Preparation method of active extract gel product taking Hirudinaria Manillensis freeze-dried powder as raw material

Abstract

The invention discloses a preparation method of an active extract gel product taking Hirudinaria Manillensis freeze-dried powder as a raw material. The method includes cleaning all fresh living Hirudinaria Manillensis, homogenizing, and freeze-drying to obtain freeze-dried powder; adding appropriate amount of pure water into the freeze-dried powder, stirring for extraction, filtering, collecting a filtrate, adding appropriate amount of pure water into residues, stirring for extraction, filtering, collecting the filtrate, and mixing the filtrate; adding appropriate amount of anhydrous ethanol into the filtrate, centrifuging, and collecting a supernatant as an active extractive solution for later use; and preparing carbopol gel matrix, adding sodium hydroxide to adjust pH value, slowly adding the active extractive solution into the prepared gel matrix, and stirring to obtain 20-40 antithrombin active units / g gel. The freeze-dried powder extract of Hirudinaria manillensis has very high activity, so that the extract can be made into cosmetics with high activity to ensure good effect; in addition, the extract is configured into cosmetics with different active units; and the gel product is convenient to manufacture, use and carry, and can further be applied locally and on the whole face as required.

Description

Technical field [0001] The invention relates to a preparation method of an active extract gel product using the freeze-dried powder of Phyllostachys hirsuta as a raw material, in particular to the technical field of preparation of active extracts. Background technique [0002] Hirudin, an active extract of the freeze-dried powder of Philippine cow leeches, is the strongest known thrombin-specific inhibitor, which can effectively improve blood cohesion and promote blood circulation. This effect has been applied in the field of cosmetics, for removing freckles, removing marks, reducing red blood streaks, improving skin tone, and reducing fine lines. At present, the cosmetics that use Philippine cow leeches as raw materials include powders, essential oils, essences, aqueous solutions, creams, ointments, etc., but there is no gel-type cosmetics that use Philippine cow leeches freeze-dried powder as the active extract. According to different activities, this type of cosmetics is used...

AI Technical Summary

Problems solved by technology

[0003] Since the active extract of Hirudo phenanthae is a kind of small molecule polypeptide compound with good water solubility, traditional processing methods such as drying and hanging will lose most of the activity, and the method of low-temperature drying can retain the activity to the greatest extent. Extraction of raw materials can obtain highly active extracts to ensure the efficacy of cosmetics; essential oils and essences have poor solubility and low utilization; creams and ointments need to be heated during the production process, which will cause denaturation and loss of active ingredients; Very inconvenient to use powder and solution