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Chinese herbal compound composition capable of treating anovulatory infertility and application thereof

An infertility, composition technology, applied in the field of traditional Chinese medicine compound composition, to achieve high cycle ovulation rate, high cycle ovulation rate and clinical pregnancy rate, the effect of small impact

Active Publication Date: 2019-10-22
苏州市吴江区中医医院(苏州市吴江区第二人民医院)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, due to long-term anovulation and excessive endometrial hyperplasia without the antagonistic effect of cyclic progesterone, there is still a high risk of developing endometrial cancer or breast cancer.

Method used

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  • Chinese herbal compound composition capable of treating anovulatory infertility and application thereof
  • Chinese herbal compound composition capable of treating anovulatory infertility and application thereof
  • Chinese herbal compound composition capable of treating anovulatory infertility and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation method (tablet) of embodiment 1 Chinese medicine compound composition

[0025] 1. A Chinese medicine compound composition for treating ovulatory infertility, which is made of the following raw materials in parts by weight:

[0026]

[0027] 2. A method for preparing a compound Chinese medicine composition for treating ovulatory infertility, comprising the following steps:

[0028] (1) Take each raw medicinal material according to the parts by weight of the above 1 and put it in a multifunctional extraction tank, add 10 times the amount of the total medicinal materials and soak for 0.5 hour; then decoct and extract for 1.5 hour, filter, and take the filtrate for subsequent use;

[0029] (2) Take the medicinal residues and add 6 times the amount of water to the total medicinal materials again, decoct for 1.5 hours, filter, and take the filtrate for subsequent use;

[0030] (3) Merge the two filtrates, concentrate under reduced pressure, and dry in vacu...

Embodiment 2

[0032] The preparation method (capsule) of embodiment 2 Chinese medicine compound composition

[0033] 1. A Chinese medicine compound composition for treating ovulatory infertility, which is made of the following raw materials in parts by weight:

[0034]

[0035] 2. A method for preparing a compound Chinese medicine composition for treating ovulatory infertility, comprising the following steps:

[0036] (1) Take each raw medicinal material according to the parts by weight of the above 1 and put it in a multifunctional extraction tank, add 8 times the amount of total medicinal materials and soak for 1 hour; then decoct and extract for 1 hour, filter, and take the filtrate for subsequent use;

[0037] (2) Take the filter residue and add water of 8 times the amount of the total medicinal materials again, decoct for 1 hour, filter, and take the filtrate for subsequent use;

[0038] (3) Merge the two filtrates, concentrate under reduced pressure, and dry in vacuo to obtain the...

Embodiment 3

[0040] The preparation method (granule) of embodiment 3 Chinese medicine compound composition

[0041] 1. A Chinese medicine compound composition for treating ovulatory infertility, which is made of the following raw materials in parts by weight:

[0042]

[0043] 2. A method for preparing a compound Chinese medicine composition for treating ovulatory infertility, comprising the following steps:

[0044] (1) Take each raw medicinal material according to the parts by weight of the above 1 and put it in a multifunctional extraction tank, add 12 times the amount of the total medicinal materials and soak for 1.5 hours; then decoct and extract for 2 hours, filter, and take the filtrate for subsequent use;

[0045] (2) Take the filter residue of step (1) and add water of 8 times the amount of the total medicinal materials again, decoct for 1.5 hours, filter, and take the filtrate for subsequent use;

[0046] (3) Merge the two filtrates, concentrate under reduced pressure, and dry ...

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Abstract

The invention discloses a Chinese herbal compound composition capable of treating anovulatory infertility and application thereof. The Chinese herbal compound composition is prepared from 1-12 parts of radix rehmanniae preparata, 1-10 parts of roasted rhizoma atractylodis macrocephalae, 1-7.5 parts of poria cocos, 1-6 parts of fructus corni, 1-6 parts of radix salviae miltiorrhizae, 1-9 parts of fructus rubi, 1-6 parts of rhizoma dioscoreae, 1-9 parts of radix glehniae, 1-6 parts of semen cuscutae, 1-7.5 parts of fructus rosae laevigatae and 1-6 parts of semen ziziphi spinosae. The Chinese herbal compound composition achieves a good treatment effect when applied to the clinical treatment of anovulatory infertility under the guidance of traditional Chinese medicine theory. Clinical observation results show that the Chinese herbal compound composition mostly promotes the ovulation of single dominant follicles, has little influence on the endometrium and makes endometrium development synchronized with follicle development, so that a high periodic ovulation rate and clinical pregnancy rate are obtained, and a good treatment effect on anovulatory infertility is achieved. Besides, the Chinese herbal compound composition is very low in toxic or side effect and safe and reliable in clinical medication.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine composition, in particular to a compound traditional Chinese medicine composition for treating ovulation disorder infertility and its application. Background technique [0002] The follicle consists of a central egg cell surrounded by granulosa cells and theca cells. Occurrence of follicle is a long process, including many complex changes of oocyte and its surrounding follicle cells. It takes about one year for the development of primordial follicles to the formation of dominant follicles, followed by primordial follicles, preantral follicles (more than 9 months), antral follicles (grade 4 follicles, 60 days), and preovulatory follicles. (25 days, including recruitment, selection, dominant follicle formation) four stages. The follicle formation of the ovary is a highly coordinated physiological process, and the growth and development of follicles are controlled by many factors. It not ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P15/08
CPCA61K36/076A61K36/23A61K36/284A61K36/39A61K36/40A61K36/43A61K36/537A61K36/725A61K36/73A61K36/738A61K36/804A61K36/8945A61K2236/331A61K2236/39A61K2236/51A61P15/08A61K2300/00
Inventor 刘月红袁春芳
Owner 苏州市吴江区中医医院(苏州市吴江区第二人民医院)
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