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Method, system and computer program product for ion radiotherapy

A radiation therapy and ion technology, applied in the field of ion radiation therapy, can solve problems such as inaccurate energy transfer modeling, achieve the effect of increased calculation time and simple implementation

Active Publication Date: 2019-11-26
RAYSEARCH LAB
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Using averages as the basis for ion therapy dose calculations will result in inaccurate modeling of energy transfer

Method used

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  • Method, system and computer program product for ion radiotherapy
  • Method, system and computer program product for ion radiotherapy
  • Method, system and computer program product for ion radiotherapy

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Embodiment Construction

[0032] Figure 1 shows on three levels A, B and C the internal structure of the lung well known to those skilled in the art. The area marked A represents the entire lung with bronchi Al. The area marked B is an enlargement corresponding to circle B in the area marked A, showing how the bronchi branch into bronchioles B1. The area labeled C is a further magnification corresponding to circle C in the area labeled B, showing the division of the bronchioles into tiny air spaces called alveoli C1. Alveoli C1 are surrounded by lung tissue C2. It can be seen that there are multiple alveoli C1 within the lung tissue C2, and these alveoli lead to the fractal structure in the lung tissue. The density of the lung tissue C2 itself is about 1, that is, close to water. The density in air cavity C1 is close to zero. The average density in the lungs is usually 0.2 to 0.25 g / cm 3 Between, this indicates that in total, about 75-80% of the lungs are filled with air.

[0033] figure 2 Typic...

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Abstract

A method of performing dose calculations for ion radiotherapy compensating for tissue in which the density within a voxel may be inhomogeneous by approximating a portion of the voxel as an air cavity.For each dose voxel, the voxel is inscribed in a three- dimensional grid comprising a number of cells and the propagation of ions through the voxel is calculated based on the cell pattern in the at least one cell overlapping the voxel. Preferably, the voxel is inscribed in the three-dimensional grid in such a way that it overlaps at least one cell fully. Each cell comprises a first portion representing a first density corresponding to a density of a tissue and a second portion representing a second density corresponding to the density of air, the first and second portions forming a cell pattern.

Description

technical field [0001] The present invention relates to a method for ionizing radiation therapy of lung tissue. Background technique [0002] Radiation therapy, which uses ions such as protons to deposit energy in the patient's body, has many advantages. [0003] In ion-based radiation therapy, each ion will emit most of its energy towards the end of its path, forming a so-called Bragg peak. A key issue in treatment planning is to ensure that the Bragg peaks of all beams are placed within the treatment volume so that all parts of the treatment volume receive the prescribed dose while minimizing dose to surrounding volumes. [0004] The position of the Bragg peak is influenced by the kinetic energy Tp of each ion. The value of Tp is chosen such that ions with the lowest energy will stop in the region of the nearest end of the treatment volume, while ions with the highest energy will stop in the region of the farthest end of the treatment volume. Thus, ion-based radiation t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/103A61N2005/1087A61N5/1031
Inventor 埃里克·特拉内乌斯
Owner RAYSEARCH LAB