Viscoelasticity Detection System and Method Based on Low Frame Rate Laser Speckle Contrast Imaging

A technology of laser speckle and detection method, which is applied in the direction of using light for diagnosis, diagnostic recording/measurement, medical science, etc. It can solve the problems of increasing system complexity and cost, and being unable to meet high spatial resolution tracking surface waves, etc., to achieve Benefits of Convenience, Complexity and Cost Reduction

A technology of laser speckle and detection method, which is applied in the direction of using light for diagnosis, diagnostic recording/measurement, medical science, etc. It can solve the problems of increasing system complexity and cost, and being unable to meet high spatial resolution tracking surface waves, etc., to achieve Benefits of Convenience, Complexity and Cost Reduction

CN108577806BActive Publication Date: 2021-01-19EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH +1

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  • Viscoelasticity Detection System and Method Based on Low Frame Rate Laser Speckle Contrast Imaging
  • Viscoelasticity Detection System and Method Based on Low Frame Rate Laser Speckle Contrast Imaging
  • Viscoelasticity Detection System and Method Based on Low Frame Rate Laser Speckle Contrast Imaging

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[0021] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0022] Such as figure 1 As shown, the embodiment of the present invention provides a viscoelasticity detection system 10 based on low frame rate laser speckle contrast imaging, which includes an excitation subsystem 11 and a laser speckle imaging subsystem 12 .

[0023] The excitation subsystem 11 is used to excite the surface of the tested sample 20 with a certain frequency of orthogonal oscillation, and form surface waves on the surface of the tested sample 20 .

[0024] Specifically, the excitation subsystem 11 includes a loudspeaker 111 and a loudspeaker driving device 112, the diaphragm of...

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Abstract

The invention discloses a viscoelasticity detecting system and method based on low frame rate laser speckle contrast imaging. The detecting method comprises the following steps that the surface of thedetected sample is subjected to orthogonal oscillatory excitation, and a surface wave is formed; a laser beam shining on the surface of the detected sample is emitted; a multi-frame laser speckle image is collected in a lower frame rate and exposure time; propagation velocity of an aliasing wave is obtained after calculating and processing; a propagation velocity of the surface wave is calculatedthrough the velocity relation between propagation velocity of an aliasing wave and the propagation velocity of the surface wave; and elasticity and viscidity of the detected sample are obtained. Thedetecting system comprises an excitation subsystem and a laser speckle imaging subsystem. Through detecting the surface wave under the orthogonal oscillatory excitation, and using the collected propagation velocity of the aliasing wave at the lower frame rate to calculate the propagation velocity of the surface wave, viscoelastic modulus of the detected sample is quantitatively solved, and complexity and the cost of the detecting is lowered; and reflection type laser speckle imaging is adopted and facilitating convenience of the actual detecting.

Description

technical field [0001] The invention relates to the technical field of viscoelasticity detection, in particular to a viscoelasticity detection system and method based on low frame rate laser speckle contrast imaging. Background technique [0002] The occurrence and development of diseases (such as atherosclerosis, skin tumors, etc.) will change the mechanical properties (such as elasticity and viscosity) of biological tissues. Biological tissue viscoelasticity measurement can be used to monitor the disease process and achieve the purpose of early diagnosis of disease. [0003] The viscoelasticity measurement of biological tissue reflects the mechanical properties of biological tissue by measuring the strain of biological tissue under the action of stress, in which the stress is applied to the measured sample through an external excitation device, and the strain-related parameters can be imaged by laser speckle contrast method to measure. Laser speckle contrast imaging dete...

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Application Information

Patent Timeline
19 Jan 2021
Publication
CN108577806B
IPC
A61B5/00; A61B5/02
CPC
A61B5/0059; A61B5/0082; A61B5/02007
Inventors
李鹏程; 陈肖