Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of yin-nourishing preparation prepared from rhizoma coptidis, radix hedysari, rhizoma curcumae longae, radix rehmanniae and radix scutellariae to preparation of medicine for treating hypertension and/or hyperlipoidemia

A technology for high blood pressure and high blood fat, which is applied in the application field of Wuhuang Yangyin preparation in the preparation of drugs for treating high blood pressure and/or high blood fat, so as to achieve the effect of good blood fat, lower blood fat, and multi-drug selection

Active Publication Date: 2017-05-31
GUIZHOU MAQIKA PHARMA
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are no relevant reports on the joint action of extracts of Miao medicine Coptis chinensis, Heqi, turmeric, rehmannia root, and scutellaria baicalensis on the prevention and treatment of hypertension and / or hyperlipidemia, and researchers are also working on more medicinal uses of Wuhuang Yangyin preparations Research

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of yin-nourishing preparation prepared from rhizoma coptidis, radix hedysari, rhizoma curcumae longae, radix rehmanniae and radix scutellariae to preparation of medicine for treating hypertension and/or hyperlipoidemia
  • Application of yin-nourishing preparation prepared from rhizoma coptidis, radix hedysari, rhizoma curcumae longae, radix rehmanniae and radix scutellariae to preparation of medicine for treating hypertension and/or hyperlipoidemia
  • Application of yin-nourishing preparation prepared from rhizoma coptidis, radix hedysari, rhizoma curcumae longae, radix rehmanniae and radix scutellariae to preparation of medicine for treating hypertension and/or hyperlipoidemia

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1 5

[0017] Experimental Example 1 Effect of Wuhuang Yangyin Preparation on Antihypertensive Efficacy in Rats with Essential Hypertension

[0018] 1 material

[0019] 1.1 Animals

[0020] Adult spontaneously hypertensive rats, male, weighing about 300 g, were provided by Guiyang Medical College.

[0021] 1.2 Experimental drugs

[0022] Irbesartan tablets, produced by Shenzhen Haibin Pharmaceutical Co., Ltd., approval number: Guoyao Zhunzi H20000510;

[0023] Juming Jiangya Pills, produced by Beijing Tongrentang Technology Development Co., Ltd. Pharmaceutical Factory, approval number: Z11020495;

[0024] Wuhuang Yangyin Granules, produced by Chongqing Dongtian Pharmaceutical Co., Ltd., approval number: Z20120014.

[0025] 2 Experimental methods

[0026] 2.1 Grouping and processing:

[0027] Take 50 rats and divide them into 5 groups. Each group will be gavaged / fed once a day for 4 consecutive weeks, specifically: control group (group A): normal saline 2ml / d; irbesartan tablet ...

experiment example 2 5

[0043] Experimental Example 2 Effect of Wuhuang Yangyin Preparation on Blood Lipid Level

[0044] 1 material

[0045] 1.1 Animals

[0046] SD rats, male, weighing about 300 g, were provided by Guiyang Medical College.

[0047] 1.2 Feed

[0048] Cholesterol and sodium cholate were purchased from Jinan Xinniushan Biotechnology Co., Ltd.

[0049] The mass ratio of high-fat feed: 15% lard, 20% sucrose, 2.7% cholesterol, 0.3% sodium cholate, and the balance is basic feed.

[0050] 1.3 Experimental drugs

[0051] Pravastatin sodium tablets, produced by Daiichi Sankyo Pharmaceutical (Shanghai) Co., Ltd., approval number: Guoyao Zhunzi H20060271;

[0052] Qizhi Capsules, produced by Heilongjiang Tiange Pharmaceutical Co., Ltd., approval number: Guoyao Zhunzi B20020452;

[0053] Jiangzhining Granules, produced by Baishan Changbaishan Pharmaceutical Co., Ltd., approval number: Z22023374;

[0054] Each 1 / 3 of Wuhuang Yangyin Granules, Capsules and Tablets was prepared in Examples ...

experiment example 3 5

[0067] Experimental Example 3 Clinical Curative Effect of Wuhuang Yangyin Preparation on Vertigo Patients

[0068] 1. Objects and groups: 20 patients with hypertension and vertigo scale numbers > 4; 15 patients with hypertension complicated with cerebral arterial insufficiency; 10 patients with hypertension complicated with vertebral-basilar artery insufficiency; 25 patients with hypertension complicated with hyperlipidemia; 20 cases of blood lipids; randomly divided into 5 groups, respectively: control group, administration 1-2 group, wherein, no more than 10 cases of the same disease in the control group and administration group;

[0069] 2. Administration and method: administration group 1 was given Zhenju Jiangya Tablets (specification: produced by Changzhou Shenma Pharmaceutical Co., Ltd., approval number: Z20055385), 3 times a day, 1 tablet each time, 0.25g per tablet; the administration group 2 was given Wuhuang Yangyin Granules, once a day, 1 bag each time, 6g per bag;...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a medical purpose of a yin-nourishing preparation prepared from rhizoma coptidis, radix hedysari, rhizoma curcumae longae, radix rehmanniae and radix scutellariae, and particularly relates to application of the yin-nourishing preparation prepared from the rhizoma coptidis, the radix hedysari, the rhizoma curcumae longae, the radix rehmanniae and the radix scutellariae to a medicine for treating hypertension and / or hyperlipoidemia, and also comprises application of the yin-nourishing preparation prepared from the rhizoma coptidis, the radix hedysari, the rhizoma curcumae longae, the radix rehmanniae and the radix scutellariae to a medicine for treating a headache symptom caused by the hypertension and / or the hyperlipoidemia and application of the yin-nourishing preparation prepared from the rhizoma coptidis, the radix hedysari, the rhizoma curcumae longae, the radix rehmanniae and the radix scutellariae to a medicine for treating a dizziness symptom caused by the hypertension and / or the hyperlipoidemia. The invention provides a second medical purpose of the yin-nourishing preparation prepared from the rhizoma coptidis, the radix hedysari, the rhizoma curcumae longae, the radix rehmanniae and the radix scutellariae; more medication options are provided for clinically treating the hypertension and / or the hyperlipoidemia.

Description

technical field [0001] The present invention relates to the medical application of Wuhuang Yangyin preparation, in particular to the application of Wuhuang Yangyin preparation in remarking medicines for treating hypertension and / or hyperlipidemia. Background technique [0002] The main ingredients of Wuhuang Yangyin preparation are Coptis chinensis, Heqi, Turmeric, Rehmannia glutinosa, and Scutellaria baicalensis, all of which are made from authentic medicinal materials in Southwest China. Miao medicine commonly used by Miao people. Coptidis Miao language is Wabge leenc naemx (transliteration is Wang Lian stem), Hongqi Miao language is Dout hxaok (transliteration is bean confusion), turmeric Miao language is Voh had (transliteration is Woha), Rehmannia Miao language is Hfeex dab (transliteration It is fat da), and Scutellaria baicalensis is Hgeil ghab (transliterated as Ega) in Miao language. Wuhuang Yangyin granules made from these five medicinal materials are recorded in ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P3/06A61P9/12A61P1/08A61P25/00
CPCA61K36/48A61K36/539A61K36/718A61K36/804A61K36/9066A61K2300/00
Inventor 张芝庭张涛涛
Owner GUIZHOU MAQIKA PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products