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43 results about "Dynamic speckle" patented technology

In physics, dynamic speckle is a result of the temporal evolution of a speckle pattern where variations in the scattering elements responsible for the formation of the interference pattern in the static situation produce the changes that are seen in the speckle pattern, where its grains change their intensity (grey level) as well as their shape along time. One easy to observe example is milk: place some milk in a teaspoon and observe the surface in direct sunlight. You will see a "dancing" pattern of coloured points. Where the milk dries on the spoon at the edge, the speckle is seen to be static. This is direct evidence of the thermal motion of atoms, which cause the Brownian motion of the colloidal particles in the milk, which in turn results in the dynamic speckle visible to the naked eye.

Method and apparatus realizing quasi confocal fluorescent microscopic with dynamic speckle illumination

The present invention relates to a novel method and a novel device, incorporating dynamic speckle lighting with a conventional wide field fluorescence microscope organically to implement approximately confocal fluorescence microscopy (i.e., quasi-confocal fluorescence microscopy). The present invention employs an argon ion laser as the light source; the exciting light passes through a scattering object, a relay light path system for expanding and shaping, and then is coupled to the fluorescence microscope and focused to the sample. The stepping and revolution of the scattering object is controlled with a computer to produce a dynamic speckle pattern on the sample. The received fluorescent images are processed to obtain high-resolution spatial chromatographic images under no need to scan condition. The method can be used to obtain high-resolution three-dimensional chromatographic and microscopic image information of biological tissue samples in a non-intrusive manner. The device has simple structure, high cost-performance ratio, and is favorable for post data processing, easy to operate and apply; therefore, the device and method have a wide market application prospect and great significance for clinical diagnosis and life science research.
Owner:SHENZHEN UNIV

Frequency domain laser speckle imaging based blood flow velocity measuring method

The invention discloses a frequency domain laser speckle imaging based blood flow velocity measuring method. The frequency domain laser speckle imaging based blood flow velocity measuring method comprises the following steps of illuminating laser beams on a measured object, imaging the measured object through an imaging system, collecting an original speckle image of the measured object through an image sensor, transferring dynamic speckle intensity with single pixel points being in a time domain of the collected original speckle image into a frequency domain, calculating the power spectral density, performing polynomial fitting on the power spectral density to obtain a smooth curve, transferring the smooth curve into the time domain through Fourier transform, calculating an autocovariance function of the pixel points and performing normalization, establishing a blood velocity measuring model, obtaining a relationship between the covariance function and the blood velocity and finally performing fitting to obtain a blood velocity value. The frequency domain laser speckle imaging based blood flow velocity measuring method has the advantages of not only eliminating static noise, improving the blood velocity measuring accuracy, avoiding influences from imaging environmental factors such as intensity and illumination angles and improving the measuring stability.
Owner:亿慈(上海)智能科技有限公司

Complete and high-resolution test method for motion characteristics of particles in turbid media

The invention discloses a complete and high-resolution test method for the motion characteristics of particles in turbid media. The method comprises the following steps of: performing continuous, complete and real-time detection on the motion characteristics of the particles in the process of 'solution-colloid-sediment' of the turbid media by combining the resolution relation between the characteristic value of a speckle pattern and particle motion and utilizing a dynamic speckle test light path according to the particle light scattering theory; simultaneously, performing transient study on different critical points of the particle motion in the process by using a femtosecond laser test light path to perform the analysis of high spatial and temporal resolution on transient dynamics of the particles in the turbid media; and combining the two steps to realize the complete test with high spatial and temporal resolution characteristic on motion images of the particles in the process of 'solution-colloid-sediment' of the turbid media finally. The method is a non-contact, high-accuracy and real-time online detection method, has the characteristics that the operation is simple and the application range is wide, and can be widely used in the fields of medical science, pharmacy, chemical production and the like.
Owner:HENAN UNIV OF SCI & TECH

Microscopic imaging method and system based on double-core optical fiber light control and dynamic speckle illumination

The invention provides a microscopic imaging method and system based on double-core optical fiber light control and dynamic speckle illumination. The method is characterized in that a light control part of the device is formed by oppositely installing two two-core optical fibers of which the output end surfaces are processed into specific angles. Laser beams are respectively coupled into a two-core optical fiber through a single-mode optical fiber, a focusing light field is formed near an output end face, and cells to be detected are stably captured. And the cells rotate around a specific axis by adjusting the output power of each fiber core of the other two-core optical fiber. And after the cells rotate to a certain angle and reach a stable state every time, a tomographic image of the cells is acquired by using a dynamic speckle illumination wide-field fluorescence microscopy technology, and finally a three-dimensional structure image of the cells is reconstructed. The system constructed by the invention can be used for obtaining a three-dimensional structure image with high temporal and spatial resolution of a living single cell, has the characteristics of simple structure, low cost, simplicity and convenience in operation and the like, and has wide application prospects in numerous research fields such as biology, medicine, life science and the like.
Owner:GUILIN UNIV OF ELECTRONIC TECH

High-brightness controllable pseudo-thermal light source based on liquid crystal light valve modulation

