Frequency domain laser speckle imaging based blood flow velocity measuring method

A blood flow velocity and laser speckle technology, applied in the directions of diagnostic recording/measurement, medical science, sensors, etc., can solve problems such as not being effectively solved, errors, etc., to improve measurement stability, eliminate static noise, and improve measurement accuracy. degree of effect

Active Publication Date: 2014-12-03
亿慈(上海)智能科技有限公司
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Problems solved by technology

Although the effectiveness of the speckle contrast value has been greatly improved through the above methods, since the speckle image is still affected by various imaging environme

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  • Frequency domain laser speckle imaging based blood flow velocity measuring method
  • Frequency domain laser speckle imaging based blood flow velocity measuring method
  • Frequency domain laser speckle imaging based blood flow velocity measuring method

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Embodiment Construction

[0031] The present invention is described in detail below in conjunction with accompanying drawing:

[0032] Such as figure 1 As shown, the present invention provides a blood flow velocity measurement method based on frequency-domain laser speckle imaging, comprising the following steps:

[0033] S1: irradiate the laser beam on the object to be measured;

[0034] S2: Using the imaging system to image the object under test;

[0035] S3: using the image sensor to collect the original speckle image of the measured object;

[0036] S4: Calculate a single pixel in the original speckle image to obtain an autocovariance function of a single pixel, and normalize the autocovariance function of a single pixel, including the following steps:

[0037] S41: Use the formula (I) to perform Fourier transform on the dynamic speckle intensity of a single pixel point (x, y) in the time domain in the collected original speckle image, and convert it to the frequency domain:

[0038] ...

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Abstract

The invention discloses a frequency domain laser speckle imaging based blood flow velocity measuring method. The frequency domain laser speckle imaging based blood flow velocity measuring method comprises the following steps of illuminating laser beams on a measured object, imaging the measured object through an imaging system, collecting an original speckle image of the measured object through an image sensor, transferring dynamic speckle intensity with single pixel points being in a time domain of the collected original speckle image into a frequency domain, calculating the power spectral density, performing polynomial fitting on the power spectral density to obtain a smooth curve, transferring the smooth curve into the time domain through Fourier transform, calculating an autocovariance function of the pixel points and performing normalization, establishing a blood velocity measuring model, obtaining a relationship between the covariance function and the blood velocity and finally performing fitting to obtain a blood velocity value. The frequency domain laser speckle imaging based blood flow velocity measuring method has the advantages of not only eliminating static noise, improving the blood velocity measuring accuracy, avoiding influences from imaging environmental factors such as intensity and illumination angles and improving the measuring stability.

Description

technical field [0001] The invention relates to the field of biological tissue blood flow imaging, in particular to a blood flow velocity measurement method based on frequency-domain laser speckle imaging. Background technique [0002] Laser speckle contrast imaging is a technology that uses an optical imaging system to transmit laser speckle images to image blood flow in the whole field. The laser speckle contrast imaging system is mainly composed of a coherent light source and an image acquisition device. The coherent light is randomly superimposed after being scattered by biological tissue, and the random speckle pattern is collected by the image acquisition device for spatial contrast analysis, and finally the blood flow velocity is estimated. The laser speckle contrast imaging method has the characteristics of simple operation and strong practicability, so it has been widely used in the fields of biomedical research, clinical diagnosis, surgical guidance, skin, dentistr...

Claims

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Application Information

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IPC IPC(8): A61B5/0265
Inventor 童善保李皓刘祺卢洪阳李瑶
Owner 亿慈(上海)智能科技有限公司
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