Personalized 3D printed porous titanium-based tantalum-coated bone plate and its preparation method

Abstract

A personalized 3D-printed porous titanium-based tantalum metal-coated bone plate that has osteoinductive activity. The plate is prepared by using titanium metal powder or titanium alloy metal powder as a base material, and forming a tantalum coating on the surface of a porous titanium-based bone plate which is made by means of 3D-printing processing and which has a porous structure. The porous titanium-based tantalum metal-coated bone plate has a porosity of 50-80%, a flexural strength of 50-150 MPa, an elastic modulus of 2-30 GPa, a pore diameter of 200-800 μm and a tantalum coating thickness of 30-60 μm, and has sufficient strength while simultaneously having good osteoinductive performance. A bone plate implanted in a manner in which same conforms to the anatomical structure at a bone plate and a fracture part may have excellent bone integration with bone tissues, and the defect in which a conventional bone plate is easily loosened and fractures after being implanted in a body for a long time is avoided, so that permanent biological internal fixation is achieved.

Description

technical field [0001] The invention relates to a medical internal fixation device, in particular to a personalized 3D printed porous titanium-based tantalum-coated bone plate with osteoinductive activity and a preparation method thereof for medical fixation of long bone fractures of extremities. Background technique [0002] For fractures of the long bones of the extremities, open reduction and internal fixation are often used clinically. In traditional orthopedic surgery, the curvature of the bone plate and the screw implantation process are often used to ensure accuracy and avoid damage to important structures such as peripheral nerves, blood vessels, and organs. It needs to rely on the experience of the surgeon and the multiple times of fluoroscopy on the position of the bone plate and screw during the operation, resulting in a long operation time, the risk that the bone plate and bone cannot be tightly combined, and the screws will loosen and fail. At present, the commo...

AI Technical Summary

Problems solved by technology

[0008] The present invention aims at the above-mentioned traditional metal bone plate having many disadvantages in material properties, infection and aseptic loosening caused by the release of toxic metal ions, stress shielding, secondary removal, shape mismatch, etc., and researches and designs a 3D printing technology. Fabrication of porous titanium-based bone plate and tantalum coating, the bone plate can be personalized, permanent implantation, avoid stress shielding, have high histocompatibility and biomechanical properties, and can induce bone tissue generation

Images