The invention discloses a high-brightness controllable pseudo-thermal light source based on liquid crystal light valve modulation, which comprises a pulsed laser, an adjustable beam expanding and collimating system, a polarizer, a first analyzer, an adjustable aperture diaphragm, a liquid crystal light valve, a second analyzer and a liquid crystal light valve control system. The pulsed laser, the adjustable beam expanding and collimating system, the polarizer, the first analyzer and the adjustable aperture diaphragm are arranged on the same optical axis. The optical axis is arranged on the incident light optical axis of the liquid crystal light valve. The second analyzer is arranged on the reflected light optical axis of the liquid crystal light valve corresponding to the incident light optical axis. Laser light output by the laser finally irradiates the liquid crystal light valve controlled by a liquid crystal light valve control system. Through controlling the liquid crystal light valve, a dynamic speckle field, i.e. a pseudo-thermal light field is obtained. The thermal fluctuation of the high-brightness controllable pseudo-thermal light source produced by the invention can be truly recorded by the photoelectric detection system of a limited transmission band, the cross spectrum purity conditions satisfying a true-thermal light field can be obtained through controlling RGB images loaded on the liquid crystal light valve and the pseudo-thermal light field produced at any time is controllable.
Owner:SHANGHAI INST OF TECHNICAL PHYSICS - CHINESE ACAD OF SCI

High-brightness controllable pseudo-thermal light source based on liquid crystal light valve modulation

The invention discloses a high-brightness controllable pseudo-thermal light source based on liquid crystal light valve modulation, which comprises a pulsed laser, an adjustable beam expanding and collimating system, a polarizer, a first analyzer, an adjustable aperture diaphragm, a liquid crystal light valve, a second analyzer and a liquid crystal light valve control system. The pulsed laser, theadjustable beam expanding and collimating system, the polarizer, the first analyzer and the adjustable aperture diaphragm are arranged on the same optical axis. The optical axis is arranged on the incident light optical axis of the liquid crystal light valve. The second analyzer is arranged on the reflected light optical axis of the liquid crystal light valve corresponding to the incident light optical axis. Laser light output by the laser finally irradiates the liquid crystal light valve controlled by a liquid crystal light valve control system. Through controlling the liquid crystal light valve, a dynamic speckle field, i.e. a pseudo-thermal light field is obtained. The thermal fluctuation of the high-brightness controllable pseudo-thermal light source produced by the invention can be truly recorded by the photoelectric detection system of a limited transmission band, the cross spectrum purity conditions satisfying a true-thermal light field can be obtained through controlling RGB images loaded on the liquid crystal light valve and the pseudo-thermal light field produced at any time is controllable.
Owner:SHANGHAI INST OF TECHNICAL PHYSICS - CHINESE ACAD OF SCI

Dynamic speckle fluorescence microscopic imaging method and system based on four-core optical fiber light control

The invention provides a dynamic speckle fluorescence microscopic imaging method and system based on four-core optical fiber light control. The device is characterized in that a light control part of the device is formed by mounting a four-core optical fiber of which the output end face is processed into a specific angle. A laser beam is divided into four beams through a beam splitter, the four beams are coupled into a four-core optical fiber through single-mode optical fibers respectively, a Bessel light field can be formed near the output end face, cells to be detected are stably captured, the output power of fiber cores of the optical fibers can be changed by adjusting a modulator, and the cells are made to rotate around a specific axis. And after the cells rotate to a certain angle and reach a stable state every time, a tomographic image of the cells is acquired by using a dynamic speckle illumination wide-field fluorescence microscopy technology, and a three-dimensional structure image of the cells is finally reconstructed. The constructed system has the advantages of being simple in structure, low in cost, easy to operate and the like, and has wide application prospects in many research fields such as biology, medicine and life science.
Owner:GUILIN UNIV OF ELECTRONIC TECH

Double-sided dynamic shear testing device and method based on Hopkinson pressure bar system

The invention relates to the technical field of measuring devices, in particular to a double-sided dynamic shear testing device and method based on a Hopkinson pressure bar system, and the double-sided dynamic shear testing device comprises a rock sample, a testing device, a force application mechanism, a signal shear mechanism and a displacement shear mechanism, the force applying mechanism impacts a rock sample subjected to normal stress, and the displacement shearing mechanism collects dynamic change of the rock sample to obtain a dynamic speckle image and analyzes the dynamic speckle image to obtain a rock sample surface displacement field evolution law and a dynamic slip rate; an incident pulse signal, a reflection pulse signal and a transmission pulse signal which are generated when the force applying mechanism impacts the rock sample are acquired and analyzed through the signal shearing mechanism, so that incident energy, reflection energy and transmission energy are obtained; the problem that direct shearing of an existing dynamic shearing and friction measuring device based on the Hopkinson pressure bar cannot dynamically shear a rock structural surface under the action of medium-high strain rate dynamic load is solved.
Owner:CHONGQING UNIVERSITY OF SCIENCE AND TECHNOLOGY

Wide-field multispectral fluorescence microscopic imaging method and system based on dynamic speckle illumination

The invention provides a wide-field multispectral fluorescence microscopic imaging method and system based on dynamic speckle illumination. The system is characterized in that a mode-locked titanium sapphire femtosecond pulse laser is used as a light source. A femtosecond laser pulse with a wide spectral range forms a speckle pattern after passing through a scatterer, full-field illumination is formed in the field of view of the microscope objective, and different types of fluorophores in a biological sample to be detected are excited at the same time. Illumination speckle patterns are sequentially changed, a CCD camera detects and receives fluorescence images obtained through illumination of the dynamically-changed speckle patterns, and the wide-field multispectral fluorescence microscopic imaging method based on dynamic speckle illumination is achieved through a tomography extraction algorithm. The system constructed by the invention can simultaneously and quickly acquire three-dimensional space distribution images of different types of fluorophores in a biological sample, has the characteristics of high temporal and spatial resolution, simple structure, easiness in operation and the like, and has wide application prospects in the research fields of biology, medicine, life science and the like.
Owner:GUILIN UNIV OF ELECTRONIC TECH
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