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Thrombi-resistant application of salvianolic acid B

A salvianolic acid and thrombus technology, applied in the antithrombotic application field of salvianolic acid B

Inactive Publication Date: 2009-09-16
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, aspirin's hemorrhagic side effects prompted the development of new antithrombotic treatments

Method used

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  • Thrombi-resistant application of salvianolic acid B
  • Thrombi-resistant application of salvianolic acid B
  • Thrombi-resistant application of salvianolic acid B

Examples

Experimental program
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Embodiment 1

[0061] Case 1

[0062] A 65-year-old female had a sudden cerebral thrombosis in the early morning. CT and MRI showed infarction in the brainstem area. She was treated with salvianolic acid B injection, a course of treatment every 5 days. After the first course of treatment was used up, her legs could move; After the first course of treatment is used up, he can walk with the help of his arm, and in the third course of treatment, he can walk with crutches.

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Abstract

The invention relates to the new application of the Chinese traditional medicine, in particular to the application of salvia extract, namely salvianolic acid B in the treatment and prevention of the thrombi. The test data indicate that the salvianolic acid B can prolong the starting time of the thrombi, restrain the mesentery thrombi caused by photochemistry.

Description

Technical field: [0001] The invention relates to a new application of traditional Chinese medicine products, in particular to the application of salvianolic acid B of salvia miltiorrhiza extract in the treatment and prevention of thrombus. Background technique: [0002] Salvia miltiorrhiza is a traditional Chinese medicine in China, and its main water-soluble components include methyl salvianolic acid, salvianolic acid, salvianol, β-sitosterol, β-sitosterol, 3,4-dihydroxybenzaldehyde, salvianolic acid A, salvianolic acid Phenolic acid B, catechin, rutin, protocatechualdehyde, protocatechuic acid, shikonic acid, lactic acid, vitamin E, etc. Salvianolic acid B is one of the main water-soluble components of Salvia miltiorrhiza. [0003] [0004] Salvianolic acid compounds have strong effects of inhibiting lipid peroxidation, scavenging superoxide anion and hydroxyl radical. Among them, salvianolic acid A and B had the strongest activity. Salvianolic acid B has obvious inhi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/343A61P7/02A61P9/10
Inventor 韩晶岩刘育英刘连欹孙凯王传社
Owner TIANJIN TASLY PHARMA CO LTD
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