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Medical hydrocolloid dressing and preparation method thereof

A hydrocolloid, medical technology, applied in the field of biomedical engineering, can solve the problems of ineffective hemostasis and pain relief, unproven safety, and poor wound healing ability, so as to promote the growth of wound granulation tissue, promote orderly growth, and promote healing Effect

Inactive Publication Date: 2019-08-09
湖北中部医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Medical hydrocolloid dressings currently on the market mainly use functional ingredients such as chitosan, sodium alginate, and silver ions. Olive oil or beeswax, which has good therapeutic effects on wounds such as anti-inflammatory, antibacterial, and hemostatic effects, is affected by the temperature of the preparation process. Restrictions, gel, plaster or emulsion materials are often used to add, which do not have adhesion and need to be used with other auxiliary materials, which is inconvenient to use
Patented and marketed medical hydrocolloid dressings mainly use functional ingredients such as chitosan, sodium alginate, and silver ions, which have poor wound healing ability, ineffective anti-inflammatory, hemostatic and pain-relieving effects, and their safety needs to be demonstrated, especially for various types of dressings. Chronic body surface wounds include ulcers, diabetic feet, venous / arterial ulcers of lower extremities, pressure sores, burns and scalds, etc. The wound treatment is slow and painful

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] This embodiment provides a medical hydrocolloid dressing, the main components of which include: by mass percentage, 52% of medical adhesive, 20% of sodium carboxymethylcellulose, 10% of bioactive glass, 1% of beeswax, and 8% of olive oil %, microcapsule wall material 9%.

[0038] The medical adhesive is medical polyisobutylene hot melt adhesive, and the microcapsule wall material is hyaluronic acid salt. Both the bioactive glass and the sodium carboxymethyl cellulose have a size of 150 mesh to 300 mesh. The medical polyisobutylene hot-melt adhesive, hyaluronic acid salt, bioactive glass and sodium carboxymethylcellulose are all commercially available.

[0039] The present embodiment also provides the preparation method of above-mentioned medical hydrocolloid dressing, and the steps are as follows:

[0040] Step 1, heating and melting the adhesive at 130°C;

[0041]Step 2, preparation of microcapsules: Soak the microcapsule wall material in water and heat to 70° C. an...

Embodiment 2

[0046] The present embodiment provides a medical hydrocolloid dressing, the main components include: by mass percentage, medical adhesive 51%, sodium carboxymethylcellulose 20%, bioactive glass 5%, beeswax 2%, olive oil 10% %, microcapsule wall material 12%.

[0047] The medical adhesive is medical polyisobutylene hot melt adhesive, and the microcapsule wall material is alginate. Both the bioactive glass and the sodium carboxymethyl cellulose have a size of 150 mesh to 300 mesh.

[0048] The present embodiment also provides the preparation method of above-mentioned medical hydrocolloid dressing, and the steps are as follows:

[0049] Step 1, heating and melting the adhesive at 140°C;

[0050] Step 2, preparation of microcapsules: Soak the microcapsule wall material in water and heat to 68° C. and stir for 30 minutes at a constant temperature to obtain a wall material solution. The mass ratio of the wall material in the wall material solution is 15%; beeswax, olive oil And s...

Embodiment 3

[0055] This embodiment provides a medical hydrocolloid dressing, the main components include: by mass percentage, medical adhesive 53%, sodium carboxymethylcellulose 25%, bioactive glass 10%, beeswax 1%, olive oil 5% %, microcapsule wall material 6%.

[0056] The medical adhesive is medical polyisobutylene hot melt adhesive, and the microcapsule wall material is hyaluronic acid salt. Both the bioactive glass and the sodium carboxymethyl cellulose have a size of 150 mesh to 300 mesh.

[0057] The present embodiment also provides the preparation method of above-mentioned medical hydrocolloid dressing, and the steps are as follows:

[0058] Step 1, heating and melting the adhesive at 145°C;

[0059] Step 2, preparation of microcapsules: Soak the microcapsule wall material in water and heat to 73° C. and stir for 30 minutes at a constant temperature to obtain a wall material solution. The mass ratio of the wall material in the wall material solution is 25%; beeswax, olive oil A...

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Abstract

The invention provides a medical hydrocolloid dressing and a preparation method thereof. The medical hydrocolloid dressing is prepared from, by total mass percentage, 30-60% of an adhesive, 20%-50% ofsodium carboxymethyl cellulose, 0.5%-20% of bioactive glass, 0.5%-10% of beeswax, 0.5-30% of olive oil, and 0.5-40% of microcapsule wall materials. The hydrocolloid dressing can be widely used, is suitable for protecting and treating various surface wounds including ulcers, diabetic feet, lower extremity venous / arterial ulcers, pressure sores, post-operative incisions, skin donor site wounds, burn wounds and the like, and has the effects of alleviating wound bleeding, relieving inflammation and pain, effectively absorbing exudates, maintaining a moist environment, promoting rapid wound regeneration and healing, and preventing and reducing scars.

Description

technical field [0001] The invention belongs to the technical field of biomedical engineering, and in particular relates to a medical hydrocolloid dressing and a preparation method thereof. Background technique [0002] Traditional medical dressings (cotton gauze, non-woven fabrics, etc.) are used on wounds. The materials are easy to obtain, easy to make, and low in price. However, the disadvantages are obvious. When there is a lot of wound exudate, it needs to be replaced frequently, and the dressing sticks to the wound surface. Pain, secondary trauma, and insufficient treatment of difficult-to-heal wounds such as ulcers. Traditional medical dressings for wound healing are mainly based on dry healing theory. Dry therapy faces many challenges that cannot be dealt with in the treatment of chronic wounds, such as the formation of dry, hard and thick scabs from necrotic tissue, pus and fluid accumulation under the scab, and putrefaction and stench , Sneaking and poor drainage ...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0004A61L26/0023A61L26/0057A61L26/0061A61L26/0066A61L26/008A61L2300/30A61L2300/402A61L2300/41A61L2300/412A61L2300/622A61L2400/04C08L1/286
Inventor 唐三
Owner 湖北中部医疗科技有限公司
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