLA

Intelligent fire initial fire identification method and system based on AI vision

This invention discloses a smart fire prevention and control method and system based on AI vision, belonging to the field of fire prevention and control technology. This invention achieves accurate fire identification and response through a four-element acquisition architecture, cross-scale preprocessing, three-in-one AI inference, and dynamic closed-loop decision-making. The method includes: acquiring multimodal data using visible light, mid-wave infrared, laser speckle imaging, and gas sensing; outputting a four-dimensional purification feature set after laser speckle denoising, image registration, and spatiotemporal alignment; constructing a cross-modal fusion network, a dynamic threshold inferencer, and an edge incremental learning module to adaptively allocate feature weights and generate scene-adaptive thresholds to complete the initial fire assessment; and achieving risk classification and personalized early warning through a three-level decision-making mechanism. This invention can effectively identify open flames, trace smoke, and concealed fire sources, improving the comprehensiveness of perception, the accuracy of identification, and the adaptability of the scene, enabling early detection, early warning, and early response to fires.
Owner:ZHEJIANG ZHONGYAO FIRE PROTECTION CO LTD

Integrated confocal laser speckle microscopy imaging device

ActiveCN224436677UBeam splitterFirst light
This invention relates to the field of optical imaging technology and provides an integrated confocal laser speckle microscopy imaging device. The scanning box includes a polarizer, a beam expander, a half-wave plate, an achromatic cylindrical lens, and a polarizing beam splitter arranged sequentially according to the light propagation path. An achromatic double lens is disposed on one side of the first light-emitting surface of the polarizing beam splitter, and a galvanometer system and an achromatic double lens are disposed on one side of the second light-emitting surface of the polarizing beam splitter. The scanning box is provided with a first interface, a second interface, and a third interface. A light source, externally connected to the first interface, is located at the light inlet of the polarizer. A camera, externally connected to the second interface, receives the light emitted from the first light-emitting surface. A microscope, externally connected to the third interface, receives the light emitted from the second light-emitting surface. This embodiment realizes an integrated, modular laser speckle imaging system that maintains the high performance of confocal imaging while improving the system's stability and portability.
Owner:SHENZHEN INSTITUTE OF INFORMATION TECHNOLOGY

An entropy-guided real-time laser speckle imaging method, device and system

This application provides an entropy-guided real-time laser speckle imaging method, apparatus, and system, relating to the field of image processing technology. The method involves calculating the contrast of a laser speckle image of a target biological sample to obtain a first contrast image; downsampling the first contrast image at n downsampling rates to obtain n second contrast images; extracting the local entropy of each region in both the first and second contrast images; identifying regions containing blood vessels in both the first and second contrast images based on the extracted local entropy; and performing noise reduction on both the first and second contrast images to obtain multiple denoised images. These denoised images are then fused to obtain a third contrast image. By applying this application, real-time laser speckle imaging can be achieved with low sampling frame rates while maintaining image quality comparable to that with high sampling frame rates.
Owner:XIAN INST OF OPTICS & PRECISION MECHANICS CHINESE ACAD OF SCI