Method for shielding bad smell of veterinary compound traditional Chinese medicine

A technology of traditional Chinese medicine and smell, which is applied in the field of masking the bad smell of veterinary compound Chinese medicine, which can solve problems such as bad taste, and achieve the effects of low production cost, good taste masking effect and easy storage

Pending Publication Date: 2019-12-17
大梆(沈阳)动物保健有限公司
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The present invention adopts the spray drying method and the vacuum drying method to dry all the clathrate and clathrate liquid to obtain the taste-masking powder of traditional Chinese medicine, which can not only cover the bad smell of traditional Chinese medicine, but also retain all the active ingredients of the compound traditional Chinese medicine, and the method does not see public reports

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for shielding bad smell of veterinary compound traditional Chinese medicine
  • Method for shielding bad smell of veterinary compound traditional Chinese medicine
  • Method for shielding bad smell of veterinary compound traditional Chinese medicine

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0033] Preparation of Shuanghuanglian extract:

[0034] Honeysuckle 1875g, Scutellaria baicalensis 1875g, Forsythia 3750g, the above three flavors, scutellaria baicalensis, add water and decoct three times, the first time for 2 hours, the second and third time each for 1 hour, combine the decoctions, filter, and concentrate the filtrate to a relative density of 1.03-1.08 ( 80°C), adjust the pH value to 1.0-2.0 with 2mol / L hydrochloric acid solution at 80°C, keep it warm for 1 hour, let it stand for 24 hours, filter, wash the precipitate with water until the pH value is 5.0, and then use 70% ethanol Wash until the pH value is 7.0, dry at low temperature, and set aside; soak honeysuckle and forsythia in water for 30 minutes, decoct twice, 1.5 hours each time, combine the decoctions, filter, and concentrate the filtrate to a relative density of 1.20-1.25 ( 80°C), cool to 40°C, add ethanol to make the alcohol content reach 75%, fully stir, let stand for 12 hours, take the supernat...

Embodiment 1

[0079] Inclusion compound prescription:

[0080] Ginkgo biloba extract: 1g

[0081] β-cyclodextrin: 8g

[0082]Inclusion compound preparation method: Weigh 80g of β-cyclodextrin, add distilled water to dissolve, take another 10g of ginkgo biloba extract, keep the temperature at 70°C, slowly add the drug aqueous solution to the β-cyclodextrin solution under stirring at 400r / min, and stir 3h, the ginkgo extract inclusion compound 1 was obtained. At the same time, take 5 g of β-cyclodextrin, add distilled water to dissolve it, and take another 10 g of ginkgo extract, and keep the rest of the preparation method unchanged to obtain ginkgo extract inclusion compound 2.

[0083] Drying method: Spray-dry the above-mentioned clathrate and clathrate solution separately, set and control the inlet temperature of the spray dryer to 150°C, the feed rate to 10mL / min, the atomization pressure to 18kPa, and the air flow rate to 60m 3 / min. Finally, ginkgo extract taste-masking preparations...

Embodiment 2

[0088] Inclusion compound prescription:

[0089] Shuanghuanglian extract: 1g

[0090] β-cyclodextrin: 6g

[0091] Preparation method of clathrate: Weigh 6g of β-cyclodextrin, add distilled water to dissolve it, take another 1g of Shuanghuanglian extract, keep the temperature at 60°C, and slowly add the drug aqueous solution to the β-cyclodextrin solution under stirring at 400r / min, Stir for 2 hours to obtain inclusion compound 1 of Shuanghuanglian extract. All the conditions were kept unchanged, and the stirring was changed at a room temperature of 25° C. to obtain the inclusion compound 2 of Shuanghuanglian extract.

[0092] Drying method: Spray-dry the above-mentioned clathrate and clathrate solution, set the inlet temperature of the spray dryer to 140°C, the feed rate to 8mL / min, the atomization pressure to 16kPa, and the air flow rate to 50m 3 / min. Finally, taste-masking preparations 1 and 2 of Shuanghuanglian extract were obtained, the encapsulation efficiency was 91...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a method for shielding bad smell of a veterinary compound traditional Chinese medicine, and belongs to the field of traditional Chinese medicine preparations. The method comprises the following steps: preparing a saturated aqueous solution from a traditional Chinese medicine extract, adding the saturated aqueous solution into 2-10 times of a masking agent, stirring for 1-4hours under a water bath condition of 30-80 DEG C until a traditional Chinese medicine taste masking solution is formed, and drying the traditional Chinese medicine taste masking solution to obtain traditional Chinese medicine taste masking powder. The prepared traditional Chinese medicine taste masking powder can also be further made into a compound traditional Chinese medicine preparation, pet food, a pet health product or a feed additive for animals. According to the invention, the traditional Chinese medicines and cyclodextrin are made into an inclusion compound, and then the inclusion compound is made into the taste masking powder. Compared with the traditional Chinese medicine extract and cyclodextrin inclusion compound aqueous solution, the peculiar smell of the traditional Chinesemedicines is reduced, and the stability and compliance of the medicine are improved.

Description

technical field [0001] The invention discloses a method for masking the bad smell of veterinary compound traditional Chinese medicine, which belongs to the field of traditional Chinese medicine preparations. Background technique [0002] The chemical composition of Chinese medicinal materials is complex, and there are few known ingredients, and most of them contain a large amount of protein, fat, and alkaloids. These ingredients will produce unpleasant odors after oxidation and decomposition. Although these Chinese medicinal materials have been processed in the process of processing and preparation, their bad smell still cannot be eliminated. For animals, their senses of smell and taste are more sensitive, so animals are more sensitive to the bad taste of traditional Chinese medicine. These strong bad smells are unacceptable to animals, and some will produce nausea and vomiting when taking them, which seriously affects the use of Chinese medicines or veterinary medicinal pr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/69A23K10/30A23K20/163A23K40/30
CPCA61K47/6951A23K10/30A23K20/163A23K40/30
Inventor 姜斌乔彦恺夏超康东铭杜少范其他发明人请求不公开姓名
Owner 大梆(沈阳)动物保健有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap