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Brain volume atrophy prediction method based on brain function network

A technology of brain function network and prediction method, applied in the field of brain volume atrophy prediction

Active Publication Date: 2019-10-01
BEIHANG UNIV
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AI Technical Summary

Problems solved by technology

To sum up, the existing brain network research only recognizes the changes in the characteristics of functional brain networks under the influence of diseases, and cannot predict the degeneration of brain structures based on the characteristics of functional networks.

Method used

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  • Brain volume atrophy prediction method based on brain function network

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Embodiment Construction

[0027] In order to make the technical problems and technical solutions to be solved by the present invention clearer, the following will describe in detail with reference to the accompanying drawings and specific implementation examples.

[0028] like figure 1 As shown, a method for predicting brain volume atrophy based on the brain function network of the present invention, the specific steps in the implementation case are as follows:

[0029] Step 1, processing of functional image data, analysis of functional data and calculation of brain volume;

[0030] Perform rectification, registration, normalization, and smoothing on functional image data. Extract the activated pixels from the functional data to obtain the BOLD time series E of each node i (t). In this example, there are 264 nodes in total, and the BOLD time series has a total of 300 sampling points, where i=1,2,...,264, t=1,2,...,300. The brain structure image was segmented into gray matter, white matter and cereb...

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Abstract

The invention discloses a brain volume atrophy prediction method based on a brain function network. The brain volume atrophy prediction method comprises the following steps: 1, processing function image data, analyzing the function data and calculating a brain volume; 2, establishing a brain function network; 3, calculating the average path length and the aggregation coefficient of the brain network; and 4, establishing a prediction model of brain volume atrophy. Through the steps, the brain volume atrophy prediction method establishes the mapping relation between the topological characteristics of the brain function network and the brain atrophy information, and provides the brain volume atrophy prediction method based on the brain function network. The brain volume atrophy prediction method has early warning, systematicness and robustness, and the research result of the brain volume atrophy prediction method can provide powerful method support for future prediction of brain volume atrophy, and can achieve early prevention and treatment of brain atrophy.

Description

technical field [0001] The present invention provides a method for predicting brain volume atrophy based on brain functional network, which relates to a method for predicting brain volume atrophy caused by aging or dementia based on fMRI functional correlation network indicators, which is an interdisciplinary technology of complex network and brain science field. Background technique [0002] Brain science is known as the "ultimate frontier" for understanding nature and human beings. In the scientific community, the "Brain Project" has been considered a greater project than the Human Genome Project. Human beings have been tirelessly exploring on the way to reveal the mysteries of the brain. After the European Union took the lead in launching the "Human Brain Project", the United States and Japan have also successively launched related brain research programs. The China Brain Project can be summarized as "one body and two wings": the one body is centered on understanding th...

Claims

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Application Information

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IPC IPC(8): G06Q10/04G06Q10/06G16H50/70
CPCG06Q10/04G06Q10/06393G06Q10/067G16H50/70
Inventor 郭澍李大庆刘涛刘浩
Owner BEIHANG UNIV
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