Homologous multi-concentration cell exposure system
A multi-concentration, cell technology, applied in the field of homologous multi-concentration cell exposure systems, can solve problems such as large sample consumption, low experimental efficiency, and inability to guarantee the homology of the test substance, saving experimental samples and improving experimental accuracy. degree, and the effect of easy recycling
Active Publication Date: 2019-10-22
BEIJING HUIRONGHE TECH
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Problems solved by technology
[0003] At present, the existing cell exposure systems at home and abroad are all single-concentration cell exposure systems, and one experiment can only complete the cell exposure of one concentration of the test substance, which cannot guarantee the homology of the test substance, and the experimental efficiency is low. Big
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[0041] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, reference will be made below figure 1 The embodiment of the multi-link opening and closing mechanism of the present invention will be further described.
[0042] Such as figure 1 As shown, the homologous multi-concentration cell exposure system of the present invention includes a gas source, a test substance source, a cell exposure unit and an exhaust gas treatment device. Among them, the air source is used to provide clean air, which can be provided by a compression pump; the source of the test substance provides the test substance, and if harmful gas is required for the experiment, aerosol can be used, and the source of the test substance can use an aerosol generating device.
[0043] In the homologous multi-concentration cell exposure system of the present invention, both the source of the test substance and the gas source are connected to a buffer t...
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The invention discloses a homologous multi-concentration cell exposure system including a tested substance source, a gas source and a plurality of cell exposure units and also including a first diluter and a plurality of second diluters connected with the tested substance source; first capillary tubes communicating with the tested substance source are arranged in the second diluters, the second diluters also communicate with the gas source, each second diluter is provided with a plurality of second capillary tubes communicating with the gas source, and the numbers of the second capillary tubesare different. A tested substance enters the first diluter and the second diluters through the first capillary tubes, and clean air generated by the gas source enters the second diluters through thesecond capillary tubes to dilute the tested substance; since the numbers of the second capillary tubes are different, the dilution ratios of the second diluters are different, and the concentrations of the test substance entering the cell exposure units are different. The system can achieve multi-concentration contamination with the same cell exposure system, ensures the homology of the experimenttest substance with different concentrations, and ensures the consistency of the physical and chemical characteristics of the test substance with different concentrations.
Description
technical field [0001] The invention relates to the field of cell exposure, in particular to a homologous multi-concentration cell exposure system, which can be widely used in environmental and health impact research, indoor air pollution evaluation research, respiratory-related diseases and drug screening research, etc. Background technique [0002] Hazardous gases refer to gases that are harmful to human health or work safety under normal or certain conditions; including toxic gases, flammable gases and asphyxiating gases. The harm of harmful gases to human beings is obvious to all. Taking cigarette smoke as an example, the smoke contains a large amount of harmful substances. After these harmful substances are inhaled into the human body, they will poison the living cells of the human body, thereby inducing cell canceration. Therefore, the technical centers of each cigarette factory need to study the specific influence of cigarette smoke on cell growth in order to conduc...
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Login to View More IPC IPC(8): C12M1/36C12M1/34C12M1/12
CPCC12M41/34C12M41/40C12M47/18
Inventor 郑劲林杨富成
Owner BEIJING HUIRONGHE TECH