Application of a flavonoid compound in snow chrysanthemum and its pharmaceutical composition in the preparation of medicines for treating acute pancreatitis

Abstract

The invention discloses the application of a flavonoid compound in snow chrysanthemum and its pharmaceutical composition in the preparation of medicine for treating acute pancreatitis. The invention provides an application of a flavonoid compound in the preparation of a medicine for treating acute pancreatitis. The flavonoids can significantly improve the necrosis of pancreatic acinar cells, and protect the local and systemic symptoms of two kinds of acute pancreatitis. The present invention will fill the medical value of snow chrysanthemum and the flavonoids isolated therein in the protection of pancreatitis, and provide new diagnosis and treatment methods and application prospects for clinical screening and / or preparation of drugs for the treatment of acute pancreatitis. a new choice.

Description

technical field

[0001] The invention relates to the application of a flavonoid compound in snow chrysanthemum and its pharmaceutical composition in the preparation of medicine for treating acute pancreatitis. Background technique

[0002] Acute pancreatitis (AP) is one of the common clinical acute abdomen, its etiology and pathogenesis are complex, the mortality rate remains high, reaching 30% to 60%, and various serious complications are prone to occur. Currently, acute pancreatitis is defined as an inflammatory disease characterized by acute inflammation and pancreatic parenchymal necrosis, and is divided into mild acute pancreatitis, moderately severe acute pancreatitis, and severe acute pancreatitis according to its severity. The pathogenic factors of acute pancreatitis are complex, including common biliary tract diseases, excessive alcohol intake, hyperlipidemia, drugs and surgical trauma. The pathogenesis of acute pancreatitis has not yet been elucidated. The early th...

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