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Insertable device for in-vivo sensing

A housing and guide wire technology, applied in applications, sensors, filters in blood vessels, etc., can solve problems such as inadvertently releasing clots and blocking animal blood vessels

Active Publication Date: 2019-08-23
SENSOME
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If a clot blocks the tip of the catheter, there is a risk that the clot may be inadvertently released during removal of the catheter, so that the clot could become an embolism through the bloodstream and block a vessel in another part of the animal

Method used

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  • Insertable device for in-vivo sensing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0279] Figure 25 A collection of amplitudes and phases of impedance spectra measured for cellular structures containing three cell types, platelets, smooth muscle cells and endothelial cells, respectively, is shown.

Embodiment 1

[0348] One example of a way in which the techniques described in this invention may be used is with an invasive smart guide wire. Invasive guidewires can be used to navigate through the vascular system. Using the sensors and analysis techniques described in the present invention, an invasive guidewire can characterize the tissue / substance it contacts and communicate the characteristics of that tissue / substance to the clinician. Invasive guidewires can also help add-on devices reach interventional sites in the patient.

[0349]In this embodiment, the guidewire includes a sensor (preferably an EIS sensor), an impedance spectrometer and a handle. The guidewire may also include additional components that may be inserted along its length during use. Sensors can be used to sense and characterize properties of tissues / substances with which they are in contact. For example, the sensor can be used to determine tissue / substance composition when used with impedance spectroscopy for hi...

Embodiment 2

[0352] Clinicians can use the guidewire described in Example 1 to determine the best treatment strategy for patients experiencing blocked arteries. Clinicians can use the guidewire to characterize the tissue / substance blocking the artery and then choose between different possible treatments based on that information. In some embodiments, the guidewire can provide treatment recommendations to the clinician based on the one or more characterizations it has made, and optionally based on data from previous treatments performed with the guidewire.

[0353] In this embodiment, a clinician can use the guidewire to assess and treat arterial lesions. The clinician can first point the guidewire at the site of the thrombus, optionally using the handle, and then penetrate the thrombus. Next, the clinician can use the guidewire to measure the blood clot and / or the composition of the tissue / substance that is blocking the artery. Clinicians can then determine the best treatment for blocked...

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PUM

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Abstract

Embodiments described relate to a medical device including an invasive probe that, when inserted into a duct (e.g. vasculature) of an animal (e.g., a human or non-human animal, including a human or non-human mammal), may be used to aid in diagnosing and / or treating a lesion of the duct (e.g. a growth or deposit within vasculature that fully or partially blocks the vasculature). The invasive probemay have one or more sensors to sense characteristics of the lesion, including by detecting one or more characteristics of tissues and / or biological materials of the lesion. A method for assembling the medical device is also described.

Description

[0001] Cross References to Related Applications [0002] This application claims priority under 35 U.S.C. §119(e) to U.S. Provisional Patent Application Serial No. 62 / 426881, filed November 28, 2016, entitled "INSERTABLE DEVICE FOR IN VIVO SENSING," the contents of which are incorporated in its entirety into the present invention. Background technique [0003] Blockage of blood vessels, including veins or arteries, can occur in various locations in animals (eg, humans or non-human animals) and can have significant consequences. For example, in an ischemic stroke, a blood clot completely or partially blocks blood flow in an artery in the brain. If the clot is not treated quickly, the lack of blood flow can cause irreparable damage to the brain. [0004] The blockage may be caused by a blood clot, which may be caused by the clotting of red and / or white blood cells and / or platelets within the blood vessel. Coagulation can be triggered by a variety of factors, including injury,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B5/053A61B17/22A61F2/95A61B18/14A61B5/02A61B5/296
CPCA61B5/6851A61B5/02007A61F2/01A61B5/0536A61B5/0537A61B5/0538A61B17/22A61F2/82A61F2/90A61B5/4836A61B18/1492A61B2562/046A61B2562/066A61F2002/016A61B2017/00026A61B18/1477A61B2017/22034A61B2017/22042A61B2017/2212
Inventor 布鲁诺·卡雷尔爱德华·I·武尔夫曼斯
Owner SENSOME
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