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System and method for electronic biological sample analysis

A biological sample and sample analysis technology, applied in the field of electronic biological sample analysis, can solve the problems of lack of sensitivity, specificity, and high cost

Active Publication Date: 2019-10-29
CARDEA BIO INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This is a highly sensitive technique, but also requires a great deal of expertise or very expensive automation to run properly, and can take hours per experiment
[0009] All of these currently available tests are expensive, highly operator dependent, and lack the sensitivity and specificity to accurately and reliably detect many diseases - especially in the early stages of the disease (e.g. Lyme disease)

Method used

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  • System and method for electronic biological sample analysis
  • System and method for electronic biological sample analysis
  • System and method for electronic biological sample analysis

Examples

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Embodiment Construction

[0042] Embodiments of the present disclosure relate to systems and methods for performing analysis of biological samples. In some examples, a system for biological sample analysis includes an outer housing, a biological sample delivery system, and an electronic biological sample sensor system. The biological sample delivery system can be configured to deliver a liquid biological sample positioned external to the biological sample analysis system to the biological sample sensor system via one or more tubes connected to the sample chamber, wherein at least one side of the sensor chamber is exposed to the electronic biological sample sensor system The sensor chip in. In several examples, the electronic biological sample sensor system includes a sensor chip and an electronic connector electrically connected to the sensor chip, wherein the electronic connector is configured to deliver a source-drain voltage and a source-gate bias to a transistor in the sensor chip, and Current fro...

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PUM

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Abstract

The invention discloses a system and method for electronic biological sample analysis. A biological sample analysis device includes a casing that encloses a biological sample delivery system hydraulically coupled to a sensor, wherein the sensor includes a plurality of Graphene transistors and each transistor covalently bonds with a biomarker causing the electrical properties of the transistor to measurably change when the biomarker is exposed to corresponding antibodies within an infected biological sample.

Description

[0001] This application is a divisional application, the filing date of the original application is April 16, 2015, the application number is 201580035141.X (PCT / US2015 / 026254), and the title of the invention is "system and method for electronic biological sample analysis". technical field [0002] The present disclosure relates to electronic biological sample analysis. Background technique [0003] Diagnostic techniques that involve the detection of viral or bacterial infections, or other diseases, within biological samples generally do not have the sensitivity to directly detect the presence of infectious agents such as bacteria, viruses, or diseased tissue (eg, cancer) before an immune response occurs. Thus, most diagnostic techniques detect such infections or diseases by detecting antibodies produced by the patient's immune system in response to a particular condition. For example, these antibody detection technologies are currently unable to detect many diseases (such a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00G01N27/414G01N33/543
CPCB01L3/502707B01L3/502715B01L2200/027B01L2300/0636B01L2300/0645G01N33/54373G01N27/4145G01N27/4146
Inventor B·戈德史密斯
Owner CARDEA BIO INC