Ultrasonic extraction atomization auxiliary carbon fiber ionization device and method of using same to realize ionization

An atomization device and ionization technology, applied in the field of mass spectrometry, can solve the problems of low ionization efficiency of polypeptide compounds, inability to perform rapid and direct in-situ analysis, poor accuracy of quantitative analysis, etc., achieving significant progress and practical value , Strong practicability and convenient sampling effect
CN110398532APending Publication Date: 2019-11-01SHANGHAI INST OF ORGANIC CHEM CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI INST OF ORGANIC CHEM CHINESE ACAD OF SCI
Publication Date
2019-11-01

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Abstract

The invention discloses an ultrasonic extraction atomization auxiliary carbon fiber ionization device and a method of using the same to realize ionization. The device includes a carbon fiber ion source and a mass spectrometry sample input channel. A sampling and ionization end of the carbon fiber ion source is located in front of a port of the mass spectrometry sample input channel. An ultrasonicextraction atomization device is arranged near the sampling and ionization end of the carbon fiber ion source. The method of using the ultrasonic extraction atomization auxiliary carbon fiber ionization device of the invention to realize ionization includes the operations of: placing a sample, which contains an extraction solvent, on the ultrasonic extraction atomization device, then sequentiallycarrying out extraction and atomization on the sample by the ultrasonic extraction atomization device, and then ionizing the atomized sample by the carbon fiber ion source. The ultrasonic extraction atomization auxiliary carbon fiber ionization device provided by the invention has good an ionization effect on peptide compounds, and can qualitatively and quantitatively analyze complex samples without the need for preprocessing the to-be-tested samples.
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Description

technical field

[0001] The invention relates to an ultrasonic extraction atomization-assisted carbon fiber ionization device and a method for realizing ionization using the device, belonging to the technical field of mass spectrometry. Background technique

[0002] Mass spectrometry (MS) is characterized by fast analysis speed, strong specificity and high sensitivity. It is a powerful tool for analyzing complex mixtures, providing information about molecules, weight and chemical structure of analytes. In recent years, with the continuous improvement and innovation of related technologies, mass spectrometry has become one of the fastest-growing analytical techniques, and it has also played a decisive role in promoting the rapid development of other disciplines, especially life sciences, and opened up many emerging or interdisciplinary fields. At present, mass spectrometry is more and more widely used in the fields of chemistry and chemical engineering, biology and life scien...

Claims

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