Complex probiotic preparation for resisting salmonella pullorum infection and application of complex probiotic preparation

A technology of compounding probiotics and Salmonella, which is applied in the direction of antibacterial drugs, medical preparations containing active ingredients, and drug combinations, etc., can solve many problems such as improving resistance, improving the micro-ecological environment, and avoiding bacterial resistance. sexual effect

Pending Publication Date: 2019-07-12
HUAZHONG AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, at present, there are not many applications of compound probiotics for poultry, and most of the research is on pigs, which also requires us to continue to explore and study

Method used

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  • Complex probiotic preparation for resisting salmonella pullorum infection and application of complex probiotic preparation
  • Complex probiotic preparation for resisting salmonella pullorum infection and application of complex probiotic preparation
  • Complex probiotic preparation for resisting salmonella pullorum infection and application of complex probiotic preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A compound probiotic preparation against Salmonella pullorum infection, including Bacillus subtilis, Bacillus licheniformis, Bacillus coagulans, Bacillus amyloliquefaciens, Clostridium butyricum and Lactobacillus plantarum; the number of viable bacteria of Bacillus subtilis is 10 9 CFU / g, Bacillus licheniformis viable count is 10 9 CFU / g, the number of viable Bacillus coagulans is 10 8 CFU / g, the number of live bacteria of Bacillus amyloliquefaciens is 10 8 CFU / g, Clostridium butyricum viable count is 10 7 CFU / g, the number of viable Lactobacillus plantarum is 10 8 CFU / g.

[0025] The Bacillus amyloliquefaciens is Bacillus amyloliquefaciens H6, CCTCC NO: M2013249; the Lactobacillus plantarum is Lactobacillus plantarum ZN-3, CCTCC NO: M 2017286, and other strains are purchased from commercial channels.

[0026] The compound probiotic preparation prepared in Example 1 is used in the following examples.

Embodiment 2

[0028] A compound probiotic preparation for resisting Salmonella pullorum infection, its application process is as follows:

[0029] The 0-day-old broilers were randomly divided into 3 groups:

[0030] Control group (SPC): Salmonella infection without adding probiotics;

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Abstract

The invention relates to the technical field of probiotic preparations for resisting pathogenic bacterium infection in livestock breeding, and particularly discloses a complex probiotic preparation for resisting salmonella pullorum infection and application of the complex probiotic preparation. The complex probiotic preparation comprises bacillus subtilis, bacillus licheniformis, bacillus coagulans, bacillus amyloliquefaciens, clostridium butyricum and lactobacillus plantarum. The preparation specifically improves the body's resistance to salmonella pullorum infection, significantly improves intestinal mucosal immunity, reduces or avoids intestinal diseases, maintains intestinal microecological balance, reduces the addition of the long-term subtherapeutic dose and ultra-high dose of antibiotics for preventing and treating animal diseases in feed, and extremely has promoting significance.

Description

technical field [0001] The invention relates to the technical field of probiotic preparations for resisting pathogenic bacterial infection in livestock and poultry breeding, in particular to a compound probiotic preparation for resisting Salmonella pullorum infection and its application. Background technique [0002] Salmonella Pullorum (Salmonella Pullorum), also known as Salmonella in chickens, is the most serious pathogenic bacterium in the Salmonella genus to chickens. It can cause severe pullorum in young chickens and lead to a large number of deaths. Adult chickens are mostly invisible infections and can be infected or shed for a long time. , can spread horizontally and vertically, and bring serious economic losses to the poultry farming industry. Salmonella pullorum can colonize the intestinal tract and infect humans through eggs, meat and other products, posing a serious threat to food safety. The World Organization for Animal Health has listed pullorum as a B-type ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/747A61P31/04A61P37/04A61K35/742
CPCA61K35/742A61K35/747A61P31/04A61P37/04A61K2300/00
Inventor 金梅林杨丽康超雷振宇易海鸣
Owner HUAZHONG AGRI UNIV
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