Viscoelasticity Detection System and Method Based on Low Frame Rate Laser Speckle Contrast Imaging

Abstract

The invention discloses a viscoelasticity detecting system and method based on low frame rate laser speckle contrast imaging. The detecting method comprises the following steps that the surface of thedetected sample is subjected to orthogonal oscillatory excitation, and a surface wave is formed; a laser beam shining on the surface of the detected sample is emitted; a multi-frame laser speckle image is collected in a lower frame rate and exposure time; propagation velocity of an aliasing wave is obtained after calculating and processing; a propagation velocity of the surface wave is calculatedthrough the velocity relation between propagation velocity of an aliasing wave and the propagation velocity of the surface wave; and elasticity and viscidity of the detected sample are obtained. Thedetecting system comprises an excitation subsystem and a laser speckle imaging subsystem. Through detecting the surface wave under the orthogonal oscillatory excitation, and using the collected propagation velocity of the aliasing wave at the lower frame rate to calculate the propagation velocity of the surface wave, viscoelastic modulus of the detected sample is quantitatively solved, and complexity and the cost of the detecting is lowered; and reflection type laser speckle imaging is adopted and facilitating convenience of the actual detecting.

Description

technical field [0001] The invention relates to the technical field of viscoelasticity detection, in particular to a viscoelasticity detection system and method based on low frame rate laser speckle contrast imaging. Background technique [0002] The occurrence and development of diseases (such as atherosclerosis, skin tumors, etc.) will change the mechanical properties (such as elasticity and viscosity) of biological tissues. Biological tissue viscoelasticity measurement can be used to monitor the disease process and achieve the purpose of early diagnosis of disease. [0003] The viscoelasticity measurement of biological tissue reflects the mechanical properties of biological tissue by measuring the strain of biological tissue under the action of stress, in which the stress is applied to the measured sample through an external excitation device, and the strain-related parameters can be imaged by laser speckle contrast method to measure. Laser speckle contrast imaging dete...

AI Technical Summary

Problems solved by technology

The sampling frame rate of laser speckle contrast imaging is related to the speed of the camera. The sampling frame rate of the camera is generally less than a few hundred frames per second, which cannot meet the high spatial resolution of surface wave tracking.

At this stage, the sampling frame rate of the system is generally increased through expensive high-speed cameras, or different parts of the signal are time-divided through precise synchronization between acquisition and excitation, but both high-speed cameras and synchronous methods will increase System complexity and cost

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