Device and method for measuring particulate motion of turbid media by using dynamic speckle method

A dynamic speckle and particle technology, applied to the analysis of materials, instruments, etc., can solve the problems of limited application range, inability to detect, and failure to consider the non-uniformity of Gaussian laser beam light intensity, so as to achieve accurate measurement and eliminate the effect of influence

Inactive Publication Date: 2011-09-07
HENAN UNIV OF SCI & TECH +1
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Problems solved by technology

[0004] After literature search, the U.S. patent "Two-dimensional imaging of translucent objects in turbid media" (authorization number US5644429A, authorization date 1997.07.01) provides a 4F Fourier optical imaging system to realize the imaging of translucent objects in turbid media solutions. The imaging method of translucent objects, which can realize the imaging of translucent objects, has the disadvantage that it cannot detect the movement process of a large number of particles in turbid solutions; the US patent "Method and device for characterization of particles in clear and turbid media" (authorization number is US7528384B2, the date of authorization is 2009.05.05), which can realize the detection of the size, shape and concentration of fluorescent particles, but the measurement accuracy is low, and real-time measurement cannot be realized, which limits its appli

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  • Device and method for measuring particulate motion of turbid media by using dynamic speckle method
  • Device and method for measuring particulate motion of turbid media by using dynamic speckle method

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Embodiment Construction

[0020] The present invention will be further described below in conjunction with embodiment.

[0021] As can be seen from the accompanying drawings, the device for measuring the movement of particles in turbid media by the dynamic speckle method of the present invention includes a continuous wave laser 110, and a laser beam shaper 120, a beam reducer 130, Diaphragm 140, polarizer 151, sample cell 160; after the laser beam is scattered by the turbid medium particles in the sample cell 160, a converging mirror 171, a detector and Polarizer 152, CCD camera 181; In the backscattering light field, the direction deviating from the main optical axis at a specific angle is successively provided with a converging lens 172, an analyzer 153, and a CCD camera 182; in the forward scattering light field, the CCD The output of the camera 181 and the CCD camera 182 in the backscattered light field is connected to the input of the same computer 190; the CCD camera 181 is used to record the for...

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Abstract

The invention relates to a device and a method for measuring particulate motion of turbid media by using a dynamic speckle method. The device comprises a laser beam shaping contracting part, a forward scattering speckle field measuring part, a backward scattering speckle field measuring part, and a computer control and processing system. The method comprises the following steps: utilizing the device to record a forward scattering speckle field and a backward scattering speckle field generated by the particulate motion of turbid media and store the fields into the computer; according to the particle light scattering theory, choosing the forward scattering speckle field or backward scattering speckle field data; and analyzing the motion characteristic of the particulate, by utilizing a speckle chart characteristic value. The method is characterized by real time, dynamic and accuracy and can be widely applied to the fields such as medicaments, biology, life science, and the like.

Description

technical field [0001] The invention relates to a device and a method for measuring the movement of particles in a turbid medium, in particular to a device and a method for measuring the movement of particles in a turbid medium using a dynamic speckle method. Background technique [0002] Turbid medium refers to a medium with non-uniform refractive index that can produce both scattering and absorption and is mainly caused by scattering; most biological tissues (juice) contain a large number of scattering particles, which are typical turbid media. Therefore, the study of the motion characteristics of particles in turbid media has important academic value and scientific significance to the fields of medicine, biology, and life sciences, and is a frontier hotspot in modern scientific research. [0003] Speckle refers to the random intensity distribution of light and dark that is formed after coherent light is scattered by a rough surface or an inhomogeneous medium. When the irr...

Claims

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Application Information

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IPC IPC(8): G01N15/00
Inventor 李新忠聂兆刚台玉萍杜凯杨传径李立本
Owner HENAN UNIV OF SCI & TECH
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