Application of a kind of basilica alkaloid analogue

A technology of alkaloids and analogs, applied in the field of medicine, can solve the problem of not finding anti-inflammatory active alkaloid monomer compounds and the like

Active Publication Date: 2021-05-14
SHANXI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still no anti-inflammatory active alkaloid monomer compounds

Method used

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  • Application of a kind of basilica alkaloid analogue
  • Application of a kind of basilica alkaloid analogue
  • Application of a kind of basilica alkaloid analogue

Examples

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Embodiment Construction

[0019] The technical solution of the present invention will be further clearly and completely described below in conjunction with the accompanying drawings and specific embodiments. Apparently, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0020] The structural formula of the basilica alkaloid analogue is

[0021]

[0022] The alkaloid analogues of the plant are used for inhibiting the production of nitric oxide induced by lipopolysaccharide LPS; The alkaloid analogs are used to prepare medicines for treating or preventing chronic inflammatory diseases. The inflammatory response induced by endogenous substances refers to the inflammatory response caused by inflammatory factors in the body, and the inflammator...

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Abstract

The invention belongs to the technical field of medicine, and discloses the application of a basil alkaloid analogue. The alkaloid analogues of the plant are used for inhibiting the production of nitric oxide induced by lipopolysaccharide LPS; The alkaloid analogs are used to prepare medicines for treating or preventing chronic inflammatory diseases. An anti-inflammatory drug, which is an alkaloid analogue with a structural formula of

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the application of an alkaloid analogue of baconium alkaloids. Background technique [0002] Inflammatory response is a repair mechanism for the body to maintain homeostasis in response to injury and infection. However, the occurrence of inflammation is accompanied by the generation of side effects, especially the development of persistent inflammation into chronic inflammation. Chronic inflammation is associated with the development of autoimmune diseases, cancer, neurodegenerative diseases, cardiovascular diseases, metabolic diseases and other diseases. The Chinese began using herbs to control inflammation as early as 4,000 years ago. Natural products and their derivatives have become the main source of anti-inflammatory drugs. [0003] Baibu alkaloids are a class of alkaloids with a unique structure isolated from the traditional Chinese medicine Baibu. It is r...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/55A61P29/00
CPCA61K31/55A61P29/00
Inventor 武兴康马开庆张梦晨秦雪梅
Owner SHANXI UNIV
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