Rapid and steady image splicing method based on medical microscopic imaging

An image mosaic and microscopic imaging technology, which is applied in image enhancement, image analysis, image data processing, etc., can solve the problems of slow sample speed and low efficiency, and achieve the effect of reducing the amount of calculation and improving the efficiency of stitching

Active Publication Date: 2019-09-13
UNIV OF ELECTRONICS SCI & TECH OF CHINA
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Problems solved by technology

[0003] In order to overcome the problem of slow speed and low efficiency of manual observation of samples by doctors or researchers when it is necessary to observe microscopic images of multiple fields of view to make a diagnosis, the present invention proposes a solution for this, automatically combining high-resolution images from multiple fields of view. The pictures are automatically stitched and the mixed seam is eliminated to produce a seamless image, which achieves the purpose of fast and efficient, and the fast stitching also lays a solid foundation for improving the recognition rate of microscopic images

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  • Rapid and steady image splicing method based on medical microscopic imaging
  • Rapid and steady image splicing method based on medical microscopic imaging
  • Rapid and steady image splicing method based on medical microscopic imaging

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[0029] The present invention will be further described in detail below with reference to the accompanying drawings and examples, but the embodiments of the present invention are not limited thereto.

[0030] In biomedical and clinical research, it is highly desirable to view images of whole tissue sections at high resolution. However, it is difficult to obtain a single image with high resolution to view the entire sample. A common solution to this problem is to stitch several images with overlapping regions to form a composite image, where the main algorithm for extracting features is the scale-invariant feature transform (SIFT). SIFT is robust to rotation, scale, and lighting changes, but is time-consuming and computationally heavy.

[0031] The purpose of this invention is to develop a fast automatic splicing algorithm. In order to realize high-speed, high-precision microscopic image stitching, the present invention selects the ORB algorithm to extract image features, and ...

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Abstract

The invention discloses a rapid and steady image splicing method based on medical microscopic imaging, and belongs to the field of image processing. To achieve high speed, high-precision microscopic image splicing, the rapid and steady image splicing method selects an ORB algorithm to extract image features to prove that through processing, the same precision can be achieved through the method andalgorithms such as SIFT and SURF, and the calculated amount can be reduced on feature extraction. Besides, in order to eliminate the mixed gap to generate a seamless image, the rapid and steady imagesplicing method adopts a gradual-in gradual-out weighted average strategy, and in the final fusion stage, the rapid and steady image splicing method adopts the image indexing operation, so that multiple times of copying and moving of pixels are avoided to the maximum extent, and the time is further shortened. In addition, for the rapid and steady image splicing method, the whole algorithm processis accelerated by using a GPU, and the algorithm processing time is reduced to the minimum. Through calculation, for the rapid and steady image splicing method, accurate seamless splicing can be completed within about one second by using a 3 * 3 image with the resolution of 1360 * 1024.

Description

technical field [0001] The present invention is a fast and robust image mosaic technology based on medical microscopic imaging, specifically a method that can quickly and automatically realize the accurate and accurate stitching of a large number of high-resolution microscopic pictures such as 3×3, 5×5 or 10×10. A seamless approach. Background technique [0002] The patent application No. 201710879986.8 discloses an image acquisition and stitching method for a large-scale microscopic imaging area. The method matches the feature points, and the matching results are calculated by the RANSAC algorithm to calculate the affine transformation matrix of each matching point; after obtaining the transformation matrix, use the matrix to transform the two images into the same coordinate system; use the grayscale of the two images According to the matching points in the overlapping area, the overlapping area of ​​the two images is covered to complete the splicing." The method stitches ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T5/50G06K9/46
CPCG06T5/50G06T2207/20016G06V10/443G06V10/462
Inventor 张静霍一博李晔彬于腾秦驰王天鹤许浩杜晓辉王祥舟郝如茜倪光明刘娟秀刘霖刘永
Owner UNIV OF ELECTRONICS SCI & TECH OF CHINA
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